An integrated genomics approach to improve our understanding of the biology of genital campylobacteriosis in beef cattle. Beef is Australia's most valuable agricultural export estimated at $9.6B annually and this industry accounts for one-third of full time employment in regional communities. Currently, unknown causes of reproductive losses in cattle in Northern Australian cost producers approximately $15M per annum. Bovine genital campylobacteriosis is one of the major risk factors associated w ....An integrated genomics approach to improve our understanding of the biology of genital campylobacteriosis in beef cattle. Beef is Australia's most valuable agricultural export estimated at $9.6B annually and this industry accounts for one-third of full time employment in regional communities. Currently, unknown causes of reproductive losses in cattle in Northern Australian cost producers approximately $15M per annum. Bovine genital campylobacteriosis is one of the major risk factors associated with this high cost due to the inability to accurately diagnose the disease. This research will integrate genomics and bioinformatics with infection and vaccination models to improve our understanding of the biology of the disease to develop appropriate control strategies securing Australia's beef industry.Read moreRead less
Identification of Traits and Function by Genomic Matching. Differences between individuals are largely inherited and therefore encoded within the DNA. The challenge is to develop practical means of detecting these differences irrespective of whether they are observable as a phenotype.
Here we focus on livestock. For example, most Australian cattle are horned rather than polled. The inheritance is relatively simple but there is still no DNA test to detect the recessive horning gene.
T ....Identification of Traits and Function by Genomic Matching. Differences between individuals are largely inherited and therefore encoded within the DNA. The challenge is to develop practical means of detecting these differences irrespective of whether they are observable as a phenotype.
Here we focus on livestock. For example, most Australian cattle are horned rather than polled. The inheritance is relatively simple but there is still no DNA test to detect the recessive horning gene.
The genomic matching technique is an in-house patented procedure for identifying such DNA differences. If successful, our test will assist industry to eliminate horning and thereby painful dehorning whilst reducing damage to workers and product.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239218
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Proteomics facility for biotechnology research in WA. The aim of this application is to establish a fully functional proteomics facility to underpin the future research of many groups in four WA institutions. While molecular biological research has thus far concentrated on molecular genetics, it is now vital to directly examine the patterns of proteins expressed by cells to understand their molecular mechanisms. Individual WA researchers have already ventured into proteomics, utilising facilit ....Proteomics facility for biotechnology research in WA. The aim of this application is to establish a fully functional proteomics facility to underpin the future research of many groups in four WA institutions. While molecular biological research has thus far concentrated on molecular genetics, it is now vital to directly examine the patterns of proteins expressed by cells to understand their molecular mechanisms. Individual WA researchers have already ventured into proteomics, utilising facilities located elsewhere in Australia. The reliance on other groups to conduct their proteomics, which are rapidly becoming basic techniques for competitive molecular biological research, is a serious obstacle to biotechnological research in WA.Read moreRead less