Role Of The Anaphase-Promoting Complex Activator Cdh1 In Oocyte Maturation And Meiotic Aneuploidy
Funder
National Health and Medical Research Council
Funding Amount
$526,878.00
Summary
Eggs containing an incorrect number of chromosomes are described as aneuploid. This project sets out to examine the molecular causes of aneuploidy and why it increases with female age. We focus on the protective role of the protein Cdh1 in this process. The outcome would be to better understand the origins of aneuploidy so as to find methods of decreasing it as women age. This is highly significant given aneuploidy is the leading cause of early embryo loss and produces Down Syndrome babies.
Defining The Molecular Effectors Of Gene/environment Interaction On Mouse Heart Development
Funder
National Health and Medical Research Council
Funding Amount
$749,271.00
Summary
One third of all birth defects involve the heart, and are the most common cause of infant death. Some defects are due to genetic factors, but others arise when the pregnant mother is exposed to environmental stress. We will examine how one stress (low oxygen levels) causes abnormal heart formation in the embryo, look at what causes this at a molecular level, and explore if such stress increases the risk of heart defects in families with a history of such abnormalities
Designing effective learning experiences: Investigating novice and expert teachers’ design processes. Quality teaching leads to quality learning outcomes for students. Primary school teachers are responsible for designing learning experiences for their students in an increasingly complex environment. This project will advance understanding by: characterising and identifying differences in how novice and expert teachers approach the design of learning experiences for their students; capturing exp ....Designing effective learning experiences: Investigating novice and expert teachers’ design processes. Quality teaching leads to quality learning outcomes for students. Primary school teachers are responsible for designing learning experiences for their students in an increasingly complex environment. This project will advance understanding by: characterising and identifying differences in how novice and expert teachers approach the design of learning experiences for their students; capturing expert design processes through practice examples; and investigating how expert practice examples stimulate novice teachers to design learning experiences. This new understanding of teachers' design processes is necessary to enhance teacher preparation and continued professional learning.Read moreRead less
Investigating the effectiveness of teacher education for early career teachers in diverse settings: a longitudinal study. This project investigates the effectiveness of teacher education programs in Victoria and Queensland in preparing teachers for the variety of school settings in which they begin their careers. The findings will inform state and national policy, as well as the work of professional regulation authorities and teacher education providers.
Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity th ....Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity through access to professional learning and museum and STEM professional community resources is critically important for improving students’ proficiencies, attitudes, and interest in STEM. The project outcome will be to develop a STEM professional learning model that can be used to create a more skilled and educated STEM workforce. Read moreRead less
Empowering teachers of middle-years mathematics: becoming self-directed learners. This project will provide innovative strategies to enhance mathematics teaching and learning of middle-years students. It will develop a robust teacher learning development model that can be used by our industry partner and practitioners in the wider educational community to contribute to the development of teachers becoming self-directed learners.
University learning in the digital age: Investigating how students learn online. Learning in higher education has become more complex since much of the founding research 40 years ago, with online technologies increasingly used to engage a diverse university student population in student-centred learning. The proposed study aims to update our understanding of student learning to this contemporary university context. The project will focus specifically on how students interpret online tasks set by ....University learning in the digital age: Investigating how students learn online. Learning in higher education has become more complex since much of the founding research 40 years ago, with online technologies increasingly used to engage a diverse university student population in student-centred learning. The proposed study aims to update our understanding of student learning to this contemporary university context. The project will focus specifically on how students interpret online tasks set by their teachers, how they complete those tasks by tracking their activities in real-time, and what outcomes they achieve. This study will advance fundamental understanding of these inter-related processes, and provide the stimulus to change thinking about educational design, teaching practices, and support for students.Read moreRead less
School retention and second chance schooling. This project is concerned with ensuring that students who experience systemic disadvantage are not excluded from the benefits of a formal education. It provides an account and critique of the growth of second chance schooling options catering to such students in both Australia and the UK.
Pedagogies for knowledge-building: investigating subject-appropriate, cumulative teaching for twenty-first century school classrooms. To succeed in today's knowledge society, young people need to quickly grasp the organising principles for building different forms of knowledge. This interdisciplinary project explores how teachers marshall the resources of modern classrooms to apprentice students into subject-specific principles for knowledge-building in Science and History.
Innovative measurement approaches to optimise the comparability of large-scale and high-stakes performance assessments. Over 1.2 million Australian school children participate in national and high-stakes state assessments each year. This project aims to produce improved and novel methods for assessing students using open-ended tasks so that educators can more accurately compare students’ achievements and track their progress. In turn, this aims to support decision makers to enable better educati ....Innovative measurement approaches to optimise the comparability of large-scale and high-stakes performance assessments. Over 1.2 million Australian school children participate in national and high-stakes state assessments each year. This project aims to produce improved and novel methods for assessing students using open-ended tasks so that educators can more accurately compare students’ achievements and track their progress. In turn, this aims to support decision makers to enable better educational outcomes. The investigators aim to refine a rubric used in the National Assessment Program—Literacy and Numeracy (NAPLAN) so that Writing assessments are as accurate and comparable as possible. Methods also aim to be designed to enable more accurate and comparable assessments of Australian children in areas not covered by NAPLAN such as History and The Arts.Read moreRead less