Sex determination in dragons: Genetics, epigenetics and environment. This project aims to discover the master sex-determining gene in a reptile, how that gene is differentially regulated in males and females and by temperature, and to identify evolutionary drivers of transitions between genetic and environmental sex determination. In many reptiles, like mammals, chromosomes determine sex. In others, the temperature at which their eggs are incubated determines sex. This project will study how tem ....Sex determination in dragons: Genetics, epigenetics and environment. This project aims to discover the master sex-determining gene in a reptile, how that gene is differentially regulated in males and females and by temperature, and to identify evolutionary drivers of transitions between genetic and environmental sex determination. In many reptiles, like mammals, chromosomes determine sex. In others, the temperature at which their eggs are incubated determines sex. This project will study how temperature reverses chromosomal sex determination in dragon lizards. This could show how climatic extremes affect the biology of climate sensitive reptiles, and understand their vulnerability to climate change.Read moreRead less
The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
The evolution and conservation consequences of promiscuity in plants pollinated by vertebrates. Pollen dispersal between plants, predominantly by insects and wind, is characteristically restricted to nearest neighbours. Recent molecular analysis of paternity for a Banksia pollinated by nectar-feeding birds showed atypical pollen dispersal, with high multiple paternity, wide outcrossing and local panmixis. With much of the Australian flora also bird-pollinated, our initial results have potentiall ....The evolution and conservation consequences of promiscuity in plants pollinated by vertebrates. Pollen dispersal between plants, predominantly by insects and wind, is characteristically restricted to nearest neighbours. Recent molecular analysis of paternity for a Banksia pollinated by nectar-feeding birds showed atypical pollen dispersal, with high multiple paternity, wide outcrossing and local panmixis. With much of the Australian flora also bird-pollinated, our initial results have potentially wide and novel significance. This project proposes to test the generality of our observations for other vertebrate-pollinated species, and to test the conservation and evolutionary consequences of reduced pollen dispersal caused by habitat fragmentation and declining pollinators for a pollination paradigm facilitating promiscuity.Read moreRead less
Social, economic and health vulnerabilities in Indonesia. This project aims to study and provide ways to overcome vulnerability in Indonesia. Half the Indonesian population is still clustered around the poverty line, contributing to their vulnerability. This project will identify vulnerable groups and why they are vulnerable. Using a common framework of the life course in eight Indonesian field sites, this project will investigate whether social networks and welfare programs reduce vulnerability ....Social, economic and health vulnerabilities in Indonesia. This project aims to study and provide ways to overcome vulnerability in Indonesia. Half the Indonesian population is still clustered around the poverty line, contributing to their vulnerability. This project will identify vulnerable groups and why they are vulnerable. Using a common framework of the life course in eight Indonesian field sites, this project will investigate whether social networks and welfare programs reduce vulnerability, and pinpoint strategies for reducing vulnerabilities in the future. The project expects to show how vulnerable citizens in Indonesia can be made more secure, helping to build a more stable and prosperous region.Read moreRead less
Sustaining India's economic transformation: challenges, prospects and implications for Australia and the Pacific region. India's emergence from economic stagnation is beginning to have a profound impact on the world economy, including Australia. This project aims to investigate the sources of India's growth and the reforms needed to ensure that growth generates reductions in poverty and ensures equity and political stability.
Economic Growth and Real Exchange Rates. Exchange rate movements are important elements of Australia's economic environment. Protectionist interests in the US and Europe, constrained by WTO trade rules, accuse East Asian economies of deliberate undervaluation. While exchange rate movements are not readily predictable in the short run, long run changes in underlying real exchange rates are amenable to economic analysis using structural models. The clearer understanding of these forces, toward ....Economic Growth and Real Exchange Rates. Exchange rate movements are important elements of Australia's economic environment. Protectionist interests in the US and Europe, constrained by WTO trade rules, accuse East Asian economies of deliberate undervaluation. While exchange rate movements are not readily predictable in the short run, long run changes in underlying real exchange rates are amenable to economic analysis using structural models. The clearer understanding of these forces, toward which this project is directed, will better guide investment in the region, including in Australia, and more importantly, it will better inform future policy debates surrounding currency movements.Read moreRead less
Advancing future primary teachers' engagement in science inquiry learning. Australia's challenges in regard to scientific literacy and growth of student enrolments in science need to be addressed at multiple levels, starting with the preparation of future primary teachers. Promoting children's early interest in inquiry-based science is essential, yet a challenge for many teachers. This project examines the complex and dynamic interplay of cognitive, metacognitive and emotional processes in futur ....Advancing future primary teachers' engagement in science inquiry learning. Australia's challenges in regard to scientific literacy and growth of student enrolments in science need to be addressed at multiple levels, starting with the preparation of future primary teachers. Promoting children's early interest in inquiry-based science is essential, yet a challenge for many teachers. This project examines the complex and dynamic interplay of cognitive, metacognitive and emotional processes in future primary teachers' engagement in collaborative inquiry-based science activities. A comprehensive intervention based on these insights aims to determine how scaffolding productive engagement can improve the quality of primary teachers' preparation for inquiry-based science.Read moreRead less
Reciprocal Accountability and Public Value in Aboriginal Organisations. This project aims to examine the different meanings of ‘public value’ and accountability in the work of Aboriginal organisations. Aboriginal organisations in the Kimberley region are funded by governments to deliver services that are of value to the public. They also reflect Aboriginal culture and identity, and represent Aboriginal interests. This also creates value for their own publics. This project investigates the tensio ....Reciprocal Accountability and Public Value in Aboriginal Organisations. This project aims to examine the different meanings of ‘public value’ and accountability in the work of Aboriginal organisations. Aboriginal organisations in the Kimberley region are funded by governments to deliver services that are of value to the public. They also reflect Aboriginal culture and identity, and represent Aboriginal interests. This also creates value for their own publics. This project investigates the tension between these two ways of understanding public value. It investigates accountability for public value creation, whether it reflects the real value of Aboriginal organisations, and whether it can be done better. The project plans to draw on anthropology and public administration theory.Read moreRead less
Navigating tipping points in complex dynamical systems. This project aims to use applied mathematics to investigate the onset of tipping points in dynamical systems. Working with clinicians and practicing engineers, the project aims to contribute to the development of new treatment regimes for dynamical diseases and develop improved management strategies for resource focussed engineering industries. This should provide significant benefit to many areas, including the personalised treatment of di ....Navigating tipping points in complex dynamical systems. This project aims to use applied mathematics to investigate the onset of tipping points in dynamical systems. Working with clinicians and practicing engineers, the project aims to contribute to the development of new treatment regimes for dynamical diseases and develop improved management strategies for resource focussed engineering industries. This should provide significant benefit to many areas, including the personalised treatment of disease.Read moreRead less
Multi-object Estimation for Live-Cell Microscopy. The objective of this project is to develop new tools for the inference of biological information from live-cell data to facilitate analysis of experiments and speed up discovery in cell biology. The new tools would provide reliable, consistent inference requiring no manual intervention and able to process large volumes of data in a timely manner. This would equip biologists with a vehicle that could move them closer to the goal of understanding ....Multi-object Estimation for Live-Cell Microscopy. The objective of this project is to develop new tools for the inference of biological information from live-cell data to facilitate analysis of experiments and speed up discovery in cell biology. The new tools would provide reliable, consistent inference requiring no manual intervention and able to process large volumes of data in a timely manner. This would equip biologists with a vehicle that could move them closer to the goal of understanding the mechanism behind biological processes.Read moreRead less