Applying Active Hospital-based Case Ascertainment To Assess Vaccine Effectiveness And Safety
Funder
National Health and Medical Research Council
Funding Amount
$258,741.00
Summary
Australia makes a considerable investment in vaccination, and the public are entitled to expect that vaccines are both safe and effective. The growing complexity of the vaccine schedule requires the development of new and flexible systems to monitor vaccine performance. This project aims to do this using surveillance nurses embedded in children's hospitals to actively find cases of diseases which are potentially vaccine-preventable as well as those which might have occurred as a side effect of v ....Australia makes a considerable investment in vaccination, and the public are entitled to expect that vaccines are both safe and effective. The growing complexity of the vaccine schedule requires the development of new and flexible systems to monitor vaccine performance. This project aims to do this using surveillance nurses embedded in children's hospitals to actively find cases of diseases which are potentially vaccine-preventable as well as those which might have occurred as a side effect of vaccination.Read moreRead less
Severe Influenza: Epidemiology, Clinical Aspects & Public Health Responses
Funder
National Health and Medical Research Council
Funding Amount
$120,659.00
Summary
The 2009 flu pandemic exposed gaps in Australia's surveillance & public health policies. Using a hospital surveillance system (FluCAN) set up after the emergence of the pandemic virus, I will assess epidemiological, clinical & public health aspects of influenza to answer questions such as: what is the effectiveness of the influenza immunisation program? What is the burden of disease of severe influenza? Which forms of surveillance are best for different settings in Australia & in Asia-Pacific?
The Population Impact Of Human Papillomavirus Vaccination On Circulating Genotypes
Funder
National Health and Medical Research Council
Funding Amount
$249,259.00
Summary
Infection with human papillomavirus (HPV) is very common. Persistent infection can cause abnormal changes to cervical cells as found on Pap smears and if untreated, over time can develop into cervical cancer. Recently, a vaccine was introduced in Australia for women aged 12-26. To monitor the effectiveness of this vaccine, young women aged 18-22 will be asked to self-collect a sample for HPV detection which will determine if HPV types targeted by vaccine are reducing in prevalence.
Ongoing Prospective Audit Using High Quality Data And Database Linkage To Improve The Outcomes Of Macular Disease
Funder
National Health and Medical Research Council
Funding Amount
$843,237.00
Summary
FRB! is a national collaboration of retinal research centres that will collect data during the usual patient consultation. We will track the risks and benefits of the new treatments for macular disease which will inform the development of evidence based clinical management guidelines to assist the clinician to deliver the most appropriate treatment in the safest, most cost effective manner. We aim to support this with information from linked population health databases.