MicroRNA Expression Profiling Of Eutopic Endometrium In Women With Versus Without Endometriosis
Funder
National Health and Medical Research Council
Funding Amount
$224,211.00
Summary
Endometriosis is a medical condition where endometrium grows outside the womb. About 10% of women have this condition that can cause abdominal pain, painful periods and difficulty conceiving a child. Now endometriosis can only be diagnosed by surgical procedure. We believe that the presence of endometriosis causes particular small molecules called microRNAs to be present in the lining of the womb or in the blood only in women with endometriosis, and we could develop a test for endometriosis with ....Endometriosis is a medical condition where endometrium grows outside the womb. About 10% of women have this condition that can cause abdominal pain, painful periods and difficulty conceiving a child. Now endometriosis can only be diagnosed by surgical procedure. We believe that the presence of endometriosis causes particular small molecules called microRNAs to be present in the lining of the womb or in the blood only in women with endometriosis, and we could develop a test for endometriosis without resorting to surgery.Read moreRead less
Photonic Crystals For Probing Enzyme Activity: Single Cells Vs Bulk Measurements
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
We are all unique and we are unique down to a single cell. Can we understand the behaviour of a single cell? A novel biosensing platform will be developed to detect biological activity of single cells by simple measurement of a colour change. Successful fabrication of this biosensor will aid in the development of diagnostic devices for predictive and preventive medicine.
Tackling Urgent Antimicrobial Resistance Threats In Australia—in Action
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Antimicrobial resistance is a major global concern, there are limited new treatment options and current resistance surveillance practices have limitations. As a part of this fellowship I will collaborate with industry partners, utilise geographical mapping and novel DNA sequencing technologies with a view to enhance resistance surveillance for gonorrhoea and other public health threats, inform new treatment strategies and better understand the spread of gonorrhoea in the population.
The MetaFIND (Metagenomics For INfectious Diseases) Project: Developing Clinical Metagenomics To Improve The Healthcare Of Patients With Infections
Funder
National Health and Medical Research Council
Funding Amount
$303,014.00
Summary
The MetaFIND (Metagenomics For INfectious Diseases) project is a combined laboratory and clinical study that aims to develop and investigate the use of cutting-edge genome sequencing technology to improve the healthcare of patients with severe infections. It involves developing and optimising a method to determine the cause of an infection by analysing all the DNA present in a clinical sample – a promising “one-stop-shop” test to help improve diagnosis and subsequent treatment of infections.
Although medical tests and procedures can save lives, sometimes too much medical intervention can be harmful. In low back pain, for example, high numbers of X-ray, CT and MRI scans are provided unnecessarily. There is good evidence that imaging scans for low back pain can cause more harm than good. At the same time, people can miss out on treatments that we know to be effective. This fellowship will enable me to discover ways to ensure people receive the right care for low back pain.