ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Epigenetic silencing in vertebrates: evolution and function from the bottom-up. The primary benefits are contribution to Australia's knowledge base and raising the profile of functional genomics in Australia, with the research priority of Frontier Technologies for Building and Transforming Australian Industries and priority goals in Breakthrough Science and Frontier Technologies. This project focuses on important biological questions surrounding gene regulation and sex chromosome evolution. Inte ....Epigenetic silencing in vertebrates: evolution and function from the bottom-up. The primary benefits are contribution to Australia's knowledge base and raising the profile of functional genomics in Australia, with the research priority of Frontier Technologies for Building and Transforming Australian Industries and priority goals in Breakthrough Science and Frontier Technologies. This project focuses on important biological questions surrounding gene regulation and sex chromosome evolution. International attention has already resulted in genome characterization of Australian icons (wallaby, Tasmanian devil and platypus), more research on these, and other Australian animals, will further highlight the importance of Australian fauna and impact positively on our scientific profile.Read moreRead less
Origin and Evolution of Mammalian Dosage Compensation. The primary benefits are contribution to Australia's knowledge base and raising the profile of functional comparative genomics in Australia, with the research priority of 'Frontier Technologies for Building and Transforming Australian Industries' and priority goals in 'Breakthrough Science and Frontier Technologies'. This project addresses fundamental questions about the evolution of mammalian X-chromosome inactivation, of importance as a mo ....Origin and Evolution of Mammalian Dosage Compensation. The primary benefits are contribution to Australia's knowledge base and raising the profile of functional comparative genomics in Australia, with the research priority of 'Frontier Technologies for Building and Transforming Australian Industries' and priority goals in 'Breakthrough Science and Frontier Technologies'. This project addresses fundamental questions about the evolution of mammalian X-chromosome inactivation, of importance as a model for epigenetic change, and sex chromosomes, which has engaged some of the greatest genetic minds over nearly a century. Therefore my results will attract wide international interest and impact positively on Australia's scientific profile, and further highlight the importance of Australian mammals.Read moreRead less
ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit ne ....ARC Centre in Bioinformatics. The Australian Centre for Genome-Phenome Bioinformatics will examine how the genome comes to life in the mammalian cell during differentiation and development. We will model, visualise and experimentally validate the complex cellular systems and regulatory networks that control the transformation of genomic information into biological structure and function. We will develop novel approaches and tools to improve health, optimise agricultural production and exploit new cell technologies. The Centre will build critical mass and national focus in bioinformatics to generate the human capital and intellectual property that Australia needs to compete in advanced bioscience and biotechnology.Read moreRead less
Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Aus ....Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Australia, and consolidate their roles as leading outlets for Indigenous content and coverage. These outcomes are also expected to improve public understanding of issues affecting Indigenous Australians and contribute to more informed and inclusive policy discussions.Read moreRead less
Mobile Indonesians: social differentiation and digital literacies in the twenty first century. This is the first dedicated study of the social implications of mobile telephony's recent and rapid popularisation throughout the country. This project will study metropolitan, urban and rural users to understand how mobile phones create the new and unexpected social networks which will shape tomorrow's Indonesians.
Valuing News: Aligning Individual, Institutional and Societal Perspectives. This project aims to identify the links between the preparedness of individuals to pay for news, the value of news brands and organisational cultures of news publishers, and the social value of news in promoting a democratic public sphere. Its significance arises with the ongoing crisis of news media business models, which is raising new questions about the future of journalism, and the changing role of governments worl ....Valuing News: Aligning Individual, Institutional and Societal Perspectives. This project aims to identify the links between the preparedness of individuals to pay for news, the value of news brands and organisational cultures of news publishers, and the social value of news in promoting a democratic public sphere. Its significance arises with the ongoing crisis of news media business models, which is raising new questions about the future of journalism, and the changing role of governments worldwide in financing news production. Its expected outcomes include advancing debates about how to support public interest journalism, and the value of news as both a commodity and a public good. It will be of benefit to industry, policymakers and the community in addressing the prospects for Australian journalism. Read moreRead less
Special Research Initiatives - Grant ID: SR0354500
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
- ....ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
-facilitate training in array methodologies and bioinformatics,
-co-ordinate innovation of technologies,-provide centralised data warehousing,
-provide access to automated high-level gene annotation,
-provide data mining tools,
-set standards for data management and exchangeRead moreRead less
Intercultural inquiry in a trans-national context: Exploring the legacy of the 1948 American-Australian Scientific Expedition to Arnhem Land. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal te ....Intercultural inquiry in a trans-national context: Exploring the legacy of the 1948 American-Australian Scientific Expedition to Arnhem Land. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US relationship at a formative historical moment.Read moreRead less
Expedition to Arnhem Land: Intercultural inquiry in a trans-national context. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US rel ....Expedition to Arnhem Land: Intercultural inquiry in a trans-national context. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US relationship at a formative historical moment.Read moreRead less