Helping Women Meet Their Activity Goals: Randomised Trial Of A Personalised Program Delivered By Mobile Telephone
Funder
National Health and Medical Research Council
Funding Amount
$493,346.00
Summary
Cardiovascular disease is the leading cause of death in Australian women, but is less likely among women who are active. Because women are less active than men, and women with young children are the least active of all, we developed a program to increase postnatal women's physical activity. Women in the pilot study reported high program satisfaction and more physical activity, because the program focused on them (not their kids) and helped them prioritise time for physical activity.
The Burden Of Cancer - Prevention, Treatments, Costs, And Related Diseases
Funder
National Health and Medical Research Council
Funding Amount
$311,860.00
Summary
This research aims to increase knowledge on the development, optimal treatment, and costs of cancer and the associated risk factors, by applying advanced disease burden measures to comprehensive data gathered from several established and novel databases. This knowledge is important in advancing our understanding of those most vulnerable to cancer and in developing appropriate preventive strategies and health care for those at highest risk.
Efficacy Of Melatonin For Sleep Disturbance Following Traumatic Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$225,119.00
Summary
This randomized controlled trial will evaluate the effectiveness of melatonin, a naturally occurring hormone, in alleviating sleep disturbances in people with traumatic brain injury. If successful, melatonin therapy could substantially improve the quality of life of individuals with TBI, improving their participation in vocational, leisure and social activities and enhancing their emotional well-being.
Social Well-being And Engaged Living (SWEL) Intervention For Australian Youth At Risk Of Mental Health And Other Adverse Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$1,305,236.00
Summary
Adolescence is a period of rapid physical, emotional and social growth. Many young people lack the socio-emotional skills to negotiate the transition thorough adolescence, and are at risk of disengaging from education, family and community. This is the first clinical trial to investigate the efficacy of a telephone delivered intervention for increasing social engagement, emotional health and well-being of disengaged rural and urban youth.
Fluid resuscitation is widely used in the management of critically ill patients. There are a variety of different fluids available to doctors but there is little evidence regarding how effective they are. One of the most commonly used fluids, a hydroxyethyl starch was recently approved by the TGA for use in Australia. This project aims to compare how effective and safe this fluid is compared to another widely used fluid, saline, for resuscitation of critically ill patients in intensive care.
Caring For The Carer: Improving Self-efficacy To Provide Care And Reducing Anxiety Among Family Carers Of Primary Brain Tumour Patients
Funder
National Health and Medical Research Council
Funding Amount
$318,669.00
Summary
This fellowship will aim to improve self-efficacy and reduce anxiety among carers of primary brain tumour patients, who experience a significant burden due to their caregiving roles. This will be achieved through: (1) development of an online psychoeducational intervention; (2) pilot testing of the intervention; and (3) a randomised controlled trial of the intervention to determine its efficacy.
Motivational Interviewing With Cognitive-behavioural Therapy For Anxiety And Depression Following Traumatic Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$458,298.00
Summary
A large number of people with traumatic brain injury (TBI) experience mental health issues such as anxiety and depression. This randomized controlled trial examines the effectiveness of a cognitive behavioural therapy treatment program adapted for individuals with TBI. At the end of the study, recommendations can be made to rehabilitation practitioners and the wider community about management of mental health issues post TBI, to prevent prolonged distress and facilitate recovery.
Radiotherapy Treatment For Prostate Cancer - A Change In Practice Based On Direct Evidence For Targeting And Toxicity Effects Using Real Outcomes Data
Funder
National Health and Medical Research Council
Funding Amount
$555,129.00
Summary
Radiotherapy for prostate cancer treatment will be more effective when we have better knowledge of what patient anatomy needs to be targeted, and what needs to be avoided. This project will combine data collected during a large Australasian prostate cancer radiotherapy trial, ‘RADAR’, with data collected using new patient imaging methods to determine how patient anatomy impacts on the effectiveness of their treatment and the side-effects they experience.
Developing New Treatment Approaches For Severe And Treatment Resistant Depression
Funder
National Health and Medical Research Council
Funding Amount
$2,060,520.00
Summary
Depression is a common, disabling problem. One third of depressed patients do not respond to treatment with standard medications and psychological therapy. This research program will focus on developing new treatment approaches for these people: optimising electroconvulsive therapy, a highly effective treatment, developing new non invasive brain stimulation treatments, generating new knowledge on how best to use ketamine treatment.
Electrical Stimulation With A “Random Noise” Pattern: A New Approach For The Treatment Of Depression
Funder
National Health and Medical Research Council
Funding Amount
$523,160.00
Summary
This study is a world first, examining the use of a novel technology to treat depression by stimulating the brain mildly and non invasively. The study will examine the effectiveness of a 4-week course of Transcranial “Random Noise” Stimulation to treat depression, and will also measure whether improvement in mood is accompanied by a restoration of brain plasticity or adaptability.