Discovery Early Career Researcher Award - Grant ID: DE230100197
Funder
Australian Research Council
Funding Amount
$438,000.00
Summary
In one zeptosecond: quantifying energy dissipation in heavy element fusion. This project aims to understand the process of energy dissipation in superheavy element fusion reactions. Using state-of-the art facilities unique to Australia, the first detailed measurements of the crucial early stages of these reactions will be made. This is expected to generate significant fundamental knowledge on why some superheavy element fusion reactions succeed, and why others fail. The outcomes are expected to ....In one zeptosecond: quantifying energy dissipation in heavy element fusion. This project aims to understand the process of energy dissipation in superheavy element fusion reactions. Using state-of-the art facilities unique to Australia, the first detailed measurements of the crucial early stages of these reactions will be made. This is expected to generate significant fundamental knowledge on why some superheavy element fusion reactions succeed, and why others fail. The outcomes are expected to significantly advance the fundamental understanding of nuclear reactions, and provide key guidance to international opportunities to create new superheavy elements and isotopes. Expected benefits include improving cancer treatments, understanding element abundance in the universe and improved safety in nuclear technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101565
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodol ....Flexible data modelling via skew mixture models:challenges and applications. This project seeks to explore new models for handling data with non-normal features. Parametric distributions are fundamental to statistical modelling and inference. For centuries, the ‘normal’ distribution has been the dominant model for continuous data. However, real data rarely satisfy the assumption of normality. There is thus a strong demand for more flexible distributions. This project aims to develop new methodologies in finite mixture modelling using skew component distributions to provide better models for handling data with non-normal features (such as skewness, heavy/light tails, and multimodality). Applications may include security intrusion detection, clinical diagnosis and prognosis, and flow and mass cytometry.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100755
Funder
Australian Research Council
Funding Amount
$462,948.00
Summary
Developing phytosystems for the biofiltration of air pollutants . This project aims to develop, evaluate and apply a range of biotechnology driven solutions for the use of phytosystem biofilters designed for air purification. The findings of the project will demonstrate the fundamental mechanisms behind botanical air pollutant biofiltration, apply systematic technological development against a range of air pollutants, and provide strategies to deploy the technology. With a transdisciplinary appr ....Developing phytosystems for the biofiltration of air pollutants . This project aims to develop, evaluate and apply a range of biotechnology driven solutions for the use of phytosystem biofilters designed for air purification. The findings of the project will demonstrate the fundamental mechanisms behind botanical air pollutant biofiltration, apply systematic technological development against a range of air pollutants, and provide strategies to deploy the technology. With a transdisciplinary approach utilising techniques new to this discipline, the project will substantially advance the fundamental science underlying this novel and highly valuable area of air-bioremediation technology, and will create a much stronger economic driver for this Australia-led innovation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240101090
Funder
Australian Research Council
Funding Amount
$433,217.00
Summary
In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite ....In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite growth is affected by different surface modifications on the commercial graphite electrodes. The success of the project will lead to a fundamental understanding of the lithium dendrite formation mechanism, enabling the construction of significantly safer batteries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100068
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This pr ....Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This project aims to harness cells’ exquisite biological properties to improve current detection techniques. It will integrate liposome-based sensors with microfluidics to perform analytical tasks ranging from food safety to diagnostics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101005
Funder
Australian Research Council
Funding Amount
$378,288.00
Summary
