Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of childr ....Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of children with ASD. The project intends to longitudinally explore the mechanisms of sibling impact in families with and without a child with ASD. The outcomes will deepen understanding of child development, providing an evidence base for effective interventions to increase child competence and aiming ultimately to reduce the social costs of ASD.Read moreRead less
Improving academic outcomes by moderating anxiety in children with autism. The project aims to investigate links between anxiety and academic enablers for children with autism. As a group, these children are currently achieving at lower rates than their peers, with implications for their future social and economic wellbeing. Effective interventions to improve educational outcomes are lacking. This project will investigate how anxiety, a commonly occurring condition in autism, impacts attitudes a ....Improving academic outcomes by moderating anxiety in children with autism. The project aims to investigate links between anxiety and academic enablers for children with autism. As a group, these children are currently achieving at lower rates than their peers, with implications for their future social and economic wellbeing. Effective interventions to improve educational outcomes are lacking. This project will investigate how anxiety, a commonly occurring condition in autism, impacts attitudes and behaviours that facilitate students’ participation in and ability to benefit from academic instruction in the classroom. Findings are intended to provide an evidence base for the development of an intervention suitable for use by service providers to increase academic achievement in children with autism.Read moreRead less
Normalising Ability Diversity through Career Transitions:Disability at Work. This project aims to investigate how the higher education sector can better support people with disabilities to transition from economic exclusion to work. One in five Australians have a disability and of these 47.3% are not employed. This is a significant issue with regulatory failures and challenges often affecting rights to education and work being exercised on an equal basis. This project seeks to examine internatio ....Normalising Ability Diversity through Career Transitions:Disability at Work. This project aims to investigate how the higher education sector can better support people with disabilities to transition from economic exclusion to work. One in five Australians have a disability and of these 47.3% are not employed. This is a significant issue with regulatory failures and challenges often affecting rights to education and work being exercised on an equal basis. This project seeks to examine international legal norms, theories and strategic and operational practices in the higher education sector. Expected outcomes include advances in scholarship on ableism, informed policy reform, and transferable operational processes for the education and employment sectors, to improve the transition of people with disabilities to work.Read moreRead less
Every Day Matters: Reducing School Non-Attendance in Autistic Students. Autistic children miss one day a week of school, three times more than their peers. This significantly impacts their learning, wellbeing and later, their vocational outcomes. This project aims to identify the factors that put autistic children at increased risk of missing school and map the supports and interventions used to reduce school non-attendance. Expected outcomes include an autism-specific model of the how and why s ....Every Day Matters: Reducing School Non-Attendance in Autistic Students. Autistic children miss one day a week of school, three times more than their peers. This significantly impacts their learning, wellbeing and later, their vocational outcomes. This project aims to identify the factors that put autistic children at increased risk of missing school and map the supports and interventions used to reduce school non-attendance. Expected outcomes include an autism-specific model of the how and why school non-attendance is elevated for autistic students. It is anticipated that this model make the important step of enabling teachers and professionals to identify which autistic children are most at risk of absenteeism and select the best strategies to support a positive and beneficial return to school.Read moreRead less
Outcomes of specialist disability housing for people with disability. This project aims to systematically investigate the experience, outcomes and economic impact of people with disability moving into specialist disability accommodation housing. Health, wellbeing, community participation, support outcomes and lived experience of people with disability will be measured before moving and over 2 years after they move. The project provides the opportunity to identify the personal, disability, housi ....Outcomes of specialist disability housing for people with disability. This project aims to systematically investigate the experience, outcomes and economic impact of people with disability moving into specialist disability accommodation housing. Health, wellbeing, community participation, support outcomes and lived experience of people with disability will be measured before moving and over 2 years after they move. The project provides the opportunity to identify the personal, disability, housing and support factors that shape outcomes for people with disability. The intended outcome is comprehensive knowledge that can inform policy, build evidence across housing, technology, support and disability sectors and ultimately benefit people with disability by generating innovative practice in housing and support.Read moreRead less
