The nature of self-recognition: novel approaches to vexing questions. Mirror self-recognition has often been interpreted as evidence for the presence of some form of self-concept/awareness. Children from age 2 onwards investigate their own bodies after seeing a novel mark on their heads in the mirror (surreptitiously placed in their hair by the experimenter). Younger children and most animals do not respond to their images in such a way (instead, for example, treating it as another individual). ....The nature of self-recognition: novel approaches to vexing questions. Mirror self-recognition has often been interpreted as evidence for the presence of some form of self-concept/awareness. Children from age 2 onwards investigate their own bodies after seeing a novel mark on their heads in the mirror (surreptitiously placed in their hair by the experimenter). Younger children and most animals do not respond to their images in such a way (instead, for example, treating it as another individual). The present experiments probe the nature of self-recognition using novel digital video technology rather than mirrors. This technology allows us to manipulate the contingency and appearance of the image. Five studies investigate the performance of 2 to 4-year-old children, autistic children, chimpanzees and dolphins to determine whether they recognize themselves and what underwrites their performance on the tasks. The innovative use of modern technology is expected to answer some of the most persistent questions in psychology.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowle ....Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowledge base of how the nervous system develops or degenerates, but the results will provide crucial information for future studies based on genetic approaches, drug therapies and bioengineering technology to repair the injured nervous system.Read moreRead less
Thinking about the future: The nature and development of mental time travel. This project is one of the first systematic investigations into the development of the human capacity to consider future events. A variety of novel tasks will probe what children know about the future and how it relates to their ability to reason about past events. Comparisons between children and apes will further inform us about the nature of this crucial mental skill. The findings will provide valuable information fo ....Thinking about the future: The nature and development of mental time travel. This project is one of the first systematic investigations into the development of the human capacity to consider future events. A variety of novel tasks will probe what children know about the future and how it relates to their ability to reason about past events. Comparisons between children and apes will further inform us about the nature of this crucial mental skill. The findings will provide valuable information for developing appropriate educational approaches and for our understanding of abnormalities. As international leaders in this field, we are in an ideal position to conduct this research, offer unique opportunities for postgraduate training, and to continue in Australia's outstanding tradition of excellence in basic research.Read moreRead less
Evolution of Mind: The representational capacities of gibbons (H. syndactylus) and the common ancestor of humans and apes. This research is the first systematic investigation into the mental capacity of gibbons. These apes are one of our closest genetic relatives. Results of the research will inform human-animal comparisons and investigations into the evolution of the human mind. More appropriate enrichment measures for captive apes could be developed as a result. It is hoped that this work will ....Evolution of Mind: The representational capacities of gibbons (H. syndactylus) and the common ancestor of humans and apes. This research is the first systematic investigation into the mental capacity of gibbons. These apes are one of our closest genetic relatives. Results of the research will inform human-animal comparisons and investigations into the evolution of the human mind. More appropriate enrichment measures for captive apes could be developed as a result. It is hoped that this work will also lead to new collaborations with Indonesia, home of many gibbon species. The proposed research continues Australia's outstanding tradition of excellence in basic research. Read moreRead less
A shared genetic basis for development of the nervous system and glands. Fruit flies possess strikingly similar versions of the genes that promote normal human development. The list of systems with genetic parallels between humans and fruit flies includes the respiratory and circulatory systems; cardiovascular development and disease; sleep; learning and memory; brain development and disease; taste, sight, smell and hearing. This project could add at least some human glands, the mucous-secreting ....A shared genetic basis for development of the nervous system and glands. Fruit flies possess strikingly similar versions of the genes that promote normal human development. The list of systems with genetic parallels between humans and fruit flies includes the respiratory and circulatory systems; cardiovascular development and disease; sleep; learning and memory; brain development and disease; taste, sight, smell and hearing. This project could add at least some human glands, the mucous-secreting goblet cells, to this list, providing a potentially useful model for studying human diseases associated with gland dysfunction. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668450
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Upgrade of comparative phenotypical and functional cell analysis at James Cook University. North Queensland is a fast growing region with significant need for the development of a world-class research facility. James Cook University has recently established the Comparative Genomics Centre at the School of Pharmacy and Molecular Sciences, which will contribute to education and basic research in the region. The research outcomes from the projects of the Comparative Genomics Centre and affiliated l ....Upgrade of comparative phenotypical and functional cell analysis at James Cook University. North Queensland is a fast growing region with significant need for the development of a world-class research facility. James Cook University has recently established the Comparative Genomics Centre at the School of Pharmacy and Molecular Sciences, which will contribute to education and basic research in the region. The research outcomes from the projects of the Comparative Genomics Centre and affiliated laboratories facilitated by the analytical flow cytometer will support the definition and identification of the interactions between genetic and environmental factors in disease and will help to attract researchers. Results from this work will aid the search for therapies for specific health problems.Read moreRead less
Bioinformatics network for the interrogation of adult stem cells. This project addresses the National Research Priority 'Frontier Technologies for Building and Transforming Australian Industries'. The use of state of the art DNA sequencing results in huge amounts of data that is hard to interpret without the use of computers. This project builds Australia's capacity to deal with huge biological datasets by creating software and expertise in handling these datasets. The application of this softwa ....Bioinformatics network for the interrogation of adult stem cells. This project addresses the National Research Priority 'Frontier Technologies for Building and Transforming Australian Industries'. The use of state of the art DNA sequencing results in huge amounts of data that is hard to interpret without the use of computers. This project builds Australia's capacity to deal with huge biological datasets by creating software and expertise in handling these datasets. The application of this software and expertise to our stem cell population in Parkinson's disease patients will enable new insight into the difference between patients and controls.Read moreRead less
Specialized glial cells within the hippocampus of the brain regulate important morphological events in embryonic development. Memories of past experiences, and our ability to learn new information, is processed in a region of the brain called the hippocampus. In order for this to occur, the cells that make up the hippocampus must form correctly during embryonic development. This proposal investigates the cellular and molecular mechanisms regulating hippocampal formation. The national benefit of ....Specialized glial cells within the hippocampus of the brain regulate important morphological events in embryonic development. Memories of past experiences, and our ability to learn new information, is processed in a region of the brain called the hippocampus. In order for this to occur, the cells that make up the hippocampus must form correctly during embryonic development. This proposal investigates the cellular and molecular mechanisms regulating hippocampal formation. The national benefit of this work is to provide basic knowledge about the processes that underlie correct brain formation and function, and to understand what processes are disrupted when the brain fails to function correctly. Such disruptions lead to mental retardation and learning difficulties, and in the aged, an inability to form and store new memories, as occurs in dementia.Read moreRead less
Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The pr ....Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The project investigates this signal mechanism. The results will advance understanding of the mechanisms regulating development and in particular link the mother's nutritive status to her fertility during very early pregnancy.Read moreRead less