Smart Information Use for PET-CT Quantitative Molecular Imaging. This project aims to use advanced computing algorithms to tackle
challenging problems associated with a new medical technology called
PET-CT which combines two imaging modalities in one device. While this technology is very new and has great potential in cancer and brain disorders, it also poses major challenges for information processing and transmission. We will address these challenges by developing advanced algorithms that op ....Smart Information Use for PET-CT Quantitative Molecular Imaging. This project aims to use advanced computing algorithms to tackle
challenging problems associated with a new medical technology called
PET-CT which combines two imaging modalities in one device. While this technology is very new and has great potential in cancer and brain disorders, it also poses major challenges for information processing and transmission. We will address these challenges by developing advanced algorithms that optimally extract information from PET and CT using mathematical models that correct for the various sources of inaccuracy. Our research will put Australian biomedical researchers and healthcare professionals at the forefront of advanced medical imaging technology.Read moreRead less
An Innovative Multimedia Framework for Multidimensional PET-CT Image Navigation and Communication. The recent development of a combined positron emission tomography and computerized tomography (PET-CT) device ushers in a completely new era in molecular imaging that will revolutionize the approach to imaging in the clinical environment. In this project, we address a number of the critical challenges associated with the introduction of PET-CT, and provide a range of innovative multimedia technolo ....An Innovative Multimedia Framework for Multidimensional PET-CT Image Navigation and Communication. The recent development of a combined positron emission tomography and computerized tomography (PET-CT) device ushers in a completely new era in molecular imaging that will revolutionize the approach to imaging in the clinical environment. In this project, we address a number of the critical challenges associated with the introduction of PET-CT, and provide a range of innovative multimedia technologies to visualize, manipulate and deliver these multi-dimensional data. Our research will greatly enhance the clinical and research benefits of PET-CT and facilitate new discoveries which will have a significant scientific and social impact in Australia and the world at large.Read moreRead less
Automated 3-Dimensional Biomedical Registration for Whole-body Images from Combined PET/CT Scanners. This project will aid rapid assimilation of very large medical imaging datasets from different imaging devices, and will have clinical applications in diagnosis and treatment and improve patient care. The research, when extended to protein registration, will facilitate analysis of DNA and advance research in bioinformatics and biotechnology. The research could also be used for target recognition, ....Automated 3-Dimensional Biomedical Registration for Whole-body Images from Combined PET/CT Scanners. This project will aid rapid assimilation of very large medical imaging datasets from different imaging devices, and will have clinical applications in diagnosis and treatment and improve patient care. The research, when extended to protein registration, will facilitate analysis of DNA and advance research in bioinformatics and biotechnology. The research could also be used for target recognition, mosaic construction, content-based retrieval, in remote sensing and multimedia. Benefits to Australia include the provision of a readily adaptable image registration program for patient care (e.g., early detection of cancers, dementia), cutting-edge research, high-quality training for students, and encouraging international research collaboration.Read moreRead less
A new generation of multi-modality biomedical image visualisations. This research will overcome the urgent and significant burden in the routine clinical visualisation of multiple-modality biomedical image data, which are complex and exquisitely detailed from the new generation of high-resolution medical imaging scanners. Together with our industry partner RPA Hospital, we will produce 3D visualisation methodologies that will simplify and revolutionise the way biomedical data are visualised, ana ....A new generation of multi-modality biomedical image visualisations. This research will overcome the urgent and significant burden in the routine clinical visualisation of multiple-modality biomedical image data, which are complex and exquisitely detailed from the new generation of high-resolution medical imaging scanners. Together with our industry partner RPA Hospital, we will produce 3D visualisation methodologies that will simplify and revolutionise the way biomedical data are visualised, analysed and interpreted by imaging specialists and disseminated to doctors and patients. Given the pivotal role that imaging plays in modern healthcare, this will improve diagnosis and assessment, and enhance Australia's leading position in the development of frontier technologies.Read moreRead less
Large scale knowledge and image based biomedical modelling and derivation of PET-CT disease maps and treatment response. The smart use of information to improve, promote and maintain good healthcare is a critical mission for our country. Cancer is a serious problem in Australian society and 1 in 4 individuals will be affected by it in their lifetime. Our research is focussed on two types of cancer - lung cancer and the lymphomas - and it will use IT in a novel way to extract important informatio ....Large scale knowledge and image based biomedical modelling and derivation of PET-CT disease maps and treatment response. The smart use of information to improve, promote and maintain good healthcare is a critical mission for our country. Cancer is a serious problem in Australian society and 1 in 4 individuals will be affected by it in their lifetime. Our research is focussed on two types of cancer - lung cancer and the lymphomas - and it will use IT in a novel way to extract important information from a very large biomedical data repository. We hope that it will improve personalised diagnosis and treatment in these cancers and provide new information on how some cancers spread and resist our usual treatments. We think our techniques will contribute to other research areas such as astronomy, agriculture, water/energy resources, and security.Read moreRead less
