Discovery Early Career Researcher Award - Grant ID: DE140101056
Funder
Australian Research Council
Funding Amount
$380,156.00
Summary
Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-partic ....Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-particle level and the choice of optimal SERS-active three-dimensional superstructures for use will be guided by empirical structure-activity correlations in combination with computer simulations. Tumour biomarkers for breast cancer will be employed as the model target for establishing the detection platform in a portable configuration for point-of-care diagnostics.Read moreRead less
Surface tension-confined microfluidics: moving towards a flexible platform for diagnostics. The point-of-care industry is poised to fulfil the international need for effective and mobile diagnostics tools; however current strategies are restricting this from becoming a reality. Surface tension-confined microfluidics provide an opportunity to meet the requirements necessary for flexible platform for point-of-care devices.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100115
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploi ....High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploit interfacial phenomena and to tailor processing-microstructure-composition correlations, so as to design new materials with the best performance possible. Probes with unique capabilities will measure surface morphology, optical properties, elemental composition and crystallographic phase.The facility will be the first in Australia to offer a comprehensive study of structure and properties at high temperature.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100569
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Ultra-Porous Devices by Synergistic Aerosol and Atomic Layer Depositions. The project aspires to develop a scalable low-cost approach for the synthesis and integration of ultra-porous films in nanodevices. The project intends to deposit atomic layers onto aerogel-like nanoparticle networks, self-assembled by thermophoresis of flame-made aerosols. This would increase the atomically-deposited layer mass by several hundred-fold per cycle and result in ultra-porous films with electrochemically activ ....Ultra-Porous Devices by Synergistic Aerosol and Atomic Layer Depositions. The project aspires to develop a scalable low-cost approach for the synthesis and integration of ultra-porous films in nanodevices. The project intends to deposit atomic layers onto aerogel-like nanoparticle networks, self-assembled by thermophoresis of flame-made aerosols. This would increase the atomically-deposited layer mass by several hundred-fold per cycle and result in ultra-porous films with electrochemically active surface areas. It is intended that the project will demonstrate the fabrication of solid–gas, solid–liquid and solid–solid nanointerfaces, which will be applicable to key emerging technologies such as wearable medical diagnostics.Read moreRead less
Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Neuromorphic Sensing and Diagnostics with Carbon: Towards a Biomimetic Nose. Neuromorphic electronics emulates cognitive processes of the brain and like the brain, is capable of extracting features and recognising patterns within data with extremely low energy requirements. Carbon materials are naturally adapted to neuromorphic electronics and uniquely form a compatible interface for sensing molecules in liquid and gaseous media. This project aims to develop a carbon-based neuromorphic electroni ....Neuromorphic Sensing and Diagnostics with Carbon: Towards a Biomimetic Nose. Neuromorphic electronics emulates cognitive processes of the brain and like the brain, is capable of extracting features and recognising patterns within data with extremely low energy requirements. Carbon materials are naturally adapted to neuromorphic electronics and uniquely form a compatible interface for sensing molecules in liquid and gaseous media. This project aims to develop a carbon-based neuromorphic electronic sensing device and couple it with carbon based neuromorphic pattern recognition technology to build an ‘artificial nose’ for improved health and environmental monitoring. Intended outcomes will include a technology for low-cost and rapid diagnostic services.
Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100098
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise ....Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise—from across nine universities—in advanced structured optical fibres, complex fibre diagnostic systems, nanoscale imaging, and environment monitoring, to design and implement the next generation of technologies that will reduce the impact of climate change through reduced energy consumption and vastly improved health diagnostics.Read moreRead less
Core-scale geodynamic rock-typing of reservoir rock. This project aims to develop a robust classification method for reservoir rock incorporating static, dynamic and mechanical attributes via multiscale digital core analysis using the concept of regional measures. Rock-types are used to populate reservoir models in a sophisticated routine of geological classification, spatial modelling and uncertainty analysis. Introducing high-resolution rock-types incorporating hydraulic properties and compact ....Core-scale geodynamic rock-typing of reservoir rock. This project aims to develop a robust classification method for reservoir rock incorporating static, dynamic and mechanical attributes via multiscale digital core analysis using the concept of regional measures. Rock-types are used to populate reservoir models in a sophisticated routine of geological classification, spatial modelling and uncertainty analysis. Introducing high-resolution rock-types incorporating hydraulic properties and compaction allows the development of a new generation of reservoir simulators. The project aims to derive a consistent high-resolution definition of rock-types incorporating compaction for petrophysical, geological and reservoir engineering purposes. This would greatly enhance our capacity to develop thinly layered reservoirs with direct applications in 4-D seismic reservoir characterisation and the development of unconventional reservoirs.Read moreRead less
New-generation low-fouling coatings for membrane and metal surfaces for dairy processes. This project will create new coatings that provide high levels of resistance to membrane and metal surfaces fouling in the dairy industry. The project will enable the implementation of a family of readily applicable low-fouling membrane coatings that will significantly reduce operational costs.
Transistor-based sensor technology for fast, reliable and accurate in situ monitoring of recycled wastewater. Water recycling is becoming critical for water supplies worldwide, due to declining natural supplies of fresh water, combined with increasing demand. The greatest community and industry concerns over recycled water are quality assurance and relative cost. Ensuring quality requires monitoring of contaminants, yet no single real-time technology exists to measure the myriad of potential con ....Transistor-based sensor technology for fast, reliable and accurate in situ monitoring of recycled wastewater. Water recycling is becoming critical for water supplies worldwide, due to declining natural supplies of fresh water, combined with increasing demand. The greatest community and industry concerns over recycled water are quality assurance and relative cost. Ensuring quality requires monitoring of contaminants, yet no single real-time technology exists to measure the myriad of potential contaminants. This project will develop technology using AlGaN/GaN-based transistors, sensitised to different contaminants, enabling multi-analyte real-time sensor arrays. In situ monitoring systems based on such arrays will be fast, accurate, reliable, low-cost, and applicable to a broad variety of water recycling projects.Read moreRead less