Early Detection And Intervention For Infants At High Risk Of Motor Impairments
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
My proposed research program involves several distinct yet related projects addressing i) early detection and ii) early intervention for infants at high risk of movement problems including cerebral palsy. This research will provide the highest quality evidence base that is needed to identify those children most at risk early in development and improve our understanding of which interventions are most effective, so that scare health care resources can be targeted appropriately.
Ontogeny Of Toll (TLR) Function In Normal And Allergic Children: The Impact Of Microbial-rich Environments
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Reduced exposure to bacteria during early life has become a leading candidate to explain the escalating rate of allergic disease. Despite this, the development and maturation of the pathways involved in normal recognition of bacteria in children has not been explored. In this proposal we set out to address this critical shortcoming in both normal and allergic children. Mapping normal maturation of such pathways will help us to identify better early markers of allergic disease.
Enabling Personalised Risk Assessment For Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Bowel cancer screening will be most effective in disease prevention if it is applied proportionately to individual person's risk. Risk-based screening requires a risk calculator to assess personal risk. By utilising existing large, international datasets, I will identify the risk factors specific for different bowel cancer types and incorporate them to upgrade the prediction model that I have developed. This will achieve more accurate risk prediction to enable personalised risk-based screening.
What Can Parents Do To Prevent Mental Health Problems In Their Teenage Children?
Funder
National Health and Medical Research Council
Funding Amount
$424,905.00
Summary
Research shows that there are things parents can do to prevent depression, anxiety and alcohol misuse problems in their teenage child, but many parents do not know what specific actions they can take. Through the work of this fellowship, I propose to increase our understanding of how specific parenting behaviours can influence young people's risk of developing depression and anxiety problems. I will also translate research evidence into specific parenting strategies parents can use to protect th ....Research shows that there are things parents can do to prevent depression, anxiety and alcohol misuse problems in their teenage child, but many parents do not know what specific actions they can take. Through the work of this fellowship, I propose to increase our understanding of how specific parenting behaviours can influence young people's risk of developing depression and anxiety problems. I will also translate research evidence into specific parenting strategies parents can use to protect their child from these problems.Read moreRead less
To reduce Australia's future dementia burden, it is imperative to develop methods to identify those Australians at the very early stage of dementia. To achieve this goal, we are establishing multidisciplinary research projects to track disease progression from the very early stage. These projects use cutting-edge neuroscience technologies to examine how the mind and brain change in dementia. My goal is to discover novel methods for early detection, and develop early intervention strategies.
Reducing The Injury And Disease Burden Attributable To Alcohol: Methodological, Aetiological And Intervention Studies.
Funder
National Health and Medical Research Council
Funding Amount
$408,412.00
Summary
The research examines the influence of individual, social and environmental factors on drinking behaviour, and seeks to determine the effectiveness of strategies to prevent alcohol-related harm, with a particular focus on youth drinking. A series of studies is proposed, examining the validity of methods for measuring drinking behaviour; social and environmental factors, and interventions. The findings will have relevance to reducing the burden of alcohol-related injury and disease in Australia.
People with psychotic illness, even with good treatment, do not tend to make functional recovery. They are over represented among the unemployed, the homeless, and have poorer physical health and earlier death than the general population. Despite the significant personal, societal and economic cost of these poor outcomes there has been little research into these areas. This fellowship builds on my work in vocational recovery to broaden knowledge about, and interventions for, functional recovery ....People with psychotic illness, even with good treatment, do not tend to make functional recovery. They are over represented among the unemployed, the homeless, and have poorer physical health and earlier death than the general population. Despite the significant personal, societal and economic cost of these poor outcomes there has been little research into these areas. This fellowship builds on my work in vocational recovery to broaden knowledge about, and interventions for, functional recovery in first episode psychosis.Read moreRead less
Epidemiology Of Allergic Diseases And The Role Of Early Life Eczema
Funder
National Health and Medical Research Council
Funding Amount
$416,306.00
Summary
Eczema prevents our children from getting a healthy start to life, increases their risk of developing asthma and hay-fever, and we don’t know how to prevent this condition. Dr. Lowe will help identify causes and the outcomes of eczema and allergic diseases in early life, by using a number of important research projects. This research includes an intervention trial that aims to prevent the development of allergic disease and sensitisation, which Dr Lowe leads
Randomised Controlled Trial Of Early Intervention To Improve Sexual And Couple Functioning After Prostate Cancer
Funder
National Health and Medical Research Council
Funding Amount
$405,000.00
Summary
Treatment for localised prostate cancer has a long term negative impact on the sexuality, quality of life, and relationship quality of Australian men and their intimate partners. This study will trial a remote access couples based sexuality intervention for this patient and carer group that has potential for broader translation into community and acute health care settings. This approach will also have broader application for chronic disease self management for other health conditions.