I am a scientist aiming to improve health outcomes by facilitating the collection and unification of data on human genetic variation together with its clinical impact on human health.
Discovery Early Career Researcher Award - Grant ID: DE130100467
Funder
Australian Research Council
Funding Amount
$374,823.00
Summary
Limbs and wings: reconstructing Australian environmental change through innovative analysis of ancient mammal skeletons. An animal's skeleton is the product of a complex relationship between its habits, habitat and evolutionary history. This project uses a vast resource of World Heritage fossil skeletons from Riversleigh to determine how behaviour and ecology of Australia's mammals have changed over the last 25 million years and will need to adapt in the future.
The Eocene high latitude Australasian 'tropics' in a changing climate: resolving conflicting evidence. Between 45 to 30 million years ago, high latitude subtropical floras in Australia and New Zealand experienced significant climate change, leading to the evolution of present day vegetation. Understanding the effects of this climate change on extinction and speciation will produce more accurate predictions about modern floras when faced with climate change.
Testing our knowledge on the dawn of animal life: evidence from the fossil record against modern ecological and morphological analogues. The Cambrian 'Explosion', half a billion years ago, is regarded as one of the most important events in the history of the Earth, when most major animal groups first appear in the rock record, and for which South Australia has recently become a significant source of spectacular fossils. However, important questions remain regarding their Ediacaran roots, the spe ....Testing our knowledge on the dawn of animal life: evidence from the fossil record against modern ecological and morphological analogues. The Cambrian 'Explosion', half a billion years ago, is regarded as one of the most important events in the history of the Earth, when most major animal groups first appear in the rock record, and for which South Australia has recently become a significant source of spectacular fossils. However, important questions remain regarding their Ediacaran roots, the speed of evolution at the time, and the environments in which the radiation took place. Studying the fossil evidence in the light of present-day ecological frameworks, and in comparison with modern behavioural and morphological analogues, as well as living relatives, can help us better assess our understanding of this first radiation of animals.Read moreRead less
Toward a complete view of life on earth via single cell genomics. Genome sequencing has revolutionised biology, but for most microorganisms this revolution has not arrived because the majority cannot be grown in the laboratory. This project will address this grand challenge by targeted sequencing of single cells from the environment that will fill in many major gaps in the microbial tree of life.
Where Gesture Meets Grammar: Crosslinguistic Multimodal Communication. This project aims to investigate both differences and universal tendencies in the interplay of speech and gesture across four languages of importance for Australia. The crucial role of gestures is often overlooked in the analysis of communication. In this project, specialists from linguistics, gesture and cultural studies, psychology and cognitive science collaborate using an innovative approach to generate new knowledge abou ....Where Gesture Meets Grammar: Crosslinguistic Multimodal Communication. This project aims to investigate both differences and universal tendencies in the interplay of speech and gesture across four languages of importance for Australia. The crucial role of gestures is often overlooked in the analysis of communication. In this project, specialists from linguistics, gesture and cultural studies, psychology and cognitive science collaborate using an innovative approach to generate new knowledge about how speech and gesture interact to communicate meaning. The project can provide significant benefits for our understanding of language and cognition, cross-cultural communication in multilingual Australia, and the documentation of endangered languages.Read moreRead less
The developmental genetics of major evolutionary transitions: a multidisciplinary investigation of limb reduction and loss in lizards. The five-toed limb is an iconic evolutionary innovation of land vertebrates, yet has been lost repeatedly. This project will use anatomical, developmental and genetic approaches to understand how vertebrates lose their legs, whether limbs can be reacquired, and the degeneration of limb genes after they lose their function (analogous to 'vestigial organs').
Soundness-guided security analysis for android applications. This project aims to develop a soundness-guided programme analysis to mitigate security threats caused by reflection and dynamic class loading in Android apps, without compromising precision and scalability. Both dynamic code update techniques are widely used in benign and malware apps, but state-of-the-art malware analysis tools ignore or mishandle them, missing security threats and vulnerabilities. The resulting open-source security ....Soundness-guided security analysis for android applications. This project aims to develop a soundness-guided programme analysis to mitigate security threats caused by reflection and dynamic class loading in Android apps, without compromising precision and scalability. Both dynamic code update techniques are widely used in benign and malware apps, but state-of-the-art malware analysis tools ignore or mishandle them, missing security threats and vulnerabilities. The resulting open-source security analysis tool will allow software industries and enterprises (from national security, finance, banking to healthcare, retail, telecommunications) to test their mobile software effectively for code defects or security threats early at software development time at significantly reduced cost.Read moreRead less
Micro Compilers: An Extensible Compiler Architecture for Increased Flexibility and Safety. Programming languages specialised to a particular application domain can cut software development costs and reduce programming errors. Unfortunately, most application domains cannot sustain the costly development and maintenance of the specialised compilers required to implement specialised languages. We address this problem by introducing a novel customisable compiler architecture that can be adapted to ....Micro Compilers: An Extensible Compiler Architecture for Increased Flexibility and Safety. Programming languages specialised to a particular application domain can cut software development costs and reduce programming errors. Unfortunately, most application domains cannot sustain the costly development and maintenance of the specialised compilers required to implement specialised languages. We address this problem by introducing a novel customisable compiler architecture that can be adapted to specialised languages and other special-purpose compiler requirements. Customisable compilers are especially important to a country like Australia that has only limited resources for special purpose developments. Moreover, we will train students at undergraduate and postgraduate level in the area of programming languages and compilers.Read moreRead less