Role Of The EHF Transcription Factor In Regulating The Differentiation Status Of Colon Cancers
Funder
National Health and Medical Research Council
Funding Amount
$621,950.00
Summary
New treatment strategies for colon cancer are urgently needed. This application will test a novel approach for treating colon cancer based on the re-induction of differentiation of colon cancer cells, by reactivating a gene called EHF. We expect this to reduce the propensity for colon cancer cells to spread to distant organs and to increase their sensitivity to chemotherpay. This has the potential to significantly benefit the clinical management of patients with this disease.