Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for l ....Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for liposomes. This provides a significant PhD training opportunity and brings an international focus to the development of planar patch-clamp electrophysiology in Australia. The project has significant commercial potential by developing both the planar patch-clamp electrophysiology techniques for liposomes and producing a novel biomimetic mechanosensitive biosensor.Read moreRead less
Novel Silicon-Based Photonic Devices. Silicon's pre-eminence in high-speed digital electronics does not extend to optoelectronics where the demand is for devices that can generate, guide, detect and process light. However, the properties of silicon are dramatically altered when it is reduced to nanometre dimensions. Advances in the understanding of such effects and in the fabrication and application of nanoscale silicon have provided the prospect of new and innovative Si-based photonic devices, ....Novel Silicon-Based Photonic Devices. Silicon's pre-eminence in high-speed digital electronics does not extend to optoelectronics where the demand is for devices that can generate, guide, detect and process light. However, the properties of silicon are dramatically altered when it is reduced to nanometre dimensions. Advances in the understanding of such effects and in the fabrication and application of nanoscale silicon have provided the prospect of new and innovative Si-based photonic devices, and of fully integrated electronic and photonic functionality. This project aims to extend the understanding of nanoscale silicon and to develop and prototype novel Si-based photonic devices based on this material.Read moreRead less
The Physical and Optical Properties of Self-Assembled Si Nanocrystals. The properties of nano-scale materials can differ significantly from those of their bulk counterparts. As such, they can provide materials with new and novel properties as well as proving a useful test of modern theories. An outstanding example of the significance of such effects is provided by quantum confined silicon structures, such as porous or nanocrystalline silicon, which exhibit luminescence efficiencies up to a milli ....The Physical and Optical Properties of Self-Assembled Si Nanocrystals. The properties of nano-scale materials can differ significantly from those of their bulk counterparts. As such, they can provide materials with new and novel properties as well as proving a useful test of modern theories. An outstanding example of the significance of such effects is provided by quantum confined silicon structures, such as porous or nanocrystalline silicon, which exhibit luminescence efficiencies up to a million times greater than bulk silicon. This project aims to understand the novel optical properties and interactions that underpin potential applications of this technologically important material.Read moreRead less
Devices that use Ion Channels. The proposed device would supply the community of researchers in Australia and internationally with new techniques to enable them to quickly and conveniently investigate properties of ion channels and to speed the screening of potential ion channel targets for pharmaceutical hits and leads. In addition, the tethered membrane technology will be developed to fill an unmet need for a quick and biologically relevant test of EMC hazards. This will enhance the science an ....Devices that use Ion Channels. The proposed device would supply the community of researchers in Australia and internationally with new techniques to enable them to quickly and conveniently investigate properties of ion channels and to speed the screening of potential ion channel targets for pharmaceutical hits and leads. In addition, the tethered membrane technology will be developed to fill an unmet need for a quick and biologically relevant test of EMC hazards. This will enhance the science and technology infrastructure within Australia, taking it into original and exciting directions, contribute to training young Australian scientists and students, as well as enhance Australia's competitive position in the field of nanobiotechnology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100067
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
The Vevo 2100 Micro-ultrasound plus LAZR Photoacoustic Imaging Platform . The Vevo 2100 micro-ultrasound plus LAZR photoacoustic imaging platform: The Vevo/LAZR ultrasound/photoacoustic imaging facility will allow researchers to achieve multiple outcomes: to visualise and quantify, non-invasively, tissue and molecular structures; the movement and behaviour of cells; and the delivery patterns of administered imaging dyes and nanoparticles in mouse models and reconstructed tissues. This will enabl ....The Vevo 2100 Micro-ultrasound plus LAZR Photoacoustic Imaging Platform . The Vevo 2100 micro-ultrasound plus LAZR photoacoustic imaging platform: The Vevo/LAZR ultrasound/photoacoustic imaging facility will allow researchers to achieve multiple outcomes: to visualise and quantify, non-invasively, tissue and molecular structures; the movement and behaviour of cells; and the delivery patterns of administered imaging dyes and nanoparticles in mouse models and reconstructed tissues. This will enable researchers to obtain anatomical, functional, physiological and molecular data simultaneously and in real-time, with resolution down to 40 micrometres. This will translate into both user efficiency and laboratory cost effectiveness, but more significantly is expected to result in greater understanding of fundamental mechanisms regulating the body's cell and tissue functions.Read moreRead less
