Epidemiological Investigation Of The Role Of Early Life Environment In The Development Of Immune Function And Allergic And Autoimmune Disease: Knowledge Generation For Future Primary Prevention.
Funder
National Health and Medical Research Council
Funding Amount
$664,584.00
Summary
Immune diseases, which include allergic and autoimmune diseases, are accounting for an increasing fraction of the disease burden in Australia. It is now increasingly recognised that early life changes to the immune system by environmental factors can impact on the risk of these diseases. The goal of this fellowship is the prevention of allergic and autoimmune disease.
Interfacing Epidemiology With Systems Biology For Disease Prevention
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Over recent time, allergic and some autoimmune diseases have increased among modern children. The change has been too rapid to be due to genetic factors alone and my research program examines also the role of the changing environment. It also examines the health effects of new man-made exposures like plastic product chemicals.
Environmental Risk Factors For Primary Progressive Multiple Sclerosis
Funder
National Health and Medical Research Council
Funding Amount
$86,118.00
Summary
Primary Progressive Multiple Sclerosis (PPMS) is a form of MS affecting 10% of people with the disease. PPMS has been less researched than the more common form of MS, Relapsing Remitting MS (RRMS), and unlike RRMS, there are currently no effective treatments. This project will examine whether the established risk factors for RRMS also hold for PPMS, whether the magnitude of risk associated with these factors is the same for PPMS, and whether novel risk factors for PPMS can be identified.
Sun Exposure, Vitamin D And Photohealth Over The Lifetime
Funder
National Health and Medical Research Council
Funding Amount
$622,655.00
Summary
Australia is a sunny country with a diverse population. Inappropriate sun exposure for skin type leads to skin cancer (mainly in the fair-skinned) and vitamin D deficiency (particularly in the darker-skinned). Potential benefits of sun exposure are broader than vitamin D production, but remain ill-defined. There are few data on appropriate sun exposure for children. This research fellowship builds the evidence to guide sun exposure messages.
Building Research Capacity In Epidemiological Studies Of Chronic Disease And Injury
Funder
National Health and Medical Research Council
Funding Amount
$451,716.00
Summary
My vision is to build further capacity in epidemiological research to generate findings that directly inform chronic disease and injury prevention strategies. I will do this by: 1. leading epidemiological research designed to better understand the role and modification of risk factors for chronic disease and injury; 2. developing statistical methodology and tools for the analysis of categorical outcome data that commonly arise in epidemiological studies.