Modelling The Impact Of Global Climate Change On The Epidemiology Of Infectious Diseases In Bangladesh
Funder
National Health and Medical Research Council
Funding Amount
$118,988.00
Summary
Climate change may impact on human health via a change in the distribution and pathogenicity of infectious diseases, particularly in the South Asian region. This study will use high quality environmental and clinical data from an established time-series collated in Bangladesh, to better inform mathematical models which may predict future changes in infectious diseases epidemiology. Accurate and valid modelling can be valuable in guiding future public health policy for vulnerable populations.
Early Diagnosis And Prognosis Of Severe Dengue In Vietnamese Children
Funder
National Health and Medical Research Council
Funding Amount
$689,323.00
Summary
Dengue is a mosquito-borne viral infection. Tropical Australia has experienced multiple outbreaks of dengue in the last decade. This project, conducted in Ho Chi Minh City, Viet Nam, will define the accuracy of a rapid diagnostic test for the early diagnosis of severe dengue. In doing so, we will also derive an algorithm using simple laboratory and clinical findings that can help identify those patients at greatest risk of severe complications, with benefits for both patients and hospitals.
Immune Correlates Of Early Corticosteroid Therapy In Vietnamese Children And Young Adults With Dengue
Funder
National Health and Medical Research Council
Funding Amount
$467,073.00
Summary
Dengue is a globally important infectious disease. This study will seek to understand how corticosteroids, an immune modulating class of drug, effect the immune responses in children with dengue. The basis for this study is a randomised controlled trial at a large hospital in Viet Nam that treats many patients with dengue. We expect to obtain the laboratory evidence needed to support further clinical trials of this drug and in doing so we will improve our understanding of dengue.
Application Of Mathematical Modelling And Development Of Decision Support Tools For Mosquito-borne Disease
Funder
National Health and Medical Research Council
Funding Amount
$380,558.00
Summary
Mosquito-borne disease affects millions of people in Australia and overseas. Reducing the prevalence of these diseases requires an understanding of their transmission, drug resistance and role of external factors such as climate. This project will use newly developed mathematical and statistical tools to investigate transmission of malaria, and improve the reporting of Ross River and Barmah Forest viruses and dengue. Project outcomes will assist the development of evidence based policy.