Bioengineered bioscaffolds for Achilles tendinopathy treatment. The purpose of the project is to improve outcomes following the surgical treatment of Achilles tendinopathy. The expected outcome is the development in animals of new ways to design tissue engineered bioscaffolds for the surgical repair of Achilles tendinopathy.
Developing a disability policy model to target the prevention or reduction of limitations on functioning and wellbeing. With the ageing of Australian society the challenge for public health is shifting from preventing death and disease onset to supporting healthy and productive ageing. The disability policy model will allow cost-effective targeting of interventions to reduce or prevent onset of disability or reduce its severity particularly among older Australians.
Global dementias: Examining structural vulnerability and dementia outcomes. This project aims to examine the social and cultural dimensions of dementia by using a comparative ethnographic approach to examine the experiences of people living with dementia in Australia, Malaysia and India. The project expects to generate new anthropological knowledge about structural inequalities by examining how dementia is responded to in diverse geographic, cultural and social settings. Expected outcomes of thi ....Global dementias: Examining structural vulnerability and dementia outcomes. This project aims to examine the social and cultural dimensions of dementia by using a comparative ethnographic approach to examine the experiences of people living with dementia in Australia, Malaysia and India. The project expects to generate new anthropological knowledge about structural inequalities by examining how dementia is responded to in diverse geographic, cultural and social settings. Expected outcomes of this project include the creation of a new evidence-base on dementia and the production of briefing documents to guide global health frameworks. The project should provide significant benefits for people living with dementia by providing locally-relevant strategies to respond to dementia and resultant disability.Read moreRead less
Machine Learning for Fracture Risk Assessment from Simple Radiography. This project aims to develop a novel, reliable, low-cost system to detect poor bone health and assess fracture risk to help to prevent and manage osteoporosis-related fractures. Currently, osteoporosis-related fractures cost our health system millions of dollars annually and costs are increasing with our ageing population. Early detection of poor bone health will improve the effectiveness of preventive measures and ease this ....Machine Learning for Fracture Risk Assessment from Simple Radiography. This project aims to develop a novel, reliable, low-cost system to detect poor bone health and assess fracture risk to help to prevent and manage osteoporosis-related fractures. Currently, osteoporosis-related fractures cost our health system millions of dollars annually and costs are increasing with our ageing population. Early detection of poor bone health will improve the effectiveness of preventive measures and ease this burden. Current methods include unreliable, crude clinical and visual guides that suggest osteoporosis screening. The project plans to develop a novel system by applying machine learning algorithms to radiology data which is commonly captured for diagnosing other conditions.Read moreRead less
Hospital Admission, Cerebral Palsy, Intellectual Disability And Birth Defects In Assisted Conception Infants.
Funder
National Health and Medical Research Council
Funding Amount
$115,110.00
Summary
We have recently completed a study examining the prevalence of birth defects in assisted conception infants born in Western Australia from 1993-1997. Contrary to reassuring claims by other researchers in this area, we found that assisted conception infants have a two-fold increased risk of being diagnosed with a major birth defect by one year of age. We now propose to examine other long-term health outcomes in these children. This study involves record linkage between the WA Reproductive Technol ....We have recently completed a study examining the prevalence of birth defects in assisted conception infants born in Western Australia from 1993-1997. Contrary to reassuring claims by other researchers in this area, we found that assisted conception infants have a two-fold increased risk of being diagnosed with a major birth defect by one year of age. We now propose to examine other long-term health outcomes in these children. This study involves record linkage between the WA Reproductive Technology Register and four other population-based databases. The prevalence of cerebral palsy, intellectual disability, hospital admission and birth defects in assisted conception children born in WA between 1993 and 2001 will be compared to that seen in all other Western Australian children born over the same time period. The collection of information on risks associated with assisted conception treatment is vital to allow adequate counselling of couples considering fertility treatment. Cerebral palsy, intellectual disability, birth defects and hospital admission are all serious adverse health outcomes and, despite the introduction of IVF to most Western countries twenty years ago, there are limited data in the literature concerning the occurrence of these conditions in assisted conception infants. Quantifying the contribution of assisted conception treatment to neonatal, infant and childhood morbidity and mortality is also important for the planning of health service provision. Although assisted conception births represent only a small proportion of total births in Australia, these infants may require a disproportionate level of health care services, such as neonatal intensive care treatment due to complications associated with preterm or multiple birth. The wide application of assisted conception treatment in Australia and the increased number of pregnancies achieved by these means reinforce the urgent need for valid data on the health of children born after these procedures.Read moreRead less
Outcomes of specialist disability housing for people with disability. This project aims to systematically investigate the experience, outcomes and economic impact of people with disability moving into specialist disability accommodation housing. Health, wellbeing, community participation, support outcomes and lived experience of people with disability will be measured before moving and over 2 years after they move. The project provides the opportunity to identify the personal, disability, housi ....Outcomes of specialist disability housing for people with disability. This project aims to systematically investigate the experience, outcomes and economic impact of people with disability moving into specialist disability accommodation housing. Health, wellbeing, community participation, support outcomes and lived experience of people with disability will be measured before moving and over 2 years after they move. The project provides the opportunity to identify the personal, disability, housing and support factors that shape outcomes for people with disability. The intended outcome is comprehensive knowledge that can inform policy, build evidence across housing, technology, support and disability sectors and ultimately benefit people with disability by generating innovative practice in housing and support.Read moreRead less
Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability hav ....Quality and outcomes of individual supported living arrangements for adults with intellectual and developmental disabilities. This project identifies service quality aspects contributing to positive outcomes in individual supported living arrangements that enable adults with developmental disabilities to live in their own homes. 150 arrangements will be evaluated across Western Australia, New South Wales and Victoria, providing evidence of service quality in support of people with disability having choice and control in their living arrangements.Read moreRead less
An Australasian, Multi-centre, Randomized, Double-blind, Placebo-controlled Trial Of The Efficacy Of Fluoxetine In Improving Functional Recovery After Acute Stroke
Funder
National Health and Medical Research Council
Funding Amount
$2,306,367.00
Summary
Stroke is one of the top three causes of disability. Treatments that improve recovery after stroke are lacking. We reviewed the world literature and found a number of very small studies which, together, suggest that the antidepressant drug, fluoxetine, may improve the recovery in stroke patients. AFFINITY is a large trial in 1600 Australians and New Zealanders with stroke which aims to find out whether taking fluoxetine for 6 months after a stroke improves recovery compared to a placebo.
Participation versus performance: managing (dis)ability, gender and cultural diversity in junior sport. Playing sport can benefit young people but by its nature is competitive. This project will examine how well, if at all, junior sports clubs manage a need to be successful alongside providing an inclusive environment welcoming people of all backgrounds and abilities.
Population-based Data Linkage To Investigate The Health And Development Of Children Born After IVF
Funder
National Health and Medical Research Council
Funding Amount
$321,972.00
Summary
In Australia 1 in 25 births are conceived from IVF treatment and this is increasing. My research program will use a comprehensive set of linked population data to address key questions in the IVF field following major changes to IVF practice in the last decade. This research (examining fetal growth, birth defects, intellectual disability and school achievement) has the potential to influence clinical practice and will greatly improve the information available for pre-treatment counselling.