Quantification of the Remineralisation of Enamel. This project has three specific aims:
1. To quantify the ultrastructure and mechanisms of remineralisation of enamel using scanning and transmission electron microscopy.
2. To determine the mechanical properties of remineralised tissue and compare with those of sound enamel.
3. To develop an in-vivo optical fibre probe for monitoring and quantifying the changes of mineralised carious tissue during remineralisation.
This project will enable ....Quantification of the Remineralisation of Enamel. This project has three specific aims:
1. To quantify the ultrastructure and mechanisms of remineralisation of enamel using scanning and transmission electron microscopy.
2. To determine the mechanical properties of remineralised tissue and compare with those of sound enamel.
3. To develop an in-vivo optical fibre probe for monitoring and quantifying the changes of mineralised carious tissue during remineralisation.
This project will enable patients prone to orthodontic induced root resorption to be identified and also to assist with validating repair of enamel tooth structure in a non-surgical manner. It is anticipated to result in the development of a novel fibre optic instrument with applications beyond dentistry.
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A Longitudinal Controlled Study To Prevent Early Childhood Caries From Ages 0-6 Years In A Disadvantaged Community In Queensland
Funder
National Health and Medical Research Council
Funding Amount
$695,788.00
Summary
Rampant dental decay in young children is very difficult to prevent. The study will follow a group of high risk children from birth to 6 years of age to test the effectiveness of antibacterial and remineralising agents to prevent dental decay. Our early results showed that these agents have good potential for removing decay-causing bacteria and preventing dental cavities. We expect our long term results will yield valuable information for dental prevention for young children worldwide.
Minimally Invasive Approach To Manage Early Childhood Caries In Aboriginal Preschoolers
Funder
National Health and Medical Research Council
Funding Amount
$1,488,220.00
Summary
The treatment of dental decay in young children is often undertaken in a hospital, which is costly and risky. A treatment approach tested among a non-Aboriginal preschool population in WA, using hand instruments only and without the use of local anaesthesia, showed nearly a ten-fold reduction in the need for specialist dental care. This study will test the effectiveness of dental treatment of preschool children in rural and remote Aboriginal communities, using the alternative approach.
Sealing Ability Of Adhesive Restorations In Caries And Non-caries Affected Teeth.
Funder
National Health and Medical Research Council
Funding Amount
$46,081.00
Summary
Dental fillings are used in treating tooth decay. Tooth coloured materials have become more common than metal fillings. A factor in determining the effectiveness of these adhesive restorations is analysing the bond strength between the filling and tooth. A poor bond between the restorative material and tooth is likely to produce problems such as tooth sensitivity and recurrent decay. We intend to investigate the sealing ability of adhesive restorations to carious affected teeth and sound teeth.
Methods To Improve Detail Reproduction Of Elastic Impression Materials
Funder
National Health and Medical Research Council
Funding Amount
$96,656.00
Summary
If a dental prosthesis is to fit precisely in the mouth, an accurate impression must be taken of the teeth and surrounding tissues. This research aims to evaluate variable surface conditions which may be taken into consideration to achieve an accurate impression, such as moisture, temperature, and the presence of contaminants. Although any distortions as a result of material interactions would be limited to the surface interface, inaccuracies here may ultimately compromise treatment success.
Does Teriparatide Reverse Osteonecrosis Of The Jaw In Patients With Cancer? A Randomised, Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$357,412.00
Summary
Osteonecrosis of the jaw (ONJ) is debilitating and associated with drugs that increase bone strength and reduce the bone remodeling rate (bisphosphonates or denosumab). Up to 15% of patients with bone marrow cancer and 1 out of 952 patients with osteoporosis treated with bisphosphonates may get ONJ. This 8-week trial of subcutaneous teriparatide (a hormone that forms new bone) or placebo injections aims to promote resolution of ONJ, measured clinically and by x-ray, and improve quality of life.
Advancing Aboriginal Australian Oral Health Through Intervention Studies, Longitudinal Studies, Modelling And Surveillance
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Indigenous Australians experience worse oral health than their non-Indigenous counterparts. This Fellowship aims to advance Aboriginal Australian oral health through intervention studies, longitudinal studies, modelling & surveillance. The fellowship will capitalise on past collaborations with local, national and international researchers of repute, and seek to forge new partnerships that will be of benefit to Indigenous oral health at a global level.
The CCRE for Oral Health will focus on the prevention and treatment of oral diseases and disorders and their clinical consequences. Research will emphasise three areas of clinical care that are critical to the management of oral health, systemic health and general well-being: 1.Primary prevention to prevent disease onset 2. Diagnosis and risk prediction for oral conditions 3. Clinical intervention
ONLINE HEALTH CARE SYSTEM TO PROVIDE SPECIALIST CARE TO RURAL, REMOTE AND UNDESERVED REGIONS
Funder
National Health and Medical Research Council
Funding Amount
$360,475.00
Summary
Our aim is to develop and validate an online health care system to link remote and rural health professionals, facilities and patients into an online community. The proposed online system will provide medical advice and diagnosis, consumer health care information services, support groups, information and distance education for those working in the health care as well as the community and assistance in the operational and medical decision-making process. Less expensive health care personnel shoul ....Our aim is to develop and validate an online health care system to link remote and rural health professionals, facilities and patients into an online community. The proposed online system will provide medical advice and diagnosis, consumer health care information services, support groups, information and distance education for those working in the health care as well as the community and assistance in the operational and medical decision-making process. Less expensive health care personnel should be able to use the system with little training in remote and rural areas. This project will generate knowledge about the practicality of low cost but highly effective e-health system. It will be easier to disseminate health care information and health evaluation processes to patients, doctors, nurses and other health care workers. It will also be possible to obtain information about image resolution, suitable compression algorithms and compression levels for different diseases pathologies.Read moreRead less