Next generation high throughput lipidomics using adaptive modelling. This project aims to develop a unique high-throughput method to capture the lipidomic profile of human plasma suitable for large human population screening. Lipids are fundamental to every biological system, but our understanding of their regulation in humans have been largely superficial. By incorporating a new lipidomics approach, with genomic data, this project aims to expand our understanding of human biology by identifying ....Next generation high throughput lipidomics using adaptive modelling. This project aims to develop a unique high-throughput method to capture the lipidomic profile of human plasma suitable for large human population screening. Lipids are fundamental to every biological system, but our understanding of their regulation in humans have been largely superficial. By incorporating a new lipidomics approach, with genomic data, this project aims to expand our understanding of human biology by identifying regulators of lipid metabolism. The large diversity in humans necessitate sufficient sample sizes to identify true genetic regulators, but to date techniques capturing phenotypic data (lipids) have been largely limited. It is anticipated that this study will identify new regulators of lipid metabolism in humans.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100027
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates tha ....ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates that will innovate novel diagnostic technologies, enable data-driven decision platforms and address barriers to biosecurity adoption. This suite of graduates and technologies will transform the plant biosecurity sector to protect Australia’s $5.7 trillion natural and productive ecosystems.Read moreRead less
Linking terrestrial–aquatic fluxes to rectify the Australian carbon balance. This project aims to rectify the Australian carbon balance by determining the amount of terrestrial carbon that is lost to streams and rivers across the country. Through a novel integration of high-resolution hydrochemical and gas measurements, remote sensing and machine learning algorithms, the project intends to generate new knowledge about the links between terrestrial carbon sequestration and aquatic carbon export. ....Linking terrestrial–aquatic fluxes to rectify the Australian carbon balance. This project aims to rectify the Australian carbon balance by determining the amount of terrestrial carbon that is lost to streams and rivers across the country. Through a novel integration of high-resolution hydrochemical and gas measurements, remote sensing and machine learning algorithms, the project intends to generate new knowledge about the links between terrestrial carbon sequestration and aquatic carbon export. Expected outcomes include a refined estimate of the net carbon sequestration potential across Australian biomes and seasons. This should provide significant benefits such as avoiding misalignment of greenhouse gas abatement policies and advancing carbon cycling models and predictions.Read moreRead less
Implementing Indigenous knowledge approaches in doctoral education . This project aims to apply Indigenous knowledge approaches (agency of Country; power of stories and iterative, intergenerational and intercultural knowledge production) to Australian doctoral education. This project expects to generate new knowledge in the area of Indigenous and transcultural (migrant, refugee and international) doctoral education. Expected outcomes of the project include multimedia portal/app and policy recomm ....Implementing Indigenous knowledge approaches in doctoral education . This project aims to apply Indigenous knowledge approaches (agency of Country; power of stories and iterative, intergenerational and intercultural knowledge production) to Australian doctoral education. This project expects to generate new knowledge in the area of Indigenous and transcultural (migrant, refugee and international) doctoral education. Expected outcomes of the project include multimedia portal/app and policy recommendations for doctoral supervision, language and examination protocols that place Indigenous and transcultural knowledges at the forefront of Australian research. This should provide significant benefits to Australian higher education, enabling Australia to become a world leader in global knowledge production. Read moreRead less
About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock a ....About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock and its role in the normal biology of the heart. New data will significantly enhance our understanding of the biology of MR and cortisol for the circadian time keeping function in peripheral tissues, and gain a clearer understand how our heart cells adapt to environmental circadian disruptors such as shift work. Read moreRead less