Mobile DNA activity in the mammalian primordial germline. Early in pregnancy, a handful of cells in the embryo become primordial germ cells (PGCs). These PGCs will eventually give rise to sperm or egg cells, representing a critical inter-generational genetic link. Mobile DNA sequences target PGCs to create new heritable genetic changes. This proposal aims to analyse the activity, regulation, and consequences of mobile DNA activity in PGCs. This project expects to generate significant knowledge a ....Mobile DNA activity in the mammalian primordial germline. Early in pregnancy, a handful of cells in the embryo become primordial germ cells (PGCs). These PGCs will eventually give rise to sperm or egg cells, representing a critical inter-generational genetic link. Mobile DNA sequences target PGCs to create new heritable genetic changes. This proposal aims to analyse the activity, regulation, and consequences of mobile DNA activity in PGCs. This project expects to generate significant knowledge about the origins of mammalian genetic diversity. Expected outcomes include enhanced national and international collaborations across disciplines and new experimental systems. The expected benefit is an enhanced understanding of the mutational processes underlying genetic diversity and disease in mammals.Read moreRead less
Determining principles for successful episode retrieval of repeated events. This project aims to develop the first-ever set of explanatory principles for how people successfully retain and retrieve individual episode memories from repeated experiences (e.g., one occurrence of a routine social encounter or job-related activity). By deepening our understanding of how memory works, this new knowledge is expected to lay the foundation for interview guidance and ongoing research aimed at enhancing th ....Determining principles for successful episode retrieval of repeated events. This project aims to develop the first-ever set of explanatory principles for how people successfully retain and retrieve individual episode memories from repeated experiences (e.g., one occurrence of a routine social encounter or job-related activity). By deepening our understanding of how memory works, this new knowledge is expected to lay the foundation for interview guidance and ongoing research aimed at enhancing the proficiency of investigations into matters that rely on detailed and accurate accounts of specific episodes. This includes workplace or traffic accident investigations, infectious disease contact tracing, as well as prosecution of repeated sexual offences.Read moreRead less
Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their ....Greater inclusion of people with disability in Australian workplaces. This project aims to develop a model of successful employment for people with a disability, identify sources of employer diversity that explain willingness to hire, and develop social marketing messages that improve employer attitudes and achieve greater inclusion in Australian workplaces. Workforce participation of people with a disability remains low. The outcome of this study will be more people with a disability and their carers gaining meaningful employment, with benefits including improved physical and mental health, social connections and economic security. It will benefit employers by creating more diverse workplaces and a broader talent pool, resulting in greater innovation and productivity.Read moreRead less
Foundations of a good egg: correctly transitioning from mitosis to meiosis. Production of viable offspring is essential to the survival of any species. In all sexually reproducing species, this requires a unique cell type, the germ cell. Germ cells undergo a special type of cell division, called meiosis, so that they can eventually produce gametes (sperm in males and eggs in females). This project aims to discover how germ cells halt the standard form of cell division, called mitosis, and initia ....Foundations of a good egg: correctly transitioning from mitosis to meiosis. Production of viable offspring is essential to the survival of any species. In all sexually reproducing species, this requires a unique cell type, the germ cell. Germ cells undergo a special type of cell division, called meiosis, so that they can eventually produce gametes (sperm in males and eggs in females). This project aims to discover how germ cells halt the standard form of cell division, called mitosis, and initiate meiotic division instead. It is important to understand all the fundamental processes that occur during normal germ cell development so that, in the future, we can use this knowledge to support agricultural advances, rescue endangered species and solve human problems such as infertility and genetic disease.Read moreRead less
Mechanisms that control the inheritance of mitochondrial DNA mutations. How do humans and other organisms prevent the accumulation of dangerous mitochondrial genome (mtDNA) mutations across generations? This Project aims to uncover the cellular and molecular pathways that help prevent the inheritance of mtDNA mutations to offspring by employing cutting-edge genetic technologies that the laboratory has recently developed in the germline of an animal model system. This Project will generate new kn ....Mechanisms that control the inheritance of mitochondrial DNA mutations. How do humans and other organisms prevent the accumulation of dangerous mitochondrial genome (mtDNA) mutations across generations? This Project aims to uncover the cellular and molecular pathways that help prevent the inheritance of mtDNA mutations to offspring by employing cutting-edge genetic technologies that the laboratory has recently developed in the germline of an animal model system. This Project will generate new knowledge in the area of mitochondrial genetics and evolution. Expected outcomes include the development of new theories for mtDNA inheritance, which should provide significant benefits for agricultural breeding programs and the interpretation of mtDNA inheritance patterns in the human population.Read moreRead less