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Novel Pathways Toward Improving Relapse Prediction In Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Relapse is a devastating problem in schizophrenia and our ability to predict when it occurs is still relatively poor. This project seeks to investigate a new method of tracking relapse by measuring speech and symptom changes across time. This novel design is supported by advanced data modelling methods to provide sensitive predictive ability. This project has the potential to significantly improve relapse prediction in schizophrenia and so support and increase beneficial outcomes for patients
Therapeutic Treatment Pathways And Their Impact On Medicine Safety And Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$336,070.00
Summary
In clinical trials medicines are assumed to be used regularly with a set dose over the duration of the study. However, in real life medicines are used in different doses, over different durations and together with other medicines, which affect the effectiveness and safety of the treatment. The aim of this proposed research is to evaluate how different treatment pathways impact medicine safety and effectiveness. This project will provide new information on safety and effectiveness of treatment pa ....In clinical trials medicines are assumed to be used regularly with a set dose over the duration of the study. However, in real life medicines are used in different doses, over different durations and together with other medicines, which affect the effectiveness and safety of the treatment. The aim of this proposed research is to evaluate how different treatment pathways impact medicine safety and effectiveness. This project will provide new information on safety and effectiveness of treatment pathways.Read moreRead less
Determining The Impact Of Pharmaceutical Opioid Use In Australia: A Focus On Burden, Risks And Harms
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
Despite a dramatic increase in opioid use in Australia and increasing concern about this issue, there are few detailed and robust data on the magnitude of opioid use in the community, and the characteristics of those at risk of adverse outcomes. This program of work will produce unique population-level evidence about the burden, risks and health consequences of opioid use in Australia, to better inform future policies and interventions regarding opioid prescribing to improve clinical outcomes.
Quantifying The Predictors And Risks Of Problematic Alcohol Use
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
This Fellowship will identify the health outcomes, pathways to disability and death, and risk and protective factors for these harms among people with alcohol problems. Projects will include a longitudinal study of people with existing alcohol problems, a longitudinal study of adolescent emerging alcohol consumers, and a field study of alcohol problems in night-time entertainment areas. Findings will inform standardised alcohol screening and intervention and expansion of alcohol treatment.
Using Big Data To Reduce Inappropriate Medication Use
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Potentially inappropriate medication use both increases patient harm and wastes considerable health resources. However methods for measuring patterns of use are not well developed nor utilised in policy. This research will measure the scope, variation and burden of potentially inappropriate medication use in Australia. My unique combination of biostatistical, data and policy expertise will enable this research to create new actionable tools for evaluating the Australian healthcare system.
Population-based Data Linkage To Investigate The Health And Development Of Children Born After IVF
Funder
National Health and Medical Research Council
Funding Amount
$321,972.00
Summary
In Australia 1 in 25 births are conceived from IVF treatment and this is increasing. My research program will use a comprehensive set of linked population data to address key questions in the IVF field following major changes to IVF practice in the last decade. This research (examining fetal growth, birth defects, intellectual disability and school achievement) has the potential to influence clinical practice and will greatly improve the information available for pre-treatment counselling.
Clinical Outcomes From High Risk Medicines In Older Australians
Funder
National Health and Medical Research Council
Funding Amount
$307,946.00
Summary
Older adults frequently take multiple medicines for multiple medical conditions. At present, there is very limited information on the trends and risks associated with medicines use in older Australians. This project will utilise large linked health datasets to determine the prevalence, risk factors and clinical consequences from high risk medicines in older adults in Australia. The findings of this project will contribute to identifying targets to improve prescribing, and health in this populati ....Older adults frequently take multiple medicines for multiple medical conditions. At present, there is very limited information on the trends and risks associated with medicines use in older Australians. This project will utilise large linked health datasets to determine the prevalence, risk factors and clinical consequences from high risk medicines in older adults in Australia. The findings of this project will contribute to identifying targets to improve prescribing, and health in this population.Read moreRead less
Using Total Population Data To Describe The Characteristics Of Respiratory Infections In Order To Predict Future Epidemics And Recommend Vaccination Strategies For Western Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$294,892.00
Summary
Respiratory infections are a major reason for children to go to hospital. I am an epidemiologist and I will be using previously collected and linked laboratory and hospital data from Western Australian children to better understand how these infections flow through the population over different seasons. I will then be able to predict future epidemics of respiratory infections and how different vaccine programs might have an impact in reducing how many children are affected by these infections.