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A Controlled Multi-faceted Community Intervention Trial To Improve The Oral Health Of Preschool Aged Child In Rural VIC
Funder
National Health and Medical Research Council
Funding Amount
$100,000.00
Summary
Pre-school aged children living in rural Victoria have worse dental health than that of their metropolitan counterparts. This is due in part to the lack of exposure to water fluoridation, difficulty accessing dental services and other sociodemographic issues. Whilst most pre-school aged children do not routinely get taken to a dentist, they do come into contact with local community nursing and medical staff. The aim of this project is to evaluate the feasibility and effectiveness of improving or ....Pre-school aged children living in rural Victoria have worse dental health than that of their metropolitan counterparts. This is due in part to the lack of exposure to water fluoridation, difficulty accessing dental services and other sociodemographic issues. Whilst most pre-school aged children do not routinely get taken to a dentist, they do come into contact with local community nursing and medical staff. The aim of this project is to evaluate the feasibility and effectiveness of improving oral health for these preschool aged children by developing oral health promotion skills in the existing local medical, nursing and dental practitioners, augmented by referral pathways that improve accessibility to dental services.Read moreRead less
Comparison Of Three Workforce Models To Improve Oral Health & Public Dental Care For Disadvantaged Adults Living In Rura
Funder
National Health and Medical Research Council
Funding Amount
$98,131.00
Summary
The proposed study will compare two workforce models incorporating new clinical teams with new programs (oral health promotion, prevention and timely restorative dental care) in targeted communities in rural Tasmania with the existing model of public sector dental service. The results will provide an evidence-base for both workforce and service delivery policy and planning to improve access and equity in oral health and public dental care for people in rural areas.
Dental Care And Oral Health For The Indigenous Communities Of South Australia's Mid-north
Funder
National Health and Medical Research Council
Funding Amount
$100,000.00
Summary
Improving access to dental services and oral health for Indigenous communities is a high priority. This project will initially involve the evaluation of oral health programs for Indigenous children in Port Augusta. This will guide the planning and implementation of programs for the other age groups and for the remote communities serviced by Pika Wiya Health Service. In addition, the project group will investigate the appropriateness of the developed strategies for implementation in other communi ....Improving access to dental services and oral health for Indigenous communities is a high priority. This project will initially involve the evaluation of oral health programs for Indigenous children in Port Augusta. This will guide the planning and implementation of programs for the other age groups and for the remote communities serviced by Pika Wiya Health Service. In addition, the project group will investigate the appropriateness of the developed strategies for implementation in other communities.Read moreRead less
Remote Indigenous Oral Health Testing A Commmunity Based Model Of Oral Health Promotion
Funder
National Health and Medical Research Council
Funding Amount
$77,152.00
Summary
Development and trial of an oral health promotion package for remote Aboriginal groups based on community consultations. This would include the development of visual health promotion packages in local language. The aim is to develop sustainable change in oral health behaviours.
