Epidemiology Of Allergic Diseases And The Role Of Early Life Eczema
Funder
National Health and Medical Research Council
Funding Amount
$416,306.00
Summary
Eczema prevents our children from getting a healthy start to life, increases their risk of developing asthma and hay-fever, and we don’t know how to prevent this condition. Dr. Lowe will help identify causes and the outcomes of eczema and allergic diseases in early life, by using a number of important research projects. This research includes an intervention trial that aims to prevent the development of allergic disease and sensitisation, which Dr Lowe leads
School Versus Community-based Albendazole Deworming For Control Of Soil Transmitted Helminths In School-age Children In The Philippines – A Cluster Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,336,408.00
Summary
Intestinal parasites are a global health problem. The World Health Organization recommends regular distribution of deworming drugs, targeting school aged children. This is effective for the children receiving the drugs but does not have an impact in the wider community. We aim to determine the best strategy for delivery of deworming drugs, to achieve the maximum benefit both for children and wider community, by directly comparing the benefits of a school-targeted vs a community-mass approach.
Chronic Disease Epidemiology In Different Populations: Risk Factors, Detection And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$621,458.00
Summary
To investigate causes, detection and prevention of diabetes, cardiovascular disease, and kidney disease in Aboriginal and international populations, I will maintain a long-term cohort with a 20-year follow-up in Aboriginal people and to analyse several large repeated cross-sectional data collected over 25 years in China. For the next 5 years, I will continue to to provide critical epidemiological evidence for the development of health policies and clinical guidelines related to chronic diseases ....To investigate causes, detection and prevention of diabetes, cardiovascular disease, and kidney disease in Aboriginal and international populations, I will maintain a long-term cohort with a 20-year follow-up in Aboriginal people and to analyse several large repeated cross-sectional data collected over 25 years in China. For the next 5 years, I will continue to to provide critical epidemiological evidence for the development of health policies and clinical guidelines related to chronic diseases in different populations.Read moreRead less
Generational And Developmental Pathways Of Childhood And Adolescent Obesity: A Three Generation Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$1,281,100.00
Summary
There are no community-based follow-up (FU) studies of three generations able to examine the impact of earlier generational factors on the developmental pathways of obesity in third generation. The Mater-University of Queensland Study of Pregnancy (MUSP) cohort now has data covering the grandmothers' (GI) reproductive life course and a FU of their children (GII) into adulthood. We now propose a new study of the "children-of-the-children" who are the grandchildren (GIII) of GI and children of GII
Congenital Cytomegalovirus: Understanding The Long-term Outcomes And Identifying Opportunities For Secondary Prevention
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Cytomegalovirus is a herpesvirus that can be transmitted from mother to baby during pregnancy. Congenital cytomegalovirus (cCMV) can cause damage to the developing central nervous system leading to long-term disabilities including cerebral palsy and hearing loss. This epidemiological research program seeks to investigate cCMV risk factors and burden, opportunities for early detection of neuro-developmental disabilities and to study the effects of postnatal antiviral therapies in this population.
A Randomised Controlled Trial Of Daily Antibacterial Mouthwash To Reduce Pharyngeal Gonorrhoea Among Men Who Have Sex With Men (MSM)
Funder
National Health and Medical Research Council
Funding Amount
$376,730.00
Summary
Gonorrhoea is a common sexually transmitted infection (STI) among gay men, and the throat is the commonest site of infection. There is early data to suggest Listerine mouthwash can be used to prevent gonorrhoea. Our study will examine whether men use Listerine every day will reduce the risk of gonorrhoea in the throat compared those who use another mouthwash product which does not have an effect on gonorrhoea.
HIV Pre-exposure Prophylaxis In Men Who Have Sex With Men: Investigating Impacts On HIV Incidence And Novel Methods Of Engagement
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
HIV infections are increasing in gay men and other men who have sex with men (MSM) in Australia and Indonesia. A promising new HIV prevention strategy is HIV pre-exposure prophylaxis (PrEP), which involves HIV-negative individuals taking one pill containing HIV treatments per day to prevent infection. PrEP is highly effective when taken correctly. Access to PrEP is currently very limited. Studies to investigate the best ways to implement PrEP services are required in Australia and Indonesia.
Respiratory infections are common in children during the first two years of life, where they may experience six to eight infections each year. Complications are common, and between 3-5% of all infants are hospitalised. Available information on children has largely come from hospitalised patients. Information about illness in and cost to the community is scarce. To this aim, a cohort of children will be followed from birth to two. Information about infections and their cost will be recorded and a ....Respiratory infections are common in children during the first two years of life, where they may experience six to eight infections each year. Complications are common, and between 3-5% of all infants are hospitalised. Available information on children has largely come from hospitalised patients. Information about illness in and cost to the community is scarce. To this aim, a cohort of children will be followed from birth to two. Information about infections and their cost will be recorded and analysed.Read moreRead less
Reducing Unintended Pregnancies Among Female Sex Workers In Kenya Using MHealth: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$92,161.00
Summary
This research aims to reduce the high rates of unintended pregnancy experienced by female sex workers (FSW) in Kenya. It involves the development of a health promotion program delivered by mobile phone (mHealth intervention) to improve FSWs’ knowledge of SRH and reduce their risk of unintended pregnancy. The intervention will be trialled with 860 FSWs from 86 sex work venues in Mombasa. If effective, it can be implemented to improve women’s health in many and diverse settings.
New Technologies To Reduce The Population Burden Of Sexually Transmitted Infections
Funder
National Health and Medical Research Council
Funding Amount
$772,605.00
Summary
I propose a five year program of public health research on the evaluation of innovative technologies to prevent sexually transmitted infections (STIs) and their adverse consequences in populations at highest risk; Aboriginal and Torres Strait Islander people, youth, men who have sex with men and people in high STI-burden resource-limited countries. My research over the next five years will lead to substantial improvements in the health of people at greatest risk of STIs.