Deaths In Young People Involved In The Youth Justice System: Towards Evidence-based Prevention
Funder
National Health and Medical Research Council
Funding Amount
$620,705.00
Summary
Young offenders have complex health needs and are at dramatically increased risk of preventable death due to drug overdose, suicide and injury. In order to inform effective prevention, a more detailed understanding of mortality in these young people is required. This project will examine all deaths in young offenders in Queensland from 1993 to 2015, identify targets for prevention, and recommend policy reforms and interventions that are supported by evidence and are culturally appropriate.
Evidence-based Recommendations For Interpregnancy Intervals In High-income Countries
Funder
National Health and Medical Research Council
Funding Amount
$423,305.00
Summary
This study will identify the optimal and harmful interpregnancy intervals for a range of maternal and child outcomes in three high-income countries. With a study population of more than 7.5 million births and a longitudinal study design that matches pregnancies to the same women, this study will inform new interpregnancy interval recommendations for high-income countries that will lead to a reduction in avoidable excess morbidities attributable to uninformed pregnancy planning.
Combating Escalating Harms Associated With Pharmaceutical Opioid Use
Funder
National Health and Medical Research Council
Funding Amount
$925,767.00
Summary
Increases in opioid use have been accompanied by increased opioid harms. But there is a lack of population-level evidence about drivers of long-term prescribed opioid use, dependence, overdose and other harms. Using linked data, we will fill these gaps using a cohort of all people in NSW prescribed opioids since 2002, linked to datasets containing information on health, social and health service utilisation, that will permit a comprehensive assessment of the risks of all prescribed opioids.
Temporal Trends In The Incidence, Site And Survival Of Metastatic Breast Cancer In Australia
Funder
National Health and Medical Research Council
Funding Amount
$190,494.00
Summary
There have been major advances in breast cancer treatment over the last decade. This project will use information collected from the NSW cancer registry and hospitals to report on changes in the type and risk of breast cancer spread and survival for women with a new diagnosis of breast cancer before and after new treatments introduced since 2005. This information is essential for doctors to provide women with up-to-date information; and for planning appropriate health services and research.
Recent Changes In IVF Clinical Practice: Data Linkage To Investigate Their Impact On Fetal Growth And Birth Defects.
Funder
National Health and Medical Research Council
Funding Amount
$219,076.00
Summary
In Australia 1 in 25 births are conceived from IVF treatment and this is increasing with the continuing trend towards later childbearing. This study will use linked population data to assess fetal growth and birth defects in IVF-conceived children following major changes to IVF practice in the last decade. There are limited data internationally on health outcomes following the use of more recent IVF techniques and insufficient data to allow for adequate pre-treatment counselling.
Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.
Seeding Success: Identifying Factors That Contribute To Positive Early Childhood Health And Development In Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$692,845.00
Summary
This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal child ....This study will identify the key drivers of positive early childhood health and development in Aboriginal children, and the features of local communities and early childhood service provision that make a tangible difference, using a large population-based cohort of children in NSW. We will apply novel methods for using linked population data that can be used to inform program planning and evaluation nationally, and will advance theory, research and practice to "seed success" for Aboriginal children.Read moreRead less
Preventing Early Internalising Problems In The Preschool Setting: Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$893,870.00
Summary
Internalising mental health problems reflect inner emotional distress and encompass all symptoms of anxiety and depression. Affecting 1 in 7 Australian school-age children, many internalising problems persist into adulthood, impacting on personal wellbeing, family relations and workforce capabilities. This randomised prevention trial in the preschool-setting, screens for children at-risk and tests if a parenting program can reduce internalising problems across the population by school-entry.
The Efficacy Of N-acetyl Cysteine As An Adjunctive Treatment For First Episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$2,143,069.00
Summary
First episode psychosis may foreshadow devastating, chronic illness. Psychosis follows a staged, progressive pathway. There is evidence to suggest illness progression can be diminished and perhaps even averted if appropriate treatments are given at the early stages of illness. This project will test if N-acetycysteine (NAC) administered to young people who have experienced a first episode of psychosis can help prevent this early psychotic experience from developing into a chronic disorder.
Understanding The Origins Of Diabetes And Kidney Disease In Aboriginal Children And Their Mothers
Funder
National Health and Medical Research Council
Funding Amount
$1,784,613.00
Summary
Aboriginal people experience increased rates of diabetes and kidney disease than non-Aboriginal Australians. This project seeks to understand the role played by the intrauterine events, maternal nutrition, breastfeeding and early growth in the development of diabetes and kidney failure in both Aboriginal mothers and their children.