Hedgehog Signalling In Limb And Craniofacial Development And Disease
Funder
National Health and Medical Research Council
Funding Amount
$494,544.00
Summary
Anomalies of the face and limbs are amongst the most common features of human birth defects, and their frequent association suggests that the same genes are involved in governing the development of the limbs and face during embryogenesis. We have used a genomics-based approach to identify genes involved in limb development based on their alteration in a mouse model which develops extra fingers and toes. Defects in this mouse result from changes in Gli3, a gene which is known to be important in b ....Anomalies of the face and limbs are amongst the most common features of human birth defects, and their frequent association suggests that the same genes are involved in governing the development of the limbs and face during embryogenesis. We have used a genomics-based approach to identify genes involved in limb development based on their alteration in a mouse model which develops extra fingers and toes. Defects in this mouse result from changes in Gli3, a gene which is known to be important in both limb and face development. Based on the organs in which our genes of interest are active, we believe that they will also play key roles in embryonic development of the limbs, face and other organs. We now plan to investigate the regulation of a subset of these genes based on analysis in mouse models of limb and face development. In addition, we have chosen to further analyse the function of a completely novel gene we have identified which our preliminary studies suggest may play a role in the normal development of the lip and palate. These studies have the potential to shed light on the processes governing how organs develop, as well as on the molecular basis of common birth defects such as polydactyly (extra fingers and toes) and cleft palate.Read moreRead less
Functional Nano-cement Scaffolds For The Treatment Of Osteoporotic Bone Defects
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
Osteoporosis affects 1.2 million Australians and will cost $33.6 billion by 2022. This study aims to develop a novel nano-cement platform for custom-designed bone repair in osteoporosis, by using purpose-designed nanomaterials and advanced 3D printing technique. The research findings will lead to the development of a new bone repair strategy, expand knowledge on both biomaterials engineering and osteoporosis treatment, and improve the quality of life of Australians.
Investigating the effectiveness of teacher education for early career teachers in diverse settings: a longitudinal study. This project investigates the effectiveness of teacher education programs in Victoria and Queensland in preparing teachers for the variety of school settings in which they begin their careers. The findings will inform state and national policy, as well as the work of professional regulation authorities and teacher education providers.
Learning for Teaching in Disadvantaged Schools. This project focuses on what and how primary school teachers learn about improving classroom practices from co-inquiry interventions. The effective diagnosis of student learning difficulties and the design of educational interventions based on such diagnosis is a core component of quality teaching. Yet many teachers have not acquired the knowledge and skills to undertake such learning diagnostic and design work. The project plans to engage practiti ....Learning for Teaching in Disadvantaged Schools. This project focuses on what and how primary school teachers learn about improving classroom practices from co-inquiry interventions. The effective diagnosis of student learning difficulties and the design of educational interventions based on such diagnosis is a core component of quality teaching. Yet many teachers have not acquired the knowledge and skills to undertake such learning diagnostic and design work. The project plans to engage practitioners in co-inquiry through collaborative analysis of professional learning conversations and classroom practices across disadvantaged public schools in urban and regional locations across Queensland. It aims to examine the sustainability of co-inquiry models to improve student learning.Read moreRead less
Quality teaching work and reducing educational inequalities. This project aims to investigate school-based teaching policies and practices using innovative design-based research, to collaboratively develop quality teaching that meets complex, contextual student needs in high poverty communities. Teachers' work in primary schools in high poverty areas is increasingly driven by standards and testing demands. High levels of teacher anxiety and fatigue are apparent in such schools. This project will ....Quality teaching work and reducing educational inequalities. This project aims to investigate school-based teaching policies and practices using innovative design-based research, to collaboratively develop quality teaching that meets complex, contextual student needs in high poverty communities. Teachers' work in primary schools in high poverty areas is increasingly driven by standards and testing demands. High levels of teacher anxiety and fatigue are apparent in such schools. This project will study teaching work in six educationally disadvantaged contexts and identify the different pedagogic approaches that produce sustained increases in student learning. The project intends to develop a collaborative knowledge model that will enhance teacher professionalism and student learning attainment, with highly valuable benefits for the Australian community and economy.Read moreRead less