Information Technology Aided Diagnosis of Dementia with PET-CT Imaging. Dementia is a significant health problem and approximately 162,000 Australians currently suffer from this disease, with costs estimated at $6 billion annually in Australia and a profound effect on the lives of carers and family members. With the ageing of the Australian population, the patient number is expected to rise to 500,000 by 2040.This research will apply innovative IT approaches to develop computer assisted diagnosi ....Information Technology Aided Diagnosis of Dementia with PET-CT Imaging. Dementia is a significant health problem and approximately 162,000 Australians currently suffer from this disease, with costs estimated at $6 billion annually in Australia and a profound effect on the lives of carers and family members. With the ageing of the Australian population, the patient number is expected to rise to 500,000 by 2040.This research will apply innovative IT approaches to develop computer assisted diagnosis of early dementia, when treatment is possible, from combined functional and anatomical imaging modalities (PET-CT). This will not only add considerable value to Australia's medical imaging infrastructure and smart use of information, but will ultimately also deliver substantial benefits to our nation and community.Read moreRead less
Integrated multi-level interpretation and its applications for intelligent multimodality biomedical image navigation, retrieval and tracking. The 64- and 128-slice positron emission tomography – computed tomography (PET-CT) devices at the Royal Prince Alfred Hospital were the first in the country. These scanners, with the medical cyclotron and radiochemistry facilities, represent an investment of over A$13 million. This project will address pressing issues in optimising the utilisation of the in ....Integrated multi-level interpretation and its applications for intelligent multimodality biomedical image navigation, retrieval and tracking. The 64- and 128-slice positron emission tomography – computed tomography (PET-CT) devices at the Royal Prince Alfred Hospital were the first in the country. These scanners, with the medical cyclotron and radiochemistry facilities, represent an investment of over A$13 million. This project will address pressing issues in optimising the utilisation of the information and systems to provide better service to patients and referring clinicians. This research will add considerable value to Australia's medical imaging infrastructure and healthcare delivery; and advance scientific research in better understanding of system biology, physiology and pathology. The research outcomes will strengthen Australia’s leading position in biomedical information technology research and Australian medical imaging expertise.Read moreRead less
Trust and Safety in Autonomous Mobility Systems: A Human-centred Approach. This project aims to understand the link between trust, safety, and the public acceptance of driverless cars. The uptake of autonomous mobility systems relies upon public trust. Recent injuries, and even a fatality, have highlighted the risks they pose to pedestrians in particular. The project investigates new interfaces for improving public trust and pedestrial safety by allowing vehicles to communicate with the people a ....Trust and Safety in Autonomous Mobility Systems: A Human-centred Approach. This project aims to understand the link between trust, safety, and the public acceptance of driverless cars. The uptake of autonomous mobility systems relies upon public trust. Recent injuries, and even a fatality, have highlighted the risks they pose to pedestrians in particular. The project investigates new interfaces for improving public trust and pedestrial safety by allowing vehicles to communicate with the people around them. Along the way, it develops a validated approach for simulating real interactions with autonomous vehicles in a virtual-reality environment. Benefits include strategies for making driverless cars safer for pedestrians and a new approach for testing solutions to this emerging problem in a low-cost, low-risk way.Read moreRead less
A Gesture-Based Interface for Designing in Virtual Reality. Many design professions including architecture, fashion, and engineering can benefit from the outcomes of this project and may return financial benefits to Australia, since they heavily rely on sketching in the conceptual design process. Other areas, such as films, computer games, user interface design that involves storyboarding and visualization may also benefit from sketching in virtual reality. Further research may be carried out us ....A Gesture-Based Interface for Designing in Virtual Reality. Many design professions including architecture, fashion, and engineering can benefit from the outcomes of this project and may return financial benefits to Australia, since they heavily rely on sketching in the conceptual design process. Other areas, such as films, computer games, user interface design that involves storyboarding and visualization may also benefit from sketching in virtual reality. Further research may be carried out using a variety of VR facilities and a responsive workbench (3D interactive table-top display) to allow distributed Virtual Prototyping between geographically separated design teams, to assemble the product drawn using a force feedback device to place Australia in a leading position.Read moreRead less
Cognitive Features of Decision Support System Interfaces. The complex and time-constrained nature of the contemporary workplace is such that there is an increasing dependence on technology to assist operators in formulating accurate and timely decisions. This project is designed to ensure that the process through which this information is presented to operators is as efficient and effective as possible under the circumstances. Using an innovative approach to the development of such decision supp ....Cognitive Features of Decision Support System Interfaces. The complex and time-constrained nature of the contemporary workplace is such that there is an increasing dependence on technology to assist operators in formulating accurate and timely decisions. This project is designed to ensure that the process through which this information is presented to operators is as efficient and effective as possible under the circumstances. Using an innovative approach to the development of such decision support systems, the outcomes of this project will direct the development of this type of technology in the future and, ultimately, lead to more effective and more efficient decision-making under uncertainty.Read moreRead less