Developmental Origins Of Adult Cardiovascular Disease: Vascular Health In The Raine Cohort
Funder
National Health and Medical Research Council
Funding Amount
$1,087,427.00
Summary
The Raine study is a unique long term experiment that has collected extensive pre-birth and childhood data in ~3000 young Australians, who are now 27 years old. We plan to measure the artery health of 1200 of these volunteers and to determine what factors, both before and after birth, influence the presence of early atherosclerosis in humans. This study will guide strategies aimed at early prevention of heart attacks and stroke in humans, by defining the major risk factors.
The identification, prevention and management of chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises a number of research methods to advance our understanding and provide new directions for cardiovascular disease prevention and management.
The Betaproteobacteria: could they play a key role in nitrogen fixation on infertile soils with legumes adapted to climate change? Microbial biosecurity is often overlooked when introducing agricultural species to Australia. As we research new legume species to make our $44 billion agricultural industries robust in the face of a changing climate, we need to be aware of the implications of the associated introduction of (beneficial) microbes. By exploring the globe for plants from regions that al ....The Betaproteobacteria: could they play a key role in nitrogen fixation on infertile soils with legumes adapted to climate change? Microbial biosecurity is often overlooked when introducing agricultural species to Australia. As we research new legume species to make our $44 billion agricultural industries robust in the face of a changing climate, we need to be aware of the implications of the associated introduction of (beneficial) microbes. By exploring the globe for plants from regions that already have the climate we are transitioning towards, we have discovered new perennial forage legumes from which we can build a robust agriculture in the arid regions of southern Australia. This will have enormous national benefit in rural regions. This project will research the essential microbial inoculants associated with these new plants.Read moreRead less