Educating preservice teachers to teach diverse learners. This project aims to investigate links between teacher educators’ reflexive decision making and the preparation of teachers for teaching in socially and culturally diverse Australian classrooms. The project takes a transdisciplinary approach, bridging the fields of epistemic cognition and reflexive decision making, to explore how rigorous teaching can be enacted in socially and culturally diverse classrooms. Expected outcomes include enh ....Educating preservice teachers to teach diverse learners. This project aims to investigate links between teacher educators’ reflexive decision making and the preparation of teachers for teaching in socially and culturally diverse Australian classrooms. The project takes a transdisciplinary approach, bridging the fields of epistemic cognition and reflexive decision making, to explore how rigorous teaching can be enacted in socially and culturally diverse classrooms. Expected outcomes include enhanced capacity of those preparing future teachers for new classroom conditions, which will provide benefits for a quality teaching workforce.Read moreRead less
Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity th ....Community-based STEM professional learning for teachers of middle years. This project aims to develop a novel community-based program that focuses on a museum-based, teacher professional development program which is based awareness and performance of middle year students in School Science, Technology, Engineering and Mathematics (STEM) education. Improving STEM workforce readiness is critical to producing a more creative society and a leading, dynamic economy. Building STEM education capacity through access to professional learning and museum and STEM professional community resources is critically important for improving students’ proficiencies, attitudes, and interest in STEM. The project outcome will be to develop a STEM professional learning model that can be used to create a more skilled and educated STEM workforce. Read moreRead less
A qualitative and quantitative study of Indigenous content in curriculum. The Indigenous curriculum content in the Australian Curriculum, is tasked as the latest attempt to improve outcomes for Indigenous students. This project aims to investigate how teachers approach this cross-curriculum mandate, consider teachers’ attitudes regarding the teaching of Indigenous content, and identify the complex factors that act as barriers to the success of teaching this content. Employing an innovative desig ....A qualitative and quantitative study of Indigenous content in curriculum. The Indigenous curriculum content in the Australian Curriculum, is tasked as the latest attempt to improve outcomes for Indigenous students. This project aims to investigate how teachers approach this cross-curriculum mandate, consider teachers’ attitudes regarding the teaching of Indigenous content, and identify the complex factors that act as barriers to the success of teaching this content. Employing an innovative design that combines policy analysis, survey research and qualitative research to consider the structural, epistemic and curriculum factors impacting on the success of this policy mandate. This will illuminate the affordances and constraints of new ways of understanding the inclusion of Indigenous content into the curriculum.Read moreRead less
Building on rural knowledges to unlock the potential of rural students. This project aims to advance understanding of the distinctive knowledges that rural students bring to school and develop teaching practices that build on these rural knowledges to unlock the potential of this significant student population. The project involves collaborating with rural primary schools, teachers, students and communities to identify rural knowledges, study classroom practices in detail, and develop sustainabl ....Building on rural knowledges to unlock the potential of rural students. This project aims to advance understanding of the distinctive knowledges that rural students bring to school and develop teaching practices that build on these rural knowledges to unlock the potential of this significant student population. The project involves collaborating with rural primary schools, teachers, students and communities to identify rural knowledges, study classroom practices in detail, and develop sustainable teaching practices that help students connect rural knowledges and school knowledge. Expected outcomes include a framework of place-based teaching practices and resources that will benefit rural schooling, teacher education, and the education of communities crucial to the nation’s future wealth and welfare.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100086
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Teachers' learning in complex times: theorising teacher professional development practices under globalised policy conditions. This project investigates the effects of national standardised testing on the professional development practices of teachers in rural and urban schools in varied Socio-Economic Status communities in Australia. The project will indicate whether and how such testing influences teachers' learning, and subsequent student learning, in these different types of settings.