Clinical Implications Of IL7R Genotype: From Disease Risk To Disease Management
Funder
National Health and Medical Research Council
Funding Amount
$627,765.00
Summary
We’ve identified a genetic test (IL7R?) that may predict and prevent the risk of patients (i) failing to respond adequately to treatment for HIV (ii) who are at high risk of death after bone marrow transplantation and (iii) who fail to respond to interferon treatment for MS. This project aims to confirm these in very large patient groups and uncover the cellular basis for the genetic effect. Our goal is to provide a novel test that will improve patient outcomes in 3 serious disease states.