Formation of nanocrystals (or nanocrystals with core/shell structure) and applications for photonics, floating gate and magnetic memory. Materials that contain nanometre-sized crystallites of a second material can exhibit novel optical, electrical and magnetic properties that have direct technological application. However, it is often difficult to control the size and concentration of the small crystals using conventional synthesis techniques. This project will overcome these limitations by ex ....Formation of nanocrystals (or nanocrystals with core/shell structure) and applications for photonics, floating gate and magnetic memory. Materials that contain nanometre-sized crystallites of a second material can exhibit novel optical, electrical and magnetic properties that have direct technological application. However, it is often difficult to control the size and concentration of the small crystals using conventional synthesis techniques. This project will overcome these limitations by exploiting the unique properties of pulsed-laser heating to produce the crystals. It will also investigate the optical, electrical and magnetic properties of these new materials and asses their suitability for super-dense data storage, solid-state lighting and advanced detection systems.Read moreRead less
Switching mechanisms in nonvolatile resistive memory using high-k dielectrics. Growth in the use of portable electronic devices, such as cameras, phones and MP3 players has resulted in an increased demand for low-power, high-density, non-volatile memory (NVM). One class of such memories aims to use resistance changes in thin dielectric films as a means of storing information. This project aims to develop a better understanding of these devices and to develop new and innovative processes for co ....Switching mechanisms in nonvolatile resistive memory using high-k dielectrics. Growth in the use of portable electronic devices, such as cameras, phones and MP3 players has resulted in an increased demand for low-power, high-density, non-volatile memory (NVM). One class of such memories aims to use resistance changes in thin dielectric films as a means of storing information. This project aims to develop a better understanding of these devices and to develop new and innovative processes for controlling data storage. The project is based on collaboration between researchers at the ANU and Silanna, an Australian start-up company aiming to develop and commercialise such technology.Read moreRead less
Novel Materials for Dye Sensitised Solar Cells. Solar energy is the most attractive renewable energy source. Dye sensitised solar cells (DSSCs) are one type of device that can harvest this energy, offering advantages of low materials cost and ease of fabrication when compared to alternative devices. This project aims to develop efficient, flexible DSSCs by using polymer substrates in place of glass. Novel surface modification approaches and microwave processing will be employed to fabricate the ....Novel Materials for Dye Sensitised Solar Cells. Solar energy is the most attractive renewable energy source. Dye sensitised solar cells (DSSCs) are one type of device that can harvest this energy, offering advantages of low materials cost and ease of fabrication when compared to alternative devices. This project aims to develop efficient, flexible DSSCs by using polymer substrates in place of glass. Novel surface modification approaches and microwave processing will be employed to fabricate the nanporous semiconductor electrodes on polymer substrates and to improve cell efficiency. Improved dyes and new electrolyte systems, such as plastic crystals, will be incorporated into the cell to improve efficiency, durability and stability.Read moreRead less
MICROWAVE PROCESSING OF FLEXIBLE DYE SENSITISED SOLAR CELLS. Solar energy is the most attractive renewable and environmentally sustainable energy source. Dye sensitised solar cells (DSSCs) are one type of device that can harvest this energy, offering advantages of low materials cost and ease of fabrication when compared to silicon-based solar cells. This project aims to develop efficient, flexible DSSCs by using polymer substrates in place of glass. Microwave processing will be employed to fabr ....MICROWAVE PROCESSING OF FLEXIBLE DYE SENSITISED SOLAR CELLS. Solar energy is the most attractive renewable and environmentally sustainable energy source. Dye sensitised solar cells (DSSCs) are one type of device that can harvest this energy, offering advantages of low materials cost and ease of fabrication when compared to silicon-based solar cells. This project aims to develop efficient, flexible DSSCs by using polymer substrates in place of glass. Microwave processing will be employed to fabricate the semiconductor layers on polymer substrates. Novel surface modification approaches will be examined to facilitate microwave processing and improve cell efficienRead moreRead less
Charge transport and trapping in high-k dielectric films containing self-assembled nanocrystals. Growth in the use of portable electronic devices such as mobile phones, iPods, MP3-players and personal digital assistants (PDA's) has resulted in increased demand for low-power, high-density Flash memory. However, existing memory devices are difficult to scale to smaller dimensions and lower power without severely compromising reliability. This project will investigate the synthesis and properties ....Charge transport and trapping in high-k dielectric films containing self-assembled nanocrystals. Growth in the use of portable electronic devices such as mobile phones, iPods, MP3-players and personal digital assistants (PDA's) has resulted in increased demand for low-power, high-density Flash memory. However, existing memory devices are difficult to scale to smaller dimensions and lower power without severely compromising reliability. This project will investigate the synthesis and properties of a new class of materials that have the potential to overcome these limitations. Read moreRead less