Intervention Strategies For The Prevention Of Early Childhood Caries
Funder
National Health and Medical Research Council
Funding Amount
$125,000.00
Summary
Rampant dental decay in young children remains an important challenge for preventive dentistry. Although it is a preventable disease, the prevalence is high in many disadvantaged communities. The study will examine a few intervention programs to determine their effectiveness in preventing early childhood decay. These include brushing the teeth with a safe, dental antibacterial gel compared to traditional oral hygiene methods. Brushing with antibacterial gels at crucial times during the establish ....Rampant dental decay in young children remains an important challenge for preventive dentistry. Although it is a preventable disease, the prevalence is high in many disadvantaged communities. The study will examine a few intervention programs to determine their effectiveness in preventing early childhood decay. These include brushing the teeth with a safe, dental antibacterial gel compared to traditional oral hygiene methods. Brushing with antibacterial gels at crucial times during the establishment of the oral flora is likely to prevent decay-causing bacteria from colonising a child’s mouth, so that the risk of dental decay is reduced, not only during childhood, but possibly extending to adulthood as well.Read moreRead less
Early Intervention To Prevent Childhood Obesity Among A Disadvantaged Population: A Home-based Randomised Controlled Tri
Funder
National Health and Medical Research Council
Funding Amount
$675,082.00
Summary
This intervention research will conduct a randomised controlled trial, of a community-based early childhood home visiting intervention designed to improve family and behavioural risk factors for childhood obesity and overweight. This intervention which will be developed in collaboration with the Health Promotion Unit, Child and Family Health Nurses, university academic experts and mothers in the community promises to deliver significant health and social benefits, in particular, preventing early ....This intervention research will conduct a randomised controlled trial, of a community-based early childhood home visiting intervention designed to improve family and behavioural risk factors for childhood obesity and overweight. This intervention which will be developed in collaboration with the Health Promotion Unit, Child and Family Health Nurses, university academic experts and mothers in the community promises to deliver significant health and social benefits, in particular, preventing early onset of childhood obesity. It will result in a series of recommendations for policies and practical methods for promoting healthy feeding and physical activity of infants under two years of age with particular application to families who are socially and economically disadvantaged. These policies and practical methods for preventing childhood obesity could be used across Australia.Read moreRead less
Chimeric Virus-like Particles (VLPs) Displaying H1, H3 And H5 Haemagglutinins - Construction And Immunogenicity
Funder
National Health and Medical Research Council
Funding Amount
$207,543.00
Summary
Virus-like particles (VLPs) provoke strong immune responses in the body. We have developed a novel VLP system that allows the production of VLPs containing foreign vaccine antigens of much larger size than previously possible, and have shown that these VLPs provoke strong immune responses in mice without the use of adjuvants. The capacity of these VLPs is large enough to accommodate the most important vaccine antigen of influenza, the haemagglutinin (HA) molecule. We will test whether VLPs can b ....Virus-like particles (VLPs) provoke strong immune responses in the body. We have developed a novel VLP system that allows the production of VLPs containing foreign vaccine antigens of much larger size than previously possible, and have shown that these VLPs provoke strong immune responses in mice without the use of adjuvants. The capacity of these VLPs is large enough to accommodate the most important vaccine antigen of influenza, the haemagglutinin (HA) molecule. We will test whether VLPs can be produced containing each of the three most important HA types _ H1 and H3 that are currently circulating in man, and H5 (avian) that is considered a pandemic threat. VLPs will be tested for their ability to induce neutralizing antibody and cellular immune responses in mice, and for their ability to protect ferrets from influenza infection. If successful, the HA-VLP system would provide a method for the rapid production of new influenza vaccines using large-scale fermentation technology as for hepatitis B and many other vaccines, rather than eggs or cell culture as used for current influenza vaccines.Read moreRead less
Assessment Of Alpha-galactosylceramide As A Novel Adjuvant For Pandemic Influenza: A Virua Vaccine
Funder
National Health and Medical Research Council
Funding Amount
$220,042.00
Summary
The occurrence of human infections with pathogenic avian H5N1 Influenza A viruses was the first documentation of these viruses demonstrating an ability to directly transmit from birds to humans. The virulent nature of these infections, and the fact that there is no pre-existing immunity to these viruses in the human population has raised the concern that these viruses may emerge to cause the next influenza pandemic. Vaccination is our most effective way of protecting against influenza infection, ....The occurrence of human infections with pathogenic avian H5N1 Influenza A viruses was the first documentation of these viruses demonstrating an ability to directly transmit from birds to humans. The virulent nature of these infections, and the fact that there is no pre-existing immunity to these viruses in the human population has raised the concern that these viruses may emerge to cause the next influenza pandemic. Vaccination is our most effective way of protecting against influenza infection, however there are no commercially available avian influenza vaccines available. Moreover, recent evidence suggests current vaccines strategies may be less than effective. This proposal aims to evaluate the efficacy of a novel vaccine strategy that promotes immune protection against a potential pandemic influenza strain.Read moreRead less