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Australian State/Territory : QLD
Research Topic : DNA microarray
Australian State/Territory : NSW
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Gene Expression (incl. Microarray and other genome-wide approaches) (5)
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  • Funded Activity

    Deciphering The Role Of Atypical DNA Methylation In Neuronal Genome Regulation And Neurological Disorders

    Funder
    National Health and Medical Research Council
    Funding Amount
    $773,484.00
    Summary
    This research will use a combination of genomic, biochemical and functional genomics approaches to investigate the role of the atypical mCH form of DNA methylation in neuronal genome regulation and function, and provide new insights into the role of the epigenome in healthy brain function and neural pathologies.
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    Funded Activity

    Discovery Projects - Grant ID: DP180101405

    Funder
    Australian Research Council
    Funding Amount
    $615,502.00
    Summary
    Genetic variation of single cell transcriptional heterogeneity in HiPSCs. This project aims to investigate whether induced pluripotent stem cells (iPSC) can be used to study the functions of genetic variants associated with human phenotypes and cell fate decisions. The project will utilise technology to produce single cell RNA sequence data for 100,000s of cells. By sequencing individual cells, the genetic control of cellular heterogeneity both within and between cells can be identified, and in .... Genetic variation of single cell transcriptional heterogeneity in HiPSCs. This project aims to investigate whether induced pluripotent stem cells (iPSC) can be used to study the functions of genetic variants associated with human phenotypes and cell fate decisions. The project will utilise technology to produce single cell RNA sequence data for 100,000s of cells. By sequencing individual cells, the genetic control of cellular heterogeneity both within and between cells can be identified, and in doing so, will provide significant benefit by revealing the potential for iPSC to be used for functional translation of human genomics.
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    Funded Activity

    Linkage Projects - Grant ID: LP130100086

    Funder
    Australian Research Council
    Funding Amount
    $467,600.00
    Summary
    Translating genomic discoveries into improved commercial outcomes for the South Sea pearl industry. The purpose of this project is to understand the relationship between gene expression and pearl quality. By identifying the relationship between genes and pearls this project will determine the best conditions to grow selected pearl oyster stocks for the Australian South Sea pearl industry.
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    Funded Activity

    Discovery Projects - Grant ID: DP160100271

    Funder
    Australian Research Council
    Funding Amount
    $398,800.00
    Summary
    Photosynthetic traits as “key performance indicators” of coral health. The objective of this project is to advance knowledge on the healthy functioning of the coral–algal symbiosis, which defines the response of coral reef ecosystems to worldwide environmental change. Current approaches to address this problem have linked coral health to algal symbiont diversity but have been unable to resolve the fundamental symbiont functional traits that govern this link – the “key performance indicators (KPI .... Photosynthetic traits as “key performance indicators” of coral health. The objective of this project is to advance knowledge on the healthy functioning of the coral–algal symbiosis, which defines the response of coral reef ecosystems to worldwide environmental change. Current approaches to address this problem have linked coral health to algal symbiont diversity but have been unable to resolve the fundamental symbiont functional traits that govern this link – the “key performance indicators (KPIs)”. This project plans to couple advanced physiological and functional genomics techniques to transform our understanding of how algal symbiont metabolic KPIs regulate coral growth and stress susceptibility. This may provide new diagnostic capability for the assessment of coral health and may enable us to improve coral reef ecosystem management.
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    Funded Activity

    ARC Future Fellowships - Grant ID: FT110100254

    Funder
    Australian Research Council
    Funding Amount
    $816,756.00
    Summary
    RNA-based analysis for prediction of islet death in diabetes. Death of insulin-producing cells is a common feature in diabetes. Presently, a blood glucose test remains the only blunt instrument to diagnose diabetes. The RNA-based analysis for prediction of islet death in diabetes (RAPID) study links with eight clinical trials to test this newly developed non-invasive assay for predicting diabetes. Early diagnosis will help to reduce diabetic complications in later life.
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    Funded Activity

    Discovery Projects - Grant ID: DP120100729

    Funder
    Australian Research Council
    Funding Amount
    $500,000.00
    Summary
    The role of RNA editing by the brain-specific enzym ADAR3 in learning and memory. Higher-order cognition sets us apart from other species but how this is achieved is still under debate. The project will test the idea, strongly supported by recent genomic analyses, that subtle changes in the sequences of RNA in response to environmental stimuli underpin this extraordinary ability.
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    Showing 1-6 of 6 Funded Activites

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