About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock a ....About time; a new biology for the mineralocorticoid receptor . Temporal control of cell function aligns biological pathways with environmental cues and is critical for optimal heath in mammals. This project will shed light on how a hormone receptor, the MR, modulates time keeping of biological clock time in cells. We will bring together cutting edge genetic modals and bioinformatic approaches with a unique set of research models to define the interaction between the MR and the circadian clock and its role in the normal biology of the heart. New data will significantly enhance our understanding of the biology of MR and cortisol for the circadian time keeping function in peripheral tissues, and gain a clearer understand how our heart cells adapt to environmental circadian disruptors such as shift work. Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100014
Funder
Australian Research Council
Funding Amount
$4,996,503.00
Summary
ARC Research Hub for Supercharging Tropical Aquaculture Through Genetic Solutions. This project will deliver the genetic knowledge to instigate world-leading and highly productive breeding programs for five tropical aquaculture species (barramundi, pearl oyster, prawn, grouper and marine algae) in northern Australia. It will integrate cutting edge genetic and genomic approaches into innovative aquaculture enterprises and will establish a novel understanding of the genetic basis of disease resist ....ARC Research Hub for Supercharging Tropical Aquaculture Through Genetic Solutions. This project will deliver the genetic knowledge to instigate world-leading and highly productive breeding programs for five tropical aquaculture species (barramundi, pearl oyster, prawn, grouper and marine algae) in northern Australia. It will integrate cutting edge genetic and genomic approaches into innovative aquaculture enterprises and will establish a novel understanding of the genetic basis of disease resistance and how the production environment interfaces with the bacterial microbiome, pathogens and water quality to cause disease. Outcomes will lead to increased productivity, international competitiveness, and lowered disease risk and significantly expand Australia's capacity in the aquaculture sector.Read moreRead less
Defining the links between climate change, marine disease and food security. This project will deliver critical new knowledge on the causes of marine pathogen outbreaks that threaten Australia’s $1.6 billion aquaculture industry. Several members of the same genus of bacteria have been implicated in recent mass mortality events in aquaculture species, as well as human illness in consumers of seafood, yet the triggers for unprecedented outbreaks of these pathogens are unknown. By coupling a suite ....Defining the links between climate change, marine disease and food security. This project will deliver critical new knowledge on the causes of marine pathogen outbreaks that threaten Australia’s $1.6 billion aquaculture industry. Several members of the same genus of bacteria have been implicated in recent mass mortality events in aquaculture species, as well as human illness in consumers of seafood, yet the triggers for unprecedented outbreaks of these pathogens are unknown. By coupling a suite of sophisticated molecular biological tools and physiological measurements, this research will resolve the role of environmental disturbances including marine heat waves, floods and plastic pollution in stimulating marine pathogen outbreaks, thereby informing efforts to safeguard Australia’s food security and food safety.Read moreRead less
Integrating fire and predator management to conserve threatened species. This project aims to empower land managers to better conserve Australia’s threatened native animals by developing decision-support approaches that facilitate integrated management of threatening processes. The project will use a combination of novel predictive models, field experiments and data syntheses to assist land managers to better conserve Australia’s threatened native fauna. This project will benefit biodiversity co ....Integrating fire and predator management to conserve threatened species. This project aims to empower land managers to better conserve Australia’s threatened native animals by developing decision-support approaches that facilitate integrated management of threatening processes. The project will use a combination of novel predictive models, field experiments and data syntheses to assist land managers to better conserve Australia’s threatened native fauna. This project will benefit biodiversity conservation by enabling more effective allocation of limited conservation resources.Read moreRead less
Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected ....Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected outcomes of the project include practical learnings for application in broader Indigenous community/First Nations capability and supportive policy development contexts. The expected benefits are a long-term platform for enhancing cultural and environmental landscape management and sustainable employment opportunities.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100027
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates tha ....ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates that will innovate novel diagnostic technologies, enable data-driven decision platforms and address barriers to biosecurity adoption. This suite of graduates and technologies will transform the plant biosecurity sector to protect Australia’s $5.7 trillion natural and productive ecosystems.Read moreRead less