Hedgehog Signalling In Limb And Craniofacial Development And Disease
Funder
National Health and Medical Research Council
Funding Amount
$494,544.00
Summary
Anomalies of the face and limbs are amongst the most common features of human birth defects, and their frequent association suggests that the same genes are involved in governing the development of the limbs and face during embryogenesis. We have used a genomics-based approach to identify genes involved in limb development based on their alteration in a mouse model which develops extra fingers and toes. Defects in this mouse result from changes in Gli3, a gene which is known to be important in b ....Anomalies of the face and limbs are amongst the most common features of human birth defects, and their frequent association suggests that the same genes are involved in governing the development of the limbs and face during embryogenesis. We have used a genomics-based approach to identify genes involved in limb development based on their alteration in a mouse model which develops extra fingers and toes. Defects in this mouse result from changes in Gli3, a gene which is known to be important in both limb and face development. Based on the organs in which our genes of interest are active, we believe that they will also play key roles in embryonic development of the limbs, face and other organs. We now plan to investigate the regulation of a subset of these genes based on analysis in mouse models of limb and face development. In addition, we have chosen to further analyse the function of a completely novel gene we have identified which our preliminary studies suggest may play a role in the normal development of the lip and palate. These studies have the potential to shed light on the processes governing how organs develop, as well as on the molecular basis of common birth defects such as polydactyly (extra fingers and toes) and cleft palate.Read moreRead less
Functional Nano-cement Scaffolds For The Treatment Of Osteoporotic Bone Defects
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
Osteoporosis affects 1.2 million Australians and will cost $33.6 billion by 2022. This study aims to develop a novel nano-cement platform for custom-designed bone repair in osteoporosis, by using purpose-designed nanomaterials and advanced 3D printing technique. The research findings will lead to the development of a new bone repair strategy, expand knowledge on both biomaterials engineering and osteoporosis treatment, and improve the quality of life of Australians.
Investigating the effectiveness of teacher education for early career teachers in diverse settings: a longitudinal study. This project investigates the effectiveness of teacher education programs in Victoria and Queensland in preparing teachers for the variety of school settings in which they begin their careers. The findings will inform state and national policy, as well as the work of professional regulation authorities and teacher education providers.
Learning for Teaching in Disadvantaged Schools. This project focuses on what and how primary school teachers learn about improving classroom practices from co-inquiry interventions. The effective diagnosis of student learning difficulties and the design of educational interventions based on such diagnosis is a core component of quality teaching. Yet many teachers have not acquired the knowledge and skills to undertake such learning diagnostic and design work. The project plans to engage practiti ....Learning for Teaching in Disadvantaged Schools. This project focuses on what and how primary school teachers learn about improving classroom practices from co-inquiry interventions. The effective diagnosis of student learning difficulties and the design of educational interventions based on such diagnosis is a core component of quality teaching. Yet many teachers have not acquired the knowledge and skills to undertake such learning diagnostic and design work. The project plans to engage practitioners in co-inquiry through collaborative analysis of professional learning conversations and classroom practices across disadvantaged public schools in urban and regional locations across Queensland. It aims to examine the sustainability of co-inquiry models to improve student learning.Read moreRead less
Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity th ....Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity through access to professional learning and museum and STEM professional community resources is critically important for improving students’ proficiencies, attitudes, and interest in STEM. The project outcome will be to develop a STEM professional learning model that can be used to create a more skilled and educated STEM workforce. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100086
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Teachers' learning in complex times: theorising teacher professional development practices under globalised policy conditions. This project investigates the effects of national standardised testing on the professional development practices of teachers in rural and urban schools in varied Socio-Economic Status communities in Australia. The project will indicate whether and how such testing influences teachers' learning, and subsequent student learning, in these different types of settings.
School-wide approaches for developing social and emotional wellbeing: New understandings of positive identities, emotions and learning in adolescents. School disengagement, suspensions, and emotional problems among adolescents have increased steadily. The Australian Government’s strategic research priority of maximising social and economic participation, therefore, is an urgent need. In partnership with the Queensland Department of Education, Training and Employment, this project aims to test ho ....School-wide approaches for developing social and emotional wellbeing: New understandings of positive identities, emotions and learning in adolescents. School disengagement, suspensions, and emotional problems among adolescents have increased steadily. The Australian Government’s strategic research priority of maximising social and economic participation, therefore, is an urgent need. In partnership with the Queensland Department of Education, Training and Employment, this project aims to test how embedding social and emotional wellbeing into school-wide policies, classroom practices, and self and social strategies of students enhances learning, behavioural, and social outcomes. Implementing whole of school approaches to enhance social participation and wellbeing will build resilient youth and ultimately the social and academic capacity of Australia’s young people.Read moreRead less
Enhancing proportional reasoning, a fundamental but elusive cornerstone of numeracy, through educational technology applications. This project targets numeracy; a national education priority and global measure of education quality. This project will fill an identified research gap about the specific mathematics content to support rich numeracy practices, thus enhancing the professional capacity of teachers of all disciplines to attain this national goal. High numeracy increases work and life cho ....Enhancing proportional reasoning, a fundamental but elusive cornerstone of numeracy, through educational technology applications. This project targets numeracy; a national education priority and global measure of education quality. This project will fill an identified research gap about the specific mathematics content to support rich numeracy practices, thus enhancing the professional capacity of teachers of all disciplines to attain this national goal. High numeracy increases work and life choices, strengthening the social and economic fabric and global competitiveness of Australian society. High numeracy supports access to science, technology, engineering and mathematics; areas in which current enrolments are in decline. This project will define the essence of numeracy for the 21st century, support evidence-based policy decisions and influence classroom practice.Read moreRead less
School retention and second chance schooling. This project is concerned with ensuring that students who experience systemic disadvantage are not excluded from the benefits of a formal education. It provides an account and critique of the growth of second chance schooling options catering to such students in both Australia and the UK.
Responding to Indigenous students' and their communities' voiced experiences regarding effective teaching practices: a catholic education initiative. This project will identify the actions of effective teachers through the voiced comments of Indigenous students and community members and their teachers. Using this information and the literature on culturally located practices, the project will determine the impact of these actions on educational outcomes.