Refining Methods For Obtaining, Synthesising And Interpreting Research Evidence In Surgery
Funder
National Health and Medical Research Council
Funding Amount
$314,312.00
Summary
Research evidence plays a crucial role in improving clinical care. However the main forms of evidence and the tools that facilitate evidence use - namely randomised controlled trials (RCT) and structured systematic reviews of existing research - have had limited application in surgery for a variety of reasons. This project aims to promote the use of research evidence in surgical decision making by developing tools tailored to the predominance of non-RCTs in surgery and surgeons' information need ....Research evidence plays a crucial role in improving clinical care. However the main forms of evidence and the tools that facilitate evidence use - namely randomised controlled trials (RCT) and structured systematic reviews of existing research - have had limited application in surgery for a variety of reasons. This project aims to promote the use of research evidence in surgical decision making by developing tools tailored to the predominance of non-RCTs in surgery and surgeons' information needs.Read moreRead less
This program of research will develop and evaluate improved strategies for communication and decision making in medical testing for consumers, patients and clinicians. Better understanding about medical tests and improved interventions to support decision making will enable patients and clinicians make more informed and more appropriate decisions about when and when not to test. This work forms part of a broader objective to build health literacy and shared health decision making in Australia.
Strengthening Primary Health Care Systems For Under-served Populations Worldwide
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
The World Health Organization has identified the strengthening of primary health care systems as a priority area for global health. My research program focusses on identifying, developing and testing innovative strategies to improve access to high quality primary health care for under-served populations in Australia (particularly for Aboriginal and Torres Strait Islander communities), rural India, China and the USA.
Novel Health Data Systems For Translation And Impact
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Health research seeks to benefit society by improving health. However, there is a gap between the findings of research and healthcare practice. New systems are beginning to change the way research data are used to improve health outcomes. I am an HIV specialist developing and evaluating several new data systems and my vision for the next four years is to use these to improve the translation of health research into practice and policy for the benefit of people with HIV and society at large.
Systems For Control And Tracking Of Infectious Diseases In A Globalised World
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
Infectious disease informatics now at the forefront of translational research due to the recent rapid growth of microbial genomics, significant advances in molecular diagnostics and increasing demands for real-time biosurveillance. This program of multidisciplinary research will redefine existing paradigms, develop novel systems for surveillance of biothreats and offer new insights into transmission dynamics of pathogens with epidemic potential in Australia.
Advanced Technologies For Improved Molecular Diagnostic And Prognostic Of Gastrointestinal Cancers
Funder
National Health and Medical Research Council
Funding Amount
$473,477.00
Summary
The aim of this interdisciplinary research is to develop innovative and clinically relevant technologies for improved molecular diagnostic of gastrointestinal cancers. It integrates technological advances in physics, bioengineering and nanoscience with state-of-the-art molecular technologies towards the delivery of both fundamental and translational outcomes. These technologies will be applied to address important fundamental questions such as the role of circulating tumour cells.
The Function And Modulation Of Dendritic Activity Underlying Neural Circuits And Behavior
Funder
National Health and Medical Research Council
Funding Amount
$450,641.00
Summary
Understanding how brain cells translate sensory input into behaviour is central to explaining how the brain works. My research focuses on the long-standing question of how information from different brain regions is received and processed within individual brain cells. This research is crucial to understanding brain function and can provide a greater understanding of the neuronal processes underlying diseases such as epilepsy, schizophrenia, depression and alcoholism.
My research objectives centre on new technology development for improving diagnostics and therapeutics applied to skin. I have developed and patented novel devices for minimally invasive topical drug delivery and skin sampling. My leadership and tangible research outcomes are now enabling previously impossible skin research to be done and now are also impacting the commercial sector in addition to creating new knowledge in the field.
Toward An Evidence-based Approach For Treating End-stage Knee Arthritis
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
World-wide more than one million total knee replacements (TKR) will be performed for end-stage knee osteoarthritis in 2016 alone. With an ageing population, demand for this procedure will increase dramatically, placing burden on a constrained health system. Up to 25% of TKR recipients experience on going pain after surgery and are dissatisfied with TKR. My research seeks to improve efficiencies and equitability of this important surgical procedure and in doing so optimise patient outcomes