Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560680
Funder
Australian Research Council
Funding Amount
$901,862.00
Summary
Vibrational Spectroscopy Microprobe/FESEM/AFM Imaging of Cells, Tissues and Materials. State-of-the-art vibrational mapping and imaging equipment (integrated with a field-emission scanning electron microscope (FESEM) and an atomic force microscope (AFM)) will provide enabling technologies for cutting-edge research in disease diagnosis, identification of pathogens, mapping of the entry and distribution of pharmaceutics into cells, and materials research. An InVia Renishaw Raman spectrometer (sub ....Vibrational Spectroscopy Microprobe/FESEM/AFM Imaging of Cells, Tissues and Materials. State-of-the-art vibrational mapping and imaging equipment (integrated with a field-emission scanning electron microscope (FESEM) and an atomic force microscope (AFM)) will provide enabling technologies for cutting-edge research in disease diagnosis, identification of pathogens, mapping of the entry and distribution of pharmaceutics into cells, and materials research. An InVia Renishaw Raman spectrometer (sub-micron spatial positioning and micron spatial resolution) will be interfaced to an FEI Quanta FESEM for combined Raman (spectroscopic), EDS and SEM (morphological) imaging/mapping at the sub-cellular level. Complementary new-generation Raman and IR spectrometer upgrades will provide an integrated world-class equipment platform.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668403
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Enhanced micro-Raman and Fluorescence spectroscopy and imaging facility for biosystems and materials. The state-of-the-art spectroscopic and fluorescence imaging equipment will provide cutting-edge capabilities for fundamental and applied research with the potential to impact on improved health outcomes, pharmaceutics, biotechnology and nanomaterials research. Chemical probes based on molecular vibrations and fluorescence will allow changes in biomolecular composition within cells and tissues to ....Enhanced micro-Raman and Fluorescence spectroscopy and imaging facility for biosystems and materials. The state-of-the-art spectroscopic and fluorescence imaging equipment will provide cutting-edge capabilities for fundamental and applied research with the potential to impact on improved health outcomes, pharmaceutics, biotechnology and nanomaterials research. Chemical probes based on molecular vibrations and fluorescence will allow changes in biomolecular composition within cells and tissues to be mapped/imaged down to nanometre spatial resolution. This will provide new techniques for the diagnosis of diseases, e.g. cancer, the rapid identification of pathogens, the understanding and design of new drugs, and a range of biotechnology, nanomaterials and nanotechnology applications.Read moreRead less
Molecular characterization of stem cell differentiation and oocyte maturation using synchrotron infrared spectroscopy and Atomic Force Microscopy/Raman imaging. There are currently no molecular based methods to assess oocyte maturation and stem cell differentiation at the single cell level. Consequently the need for such techniques is critical in placing Australia at the forefront in this rapidly expanding field. Such technology would give Australia a leading edge in stem cell and oocyte researc ....Molecular characterization of stem cell differentiation and oocyte maturation using synchrotron infrared spectroscopy and Atomic Force Microscopy/Raman imaging. There are currently no molecular based methods to assess oocyte maturation and stem cell differentiation at the single cell level. Consequently the need for such techniques is critical in placing Australia at the forefront in this rapidly expanding field. Such technology would give Australia a leading edge in stem cell and oocyte research and ultimately assist in discovering disease cures for debilitating neurodegenerative diseases and spinal chord injury, while techniques for determining the viability of oocytes may have important implications for future in vitro fertilization programs. The intellectual property and technologies developed from this research could also have potential to impact on the global market.Read moreRead less