Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100030
Funder
Australian Research Council
Funding Amount
$270,000.00
Summary
Test-bed for Wide-Area Software Defined Networking Research. Test bed for wide-area software defined networking research: This project aims to develop a wide-area test bed, spanning ten organisations, for conducting research and experimentation in the emerging disruptive technology of Software Defined Networking (SDN). SDN is likely to bring long-term transformation to the networking industry, much like cloud computing did, by enabling dynamic virtualised elastic network services under software ....Test-bed for Wide-Area Software Defined Networking Research. Test bed for wide-area software defined networking research: This project aims to develop a wide-area test bed, spanning ten organisations, for conducting research and experimentation in the emerging disruptive technology of Software Defined Networking (SDN). SDN is likely to bring long-term transformation to the networking industry, much like cloud computing did, by enabling dynamic virtualised elastic network services under software control. The test bed will empower Australian researchers in network technologies and dependent applications (for example, multimedia and security) to collaboratively develop and demonstrate novel ideas at scale. This is expected to benefit Australia by giving our researchers international recognition in this nascent area, and developing a national talent pool for local industry.Read moreRead less
ARC Centre of Excellence for Ultrahigh Bandwidth Devices for Optical Systems. The Centre will take the next big step in optical systems by transforming photonic integrated circuits into a technology that will have a profound effect on economies and lifestyles around the world. This will enable the Internet to transfer vast amounts of data with significantly improved energy efficiency; it will lead to secure transmission using quantum photonics-based devices, and to the detection of mid-infrared ....ARC Centre of Excellence for Ultrahigh Bandwidth Devices for Optical Systems. The Centre will take the next big step in optical systems by transforming photonic integrated circuits into a technology that will have a profound effect on economies and lifestyles around the world. This will enable the Internet to transfer vast amounts of data with significantly improved energy efficiency; it will lead to secure transmission using quantum photonics-based devices, and to the detection of mid-infrared signatures of light from distant stars and complex molecules of environmental or biochemical importance. We will achieve this by developing new materials with optical properties to control light and engineering them into miniature photonic processors.Read moreRead less
Optimising throughput and Delay in network coded systems. This project addresses one main disadvantage of network coding: decoding delay. By solving this issue, we will unlock the true potential of network coding: delivery of high data rates in wireless and wireline networks. This will make network coding an attractive choice for live video streaming and mission-critical delay-sensitive applications.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100116
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
100 Gbit to 1 Terabit per second optical communication test bed facility. This facility will develop and demonstrate novel optical technologies that will underpin the generation and transmission of a higher-speed Ethernet at 100 Gb/s to 1Terabit/s, and will lead to better broadband and more energy efficient internet. At the foundation of this research will be a test bed with multiple signal sources at data rates above 50 Gbaud.
The Shape of Plants; Discovering factors that control morphology by organizing the cytoskeleton. Understanding how plants generate the huge diversity of shapes seen in nature is both a scientific challenge and a biotechnological opportunity. Microtubules dominate cell architecture, providing dynamic, yet rigid, frameworks for defining or changing growth polarity. We recently discovered and cloned MOR1, a gene that is essential for organizing microtubules and controlling morphogenesis. This place ....The Shape of Plants; Discovering factors that control morphology by organizing the cytoskeleton. Understanding how plants generate the huge diversity of shapes seen in nature is both a scientific challenge and a biotechnological opportunity. Microtubules dominate cell architecture, providing dynamic, yet rigid, frameworks for defining or changing growth polarity. We recently discovered and cloned MOR1, a gene that is essential for organizing microtubules and controlling morphogenesis. This places us in a strong position to resolve a long-standing mystery: how are microtubules organized? We intend to define MOR1's structural attributes, identify its interacting proteins and innovate an ambitious screen for additional genes that have related functions. This project should stimulate new ideas and applications.Read moreRead less
Investigating The Cellular Response To Iron-Depletion: The Trilogy Of ASK1, Thioredoxin And Ribonucleotide Reductase
Funder
National Health and Medical Research Council
Funding Amount
$552,572.00
Summary
Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for t ....Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453295
Funder
Australian Research Council
Funding Amount
$369,697.00
Summary
NMR cryosystem for structural and functional biology. State-of-the-art hardware is requested for the 600-MHz NMR spectrometers situated at University of Sydney and UNSW. A cryosystem installed at USyd. will provide a massive boost in productivity and will allow projects previously inaccessible due to excessive turn-around times, or sensitivity or solubility problems to become tractable. This system will provide new opportunities to researchers from USyd., UNSW and ANU, but will restrict the ver ....NMR cryosystem for structural and functional biology. State-of-the-art hardware is requested for the 600-MHz NMR spectrometers situated at University of Sydney and UNSW. A cryosystem installed at USyd. will provide a massive boost in productivity and will allow projects previously inaccessible due to excessive turn-around times, or sensitivity or solubility problems to become tractable. This system will provide new opportunities to researchers from USyd., UNSW and ANU, but will restrict the versatility of the USyd. instrument. The installation of a TBI probe at UNSW will counter this, and provide a REAL network of NMR instruments across NSW and the ACT.Read moreRead less
CesA (cellulose synthase) genes of Arabidopsis; all doing the same job or specialists cooperating to make the most abundant biopolymer. The biosphere makes more cellulose than any other polymer with fibre industries depending on its physical properties and atmospheric carbon dioxide levels depending on its stability as a carbon sink. Demonstrations that cellulose production needs CesA genes drove recent progress in elucidating the mechanism of synthesis. CesA proteins all look very similar but i ....CesA (cellulose synthase) genes of Arabidopsis; all doing the same job or specialists cooperating to make the most abundant biopolymer. The biosphere makes more cellulose than any other polymer with fibre industries depending on its physical properties and atmospheric carbon dioxide levels depending on its stability as a carbon sink. Demonstrations that cellulose production needs CesA genes drove recent progress in elucidating the mechanism of synthesis. CesA proteins all look very similar but if all do the same job, why do plants need so many and why do none seem redundant? We will make gene interchanges in transgenic plants, build chimeric genes and identify where each CesA protein operates. This will identify their individual and cooperative contributions to cellulose production.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989084
Funder
Australian Research Council
Funding Amount
$275,000.00
Summary
Confocal Laser Scanning Microscopy for Live Cell Imaging. The University of Newcastle has invested heavily in its biological and life sciences to create a research nexus focusing on national research priorities in biotechnology and environmental protection. The Live Cell Imaging platform will be utilized by scientists researching such strategically important areas including developmental biology, intracellular signalling cascades, cell cycle dynamics, plant development and microbiology. Moreover ....Confocal Laser Scanning Microscopy for Live Cell Imaging. The University of Newcastle has invested heavily in its biological and life sciences to create a research nexus focusing on national research priorities in biotechnology and environmental protection. The Live Cell Imaging platform will be utilized by scientists researching such strategically important areas including developmental biology, intracellular signalling cascades, cell cycle dynamics, plant development and microbiology. Moreover, this component of the University's research portfolio plays a major role in the postgraduate training of young Australian scientists who will, in turn, fuel future developments in both the life sciences and biotechnology industries.Read moreRead less
Role of a novel zinc-binding motif in the structure-function of deubiquitinating enzymes. The ubiquitin pathway destroys many proteins that control cell function and growth, by attaching ubiquitin to them and marking them for degradation. Deubiquitinating enzymes (DUBs) regulate protein destruction by controlling the amount of ubiquitin attached. DUBs and the ubiquitin pathway can also be manipulated in biotechnology applications. However, very little is known about the structure/function of DUB ....Role of a novel zinc-binding motif in the structure-function of deubiquitinating enzymes. The ubiquitin pathway destroys many proteins that control cell function and growth, by attaching ubiquitin to them and marking them for degradation. Deubiquitinating enzymes (DUBs) regulate protein destruction by controlling the amount of ubiquitin attached. DUBs and the ubiquitin pathway can also be manipulated in biotechnology applications. However, very little is known about the structure/function of DUBs. We have identified a new zinc-binding motif in DUBs, and we will explore how this contributes to their structure, and interactions with other proteins. This will significantly enhance our knowledge of how DUBs function in both biotechnology and in controlling cell function.Read moreRead less