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The Genetic Study Of Diabetic Retinopathy Risk In Type 1 Diabetes Mellitus
Funder
National Health and Medical Research Council
Funding Amount
$32,628.00
Summary
Type 1 diabetes is a disorder leading to high blood sugars, which can damage the small blood vessels of the the back of the eye and potentially lead to blindness. However not all diabetics will develop blinding eye disease. Our project aims to find the genes that contribute to the development of blinding diabetic eye disease so that patients who carry the genes can be managed and treated appropriately. This will help to reduce the incidence of blindness related to diabetic eye disease.
Identifying The Barriers To Optimal Diabetes And Diabetic Retinopathy Care In Non-English Speaking Adults With Type I And II Diabetes
Funder
National Health and Medical Research Council
Summary
Diabetes is a growing epidemic, with diabetic retinopathy being one of its common complications. With an ageing population, the public health and economic impact associated with diabetes are expected to magnify. Among the risk factors for sub-optimal diabetes care, language proficiency and cultural differences have been indicated. However, there is little to no research into the barriers of diabetes care in Australia�s non-English speaking population, which is the purpose of the proposed study.
Investigating The Mechanisms Underpinning The Dynamic Vessel Response In People With Diabetic Retinopathy
Funder
National Health and Medical Research Council
Funding Amount
$18,808.00
Summary
Endothelial dysfunction has been well-hypothesised as one of the key players in the pathogenesis of DR. However, there is strong evidence suggesting a neurovascular coupling mechanism in the retinal circulation during flicker. It is therefore unclear whether reduced flicker light induced vasodilation observed in diabetes and DR is associated with endothelial dysfunction, an impairment of neurovascular coupling or both. This project aims to address this important knowledge gap.
A Telephone And SMS Intervention To Promote Screening For Diabetic Retinopathy In People With Diabetes In Australia
Funder
National Health and Medical Research Council
Funding Amount
$28,796.00
Summary
One in two people with diabetes in Australia do not receive adequate screening or follow-up for diabetic retinopathy, a leading complication of diabetes and cause of vision loss and blindness. To tackle this issue, a new Australian study will evaluate a new telephone intervention designed to inform people with diabetes about diabetic retinopathy screening. This intervention is expected to improve future adherence to national screening guidelines for diabetic retinopathy.
Microvascular Complications Of Diabetes - Potential Role Of Regenerative Therapies
Funder
National Health and Medical Research Council
Funding Amount
$32,003.00
Summary
The global burden of diabetes is projected to reach more than 366 million by 2025. According to the AusDiab 2005 study, each year 0.8% of Australians develop diabetes. Diabetes is the leading cause of end-stage kidney disease in Australia. Current treatments slow damage to the kidney, but do not reverse kidney damage. We will explore the potential for adult progenitor cells (endothelial progenitor cells) to reverse damage to the kidney and restore its function.