My research activity is focused on the application of metabolomics to understand the role of lysosomes in health and disease. I have a major interest in understanding the molecular mechanisms of pathology resulting from lysosomal dysfunction. The outcomes
I am a biochemical geneticist working on the genetics and pathogenesis of mitochondrial energy generation disorders. I have a particular focus on the severe mitochondrial diseases of childhood but am also studying mitochondrial involvement in common disor
I am an applied respiratory physiologist investigating the pathophysiology of upper airway dysfunction in individuals with sleep-disordered breathing and the application of exercise physiology principles to the development of novel rehabilitation methods