Building An Indigenist Health Humanities Collective. This proposal aims to develop Indigenist Health Humanities as a new and innovative field of inquiry, building an intellectual collective capable of bridging the knowledge gap that hinders current efforts to close the gap in Indigenous health inequality. Bringing together health and the humanities through the particularity of Indigenous scholarship, a deeper understanding of the human experience of health will be developed alongside a greater u ....Building An Indigenist Health Humanities Collective. This proposal aims to develop Indigenist Health Humanities as a new and innovative field of inquiry, building an intellectual collective capable of bridging the knowledge gap that hinders current efforts to close the gap in Indigenous health inequality. Bringing together health and the humanities through the particularity of Indigenous scholarship, a deeper understanding of the human experience of health will be developed alongside a greater understanding of the enablers to building a transdisciplinary collective of Indigenous health researchers. The potential benefits include a more sustainable, relational and ethical approach to advancing new knowledge, advancing research careers and advancing health outcomes for Indigenous people. Read moreRead less
Developing Robust Small Area Population Forecasts for Planning and Policy. This project aims to create more robust, detailed, and accurate small area population forecasts, and implement them in a sophisticated forecasting system for one jurisdiction in Australia, USA, UK and Canada. The project is significant as it expects to generate a suite of new and innovative methods, theory, and population forecasts that will be useful to researchers and planners both in Australia and overseas. Expected ou ....Developing Robust Small Area Population Forecasts for Planning and Policy. This project aims to create more robust, detailed, and accurate small area population forecasts, and implement them in a sophisticated forecasting system for one jurisdiction in Australia, USA, UK and Canada. The project is significant as it expects to generate a suite of new and innovative methods, theory, and population forecasts that will be useful to researchers and planners both in Australia and overseas. Expected outcomes include new forecasting methods, associated computer code, many open-access academic papers, and new international collaborations. More detailed and reliable population forecasts will bring substantial benefits to those planning our future infrastructure requirements (e.g. schools, hospitals, housing and transport).
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Dating the aboriginal rock art sequence of the Kimberley in north west Australia. This project aims to develop a robust time scale for the known aboriginal rock art sequence in the Kimberley, Western Australia (WA). The project will use new knowledge of complex processes on sandstone surfaces across the north Kimberley, and an innovative combination of four scientific dating methods developed through our earlier work. The project expects to provide a well-dated sequence for Kimberley rock art ba ....Dating the aboriginal rock art sequence of the Kimberley in north west Australia. This project aims to develop a robust time scale for the known aboriginal rock art sequence in the Kimberley, Western Australia (WA). The project will use new knowledge of complex processes on sandstone surfaces across the north Kimberley, and an innovative combination of four scientific dating methods developed through our earlier work. The project expects to provide a well-dated sequence for Kimberley rock art based on replication of results, confirmation across different methods, and a large interdisciplinary data set. The project will allow rigorous analysis of the relationship between dating results and rock art styles that has not previously been possible, and give new insights into Australia’s deep indigenous heritage. This will have a significant impact for future efforts in rock art conservation, and lay a foundation for cultural tourism, with important benefits for the local economy and health of regional indigenous communities.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100015
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation ....ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation of infrastructure design in Australia and internationally. Achieving carbon neutral infrastructure in its whole life will bring significant far-reaching benefits, including equipping industry with tools required to meet Australia’s emission reduction targets as well as economic, commercial, environmental, and social gains.Read moreRead less
Deadly Start: Enabling Preschoolers’ Literacy, Numeracy and Wellbeing. This project aims to test the effectiveness of a new preschool oral language, literacy, numeracy and wellbeing intervention for Indigenous and non-Indigenous Australian students using powerful interdisciplinary approaches.
The project generates new knowledge about enabling preschool children to have a deadly start to literacy, numeracy and wellbeing, capitalising on research-derived interventions.
Expected outcomes include ....Deadly Start: Enabling Preschoolers’ Literacy, Numeracy and Wellbeing. This project aims to test the effectiveness of a new preschool oral language, literacy, numeracy and wellbeing intervention for Indigenous and non-Indigenous Australian students using powerful interdisciplinary approaches.
The project generates new knowledge about enabling preschool children to have a deadly start to literacy, numeracy and wellbeing, capitalising on research-derived interventions.
Expected outcomes include salient intervention and measures and advances in preschool education that enable a deadly start.
The benefits encompass identifying effective intervention and drivers that support a deadly start to literacy and numeracy, and having adaptive motivation, new theory and developmentally appropriate measures.Read moreRead less