The Western Australia New Music Archive: 1970 - today: finding, accessing, remembering, performing. This project sees the creation of the Western Australian New Music Archive, a digital repository of and interface to Western Australian music composed from 1970 to the present day. A partnership between peak state and national bodies, the project will also involve the performance and recording of works from the archive.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100123
Funder
Australian Research Council
Funding Amount
$1,100,000.00
Summary
The Digitisation Centre of Western Australia (Phase 1). All five Western Australian Universities, the WA State Library and the WA Museum will collaborate to establish a world-class archival quality Digitisation Centre. There is no existing facility of this kind in WA. During this 12 month project all digitisation equipment will be acquired, installed and used to digitise a diverse range of cultural objects so as to ensure its ability to address the full spectrum of research needs. The Digitisati ....The Digitisation Centre of Western Australia (Phase 1). All five Western Australian Universities, the WA State Library and the WA Museum will collaborate to establish a world-class archival quality Digitisation Centre. There is no existing facility of this kind in WA. During this 12 month project all digitisation equipment will be acquired, installed and used to digitise a diverse range of cultural objects so as to ensure its ability to address the full spectrum of research needs. The Digitisation Centre will form a major piece of national research infrastructure with a prominent international profile and significance. The Centre will have the capacity to digitise all significant Humanities, Arts and Social Sciences (HASS) research collections held by participating institutions within a decade.Read moreRead less
Liquid Biopsy For Personalised Monitoring Of Melanoma Patients
Funder
National Health and Medical Research Council
Funding Amount
$820,888.00
Summary
Despite the success of recent melanoma treatments, therapies are effective long term in only a proportion of patients. Here we will progress preliminary findings in collaboration with biotechnology and pathology companies to develop highly effective companion biomarkers that will aid treatment decisions throughout disease course. Our team will spearhead translation of these markers into the clinic for routine monitoring of melanoma patients.
Deciphering The Role Of Atypical DNA Methylation In Neuronal Genome Regulation And Neurological Disorders
Funder
National Health and Medical Research Council
Funding Amount
$773,484.00
Summary
This research will use a combination of genomic, biochemical and functional genomics approaches to investigate the role of the atypical mCH form of DNA methylation in neuronal genome regulation and function, and provide new insights into the role of the epigenome in healthy brain function and neural pathologies.
Leveraging Genomics Strategies To Generate Adult Neurons From IPSCs And Somatic Cells
Funder
National Health and Medical Research Council
Funding Amount
$1,593,336.00
Summary
Recent advances have made it possible to derive myriad specialized human cells from stem cells or by directly reprogramming cell identity. However, these derived cells are generally arrested at a fetal developmental stage, and do not mature to function like adult cells. We will use new genomic, epigenetic, cell reprogramming, and manipulation methods to discover how to derive mature cells, aiming to generate mature neurons for use in neurobiology research, disease modeling, and drug screening.
EPIGENETIC REPROGRAMMING OF MALIGNANT BREAST CANCER
Funder
National Health and Medical Research Council
Funding Amount
$863,268.00
Summary
Poorly differentiated breast cancers are aggressive tumors, frequently resistant to chemotherapy and associated with high morbidity. Herein we propose the engineering of more selective therapeutic agents able to target the genes involved in cancer initiation and resistance to treatment. We aim to correct and reprogram the cancer cell genome in state that is similar to normal, not tumorigenic cells. This work will generate novel forms of treatment for cancers that are presently not curable.