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Long-term Effects Of A Very Low Carbohydrate, Low Saturated Fat Diet Compared To A Conventional High Carbohydrate, Low Fat Diet On Glycemic Control And Cardiovascular Disease Risk In Overweight And Obese Patients With Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$1,311,890.00
Summary
This project is a clinical study investigating whether an very low carbohydrate, low saturated fat diet provides greater benefits for improving blood glucose control and cardiovascular health compared to a conventional, currently prescribed low fat, high unrefined carbohydrate diet in obese patients with type 2 diabetes. This information will provide the highest quality evidence on which the NHMRC can make dietary recommendations for the optimal management of diabetes.
Providing Evidence For The Primary Prevention Of The High-prevalence Mental Disorders In Men: The Role Of Diet In The Aetiology Of Depression, Anxiety, And Psychological Distress
Funder
National Health and Medical Research Council
Funding Amount
$300,862.00
Summary
Depression is predicted to become the second-most common cause of disability in the world by 2020, despite the increased energy devoted to recognition and treatment. This study will examine the association between diet quality and depressive and anxiety disorders in men, to identify to what extent diet quality is related to the risk for and/or course of these illnesses.
Dietary And Lifestyle Advice And Treatment For Women With Borderline Gestational Diabetes: The IDEAL Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$661,140.00
Summary
Over 22,000 pregnant women in Australia each year (7.7% of pregnancies) develop Borderline Gestational Diabetes Mellitus (GDM). The IDEAL Trial is assessing whether implementing dietary and lifestyle advice and monitoring blood glucose in women with Borderline GDM is effective in reducing the risk of serious health outcomes for women and infants. If treatment of these women is effective this would reduce the burden of disease for women and their babies, with implications for improved health thro ....Over 22,000 pregnant women in Australia each year (7.7% of pregnancies) develop Borderline Gestational Diabetes Mellitus (GDM). The IDEAL Trial is assessing whether implementing dietary and lifestyle advice and monitoring blood glucose in women with Borderline GDM is effective in reducing the risk of serious health outcomes for women and infants. If treatment of these women is effective this would reduce the burden of disease for women and their babies, with implications for improved health through childhood, adolescence and adulthood.Read moreRead less
Reducing consumption of sugary drinks (or sugar-sweetened beverages) would improve the healthiness of young Australians’ diets. Young Australians drink sugary drinks in high quantities, and they contribute a lot of ‘empty calories’ to the diet. They are also known to cause tooth decay, obesity and diabetes. This study will test the effectiveness of consumer information/warning labels on drink containers in reducing the purchase of SSBs.
Identifying Why Some People Consume Excess Dietary Fat. A Twin Study
Funder
National Health and Medical Research Council
Funding Amount
$365,462.00
Summary
Obesity is a significant public health problem, yet some individuals are less susceptible to the development of obesity. High fat eating patterns are commonly associated with overweight/obesity. The taste system is the gatekeeper of digestion and the sense of taste responds to fat, and that the fat taste response is associated with obesity. Using twins as subjects to disentangle the influences of 'nature and nuture', in this project we will identify the mechanisms responsible for linking fat tas ....Obesity is a significant public health problem, yet some individuals are less susceptible to the development of obesity. High fat eating patterns are commonly associated with overweight/obesity. The taste system is the gatekeeper of digestion and the sense of taste responds to fat, and that the fat taste response is associated with obesity. Using twins as subjects to disentangle the influences of 'nature and nuture', in this project we will identify the mechanisms responsible for linking fat taste response to development of obesity.Read moreRead less
Dietary Modulation Of Maternal Gut Flora With Oligosaccharides In Pregnancy As A Novel Allergy Prevention Strategy
Funder
National Health and Medical Research Council
Funding Amount
$1,681,512.00
Summary
Declining intake of dietary fibre is a major factor implicated in the changing profile of healthy gut bacteria, and the associated increase in many inflammatory diseases including childhood allergy. This clinical trial aims to confirm findings in animal studies that increased dietary fibre in pregnancy can prevent allergy in the offspring, by favourably influencing metabolism and immune function during pregnancy.
The Effectiveness Of Motivational Enhancement Therapy For Obese Patients And Support Partners
Funder
National Health and Medical Research Council
Funding Amount
$547,644.00
Summary
Tbe obesity pandemic has been described by leading researchers as a problem out of control, with lifestyle interventions generally resulting in regain of treatment-induced weight losses. The present study will evaluate the effectiveness of motivational enhancement therapy (MET) for both patients and their support partners in helping obese patients to achieve long-term weight losses by sustaining their motivation for making difficult lifestyle changes over time.
Overcoming Barriers To Improved Physical Health In People With Severe Mental Illness
Funder
National Health and Medical Research Council
Funding Amount
$864,658.00
Summary
People with severe mental illness have high rates of cardiometabolic disease and reduced life-expectancy. Public intervention campaigns have had little impact on component risks (obesity, smoking, physical inactivity, poor nutrition). This study will determine factors associated with changes in cardiometabolic profiles in people with severe mental illness; examine impediments to risk modification; and develop targeted interventions for implementation within mental health services.
The Ovarian Cancer Prognosis And Lifestyle (OPAL) Study: Long-term Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$871,657.00
Summary
Ovarian cancer affects 1500 women each year in Australia and 5-year survival is <45%. Affected women thus face a poor prognosis and often ask what they can do to improve this. There is no direct evidence whether a woman’s lifestyle might influence her outcomes, although data from breast cancer suggest this is possible. The OPAL Study is following 960 women with ovarian cancer to identify whether lifestyle is associated with long-term survival to provide evidence for women with this disease.
The Older Australian Twins Study (OATS) Of Healthy Brain Ageing And Age-related Neurocognitive Disorders
Funder
National Health and Medical Research Council
Funding Amount
$940,960.00
Summary
Ageing is associated with cognitive decline and dementia. It is still not completely understood what relative contributions genes and environment play in these. This project is an extension of the Older Australian Twins Study to examine genetic and environmental factors associated with late life brain changes and dementia, and will establish an internationally significant cohort for novel discovery.