Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for ....Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for Cryptosporidium, norovirus and adenovirus. Significant benefits include improved diagnostics and water disinfection assays, improved water treatment and reduced costs with global impact.Read moreRead less
Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si a ....Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si alleviates stress in wheat, from gene to farm scale, providing cost-benefit analysis and a best–practice toolbox for implementation by farmers. Outcomes are anticipated to provide a cheaper and more environmentally sustainable solution to issues of water scarcity and yield losses to pests in Australia’s leading crop.Read moreRead less
Development of genetic technology for rodent population suppression. Vertebrate pests cost Australia over $1 billion each year in agricultural losses and environmental damage and novel strategies are urgently required to tackle this massive challenge. Newly proposed “gene drives”, which might rapidly spread through populations, have enormous potential for the sustained management and even eradication of pests. Through innovative application of cutting-edge genome editing approaches, this proposa ....Development of genetic technology for rodent population suppression. Vertebrate pests cost Australia over $1 billion each year in agricultural losses and environmental damage and novel strategies are urgently required to tackle this massive challenge. Newly proposed “gene drives”, which might rapidly spread through populations, have enormous potential for the sustained management and even eradication of pests. Through innovative application of cutting-edge genome editing approaches, this proposal aims to develop gene drive technology in mice as a prototypical vertebrate pest species. We will also develop cutting-edge mathematical models of rodent gene drives to identify crucial parameters for efficacious employment and investigate potential for impact on non-target populations.Read moreRead less
Improving the anti-predator responses of native mammals . Predation by introduced cats and foxes causes extinction and decline in Australian mammals. Protecting threatened mammals inside fenced sanctuaries is effective but they can become overpopulated, inbred and more naive to predators over time. This leads to a dwindling hope of ever restoring them to their natural habitat. Previous research has shown that exposing threatened mammals to low levels of cat predation in large fenced paddocks i ....Improving the anti-predator responses of native mammals . Predation by introduced cats and foxes causes extinction and decline in Australian mammals. Protecting threatened mammals inside fenced sanctuaries is effective but they can become overpopulated, inbred and more naive to predators over time. This leads to a dwindling hope of ever restoring them to their natural habitat. Previous research has shown that exposing threatened mammals to low levels of cat predation in large fenced paddocks improves their anti-predator behaviour, changes their physical appearance and improves survival. This grant seeks to understand the mechanisms (genetic/learning) behind these changes in order to harness and upscale our results and facilitate co-existence between native mammals and introduced predators. Read moreRead less
Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected ....Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected outcomes of the project include practical learnings for application in broader Indigenous community/First Nations capability and supportive policy development contexts. The expected benefits are a long-term platform for enhancing cultural and environmental landscape management and sustainable employment opportunities.Read moreRead less