I am a lab-based neurochemist-cell biologist with expertise in protein chemistry and pharmacology. My research focuses on the dynamin family of proteins in the endocytosis of synaptic vesicles and in the molecular mechanisms of synaptic transmission in th
I am a biochemist-pharmacologist determining how neurotransmitter transporters work, which will aid in the development in novel therapies for disorders of the nervous system
I am a molecular biologist interested in understanding how cells are able to actively kill themselves, and how cells make the decision to live or die. Understanding how cells kill themselves will ultimately lead to better therapies designed to kill cancer
I am a cancer biologist determining the mechanisms of anti-cancer drug action and drug resistance and performing preclinical studies to identify novel chemotherapeutic drug combinations for the treatment of cancer.
I am a cancer cell biologist investigating molecular mechanisms of leukaemia cell resistance to chemotherapeutic drugs, and novel strategies for the management of high risk or relapsed disease. For these purposes I have developed orthotopic xenograft mode
I am a molecular geneticist investigating the development of cancer, the mechanisms controlling apoptosis, and how impaired apoptosis contributes to tumorigenesis and the resistance of cancer cells to therapy.
Over a research career currently spanning 44 years, the single unifying theme of my research has been the regulation of steroid hormone biosynthesis. Since 1993, the focus of my laboratory has been oestrogen biosynthesis. We study three main areas: i) the