Miniaturised fibre-optic probes for biomedical image and sensor data fusion. The project aims to develop new types of tiny biomedical imaging devices based on optical fibres that can be inserted into the body via hypodermic needles or catheters. These devices will have the ability to generate a three-dimensional image of the tissue region. As the devices will also be able to sense biochemical or mechanical properties of the tissue, they can be used to differentiate healthy from diseased tissue. ....Miniaturised fibre-optic probes for biomedical image and sensor data fusion. The project aims to develop new types of tiny biomedical imaging devices based on optical fibres that can be inserted into the body via hypodermic needles or catheters. These devices will have the ability to generate a three-dimensional image of the tissue region. As the devices will also be able to sense biochemical or mechanical properties of the tissue, they can be used to differentiate healthy from diseased tissue. These minimally invasive devices will produce information-rich multidimensional fused image and sensor data, opening up new possibilities for biologists and medical researchers to study disease progression and treatment in living animals and humans, with great potential for scientific discovery.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100784
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
Breaking through the barrier: a new approach to understanding quantum tunneling in nuclear fusion. Experiments have shown major failings of our best predictive model of nuclear fusion. This project will address these failings through a multifaceted research program which will develop and benchmark an enhanced quantum model and test for missing physics by conducting precision fusion measurements for carefully chosen reactions. This project will develop a new technique that exploits fission follow ....Breaking through the barrier: a new approach to understanding quantum tunneling in nuclear fusion. Experiments have shown major failings of our best predictive model of nuclear fusion. This project will address these failings through a multifaceted research program which will develop and benchmark an enhanced quantum model and test for missing physics by conducting precision fusion measurements for carefully chosen reactions. This project will develop a new technique that exploits fission following fusion to directly probe physical processes inside the fusion barrier, which are missing from current models. This integrated approach to fusion will allow us to better predict fusion cross sections, create new elements and exploit radioactive ion beams at new international facilities.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100564
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Vascularized tumour models to elucidate the delivery of nanomedicine agents. This inter-disciplinary project aims to develop advances in in vitro models aimed at elucidating the delivery and transport of diagnostic and therapeutic nanomedicine agents in tumour tissues. The project aims to build on advanced tissue engineering principles and state-of-the-art micro-fabrication technologies to remove the limitation associated with animal studies and provide unprecedented mechanistic insights into th ....Vascularized tumour models to elucidate the delivery of nanomedicine agents. This inter-disciplinary project aims to develop advances in in vitro models aimed at elucidating the delivery and transport of diagnostic and therapeutic nanomedicine agents in tumour tissues. The project aims to build on advanced tissue engineering principles and state-of-the-art micro-fabrication technologies to remove the limitation associated with animal studies and provide unprecedented mechanistic insights into the delivery, transport and binding of nanomedicines into tumour tissues.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101222
Funder
Australian Research Council
Funding Amount
$371,392.00
Summary
The development of novel magnetic resonance imaging methods to investigate brain structure and function. Magnetic resonance imaging (MRI) is a non-invasive method that has revolutionised neuroscience. The goal of this project is to develop state-of-the-art MRI analysis methods that reveal new information about brain structure and function. These novel neuroimaging tools will be instrumental in furthering our understanding of how the brain works.
Discovery Early Career Researcher Award - Grant ID: DE220100846
Funder
Australian Research Council
Funding Amount
$418,388.00
Summary
Ordering photon energy carriers for efficient upconversion. This project aims to tackle the major challenge of upconversion nanosystems – their brightness. It will centre on building a donor/acceptor-ordered nanosystem to improve the energy transfer efficiency in hybrid nanomaterials. This ordered system will significantly improve the brightness of hybrid nanoparticles at low irradiance. Expected outcomes include a fundamental understanding of energy transfer mechanisms at sub-nm scales and a ne ....Ordering photon energy carriers for efficient upconversion. This project aims to tackle the major challenge of upconversion nanosystems – their brightness. It will centre on building a donor/acceptor-ordered nanosystem to improve the energy transfer efficiency in hybrid nanomaterials. This ordered system will significantly improve the brightness of hybrid nanoparticles at low irradiance. Expected outcomes include a fundamental understanding of energy transfer mechanisms at sub-nm scales and a new strategy to brighten the upconversion nanomaterials. This project should push upconversion nanoscience to a new generation and provide significant benefits in ultra-sensitive biomolecular assays and in vivo bioimaging.Read moreRead less