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Current Selection
Status : Active
Australian State/Territory : NSW
Research Topic : DISEASES
Field of Research : Pharmaceutical Sciences
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  • Active Funded Activity

    Discovery Projects - Grant ID: DP190102614

    Funder
    Australian Research Council
    Funding Amount
    $465,000.00
    Summary
    Engineering better sprays for leaf coating: from drop impact to retention. This proposal aims to understand the performance of a unique rheological modifier that can enable an order of magnitude increase in coating efficiency for aerosol sprays while not affecting the quality of droplet formation during spraying. The effect occurs via a dispersed network of fibrous particles in water, providing a weak but useful ability to coat surfaces by responsively adjusting its structure. The material is ex .... Engineering better sprays for leaf coating: from drop impact to retention. This proposal aims to understand the performance of a unique rheological modifier that can enable an order of magnitude increase in coating efficiency for aerosol sprays while not affecting the quality of droplet formation during spraying. The effect occurs via a dispersed network of fibrous particles in water, providing a weak but useful ability to coat surfaces by responsively adjusting its structure. The material is expected to enable a broad array of applications, from agricultural treatments to nasal sprays, by exhibiting responsive behaviour at concentrations much lower than conventional modifiers require. The project will study the responsiveness of the system in single droplet, spray, and coating form as well as an active delivery system.
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    Active Funded Activity

    Linkage Projects - Grant ID: LP190100917

    Funder
    Australian Research Council
    Funding Amount
    $752,366.00
    Summary
    The Fluid-Particle Mechanics of a Synthetic Jet-based Dry Powder Inhaler. This project aims to untangle the fundamental principles that govern the fluid mechanics and particulate interactions in a novel concept chip-based micro-zero-net-mass-flux (micro-ZNMF) jet-assisted dry powder inhaler (DPI). Respiratory diseases affect 6.2 million Australians. The treatment of these diseases is hampered by the poor efficiency of current delivery systems, with conventional DPI devices exhibiting sub-optimum .... The Fluid-Particle Mechanics of a Synthetic Jet-based Dry Powder Inhaler. This project aims to untangle the fundamental principles that govern the fluid mechanics and particulate interactions in a novel concept chip-based micro-zero-net-mass-flux (micro-ZNMF) jet-assisted dry powder inhaler (DPI). Respiratory diseases affect 6.2 million Australians. The treatment of these diseases is hampered by the poor efficiency of current delivery systems, with conventional DPI devices exhibiting sub-optimum performance, delivering typically less than 20% of the loaded dose to the target site, the lungs. The new fundamental knowledge resulting from this research will enable the engineering of a high-efficiency groundbreaking DPI, with the potential to be fully adaptive user-specific benefiting millions of Australians.
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    Active Funded Activity

    Linkage Projects - Grant ID: LP200201026

    Funder
    Australian Research Council
    Funding Amount
    $320,214.00
    Summary
    Plant plasters: Efficient spray micro-coatings for plant delivery. This proposal will study and apply recently-discovered methods of strongly attaching beneficial chemicals to plant leaves, stalks, and fruit. The materials have an unusually good ability to stick to crop plants and deliver herbicide or pesticide active ingredients more efficiently than standard additives, without toxicity. Recent findings have shown significant health risks from commercial herbicide additives and their run-off in .... Plant plasters: Efficient spray micro-coatings for plant delivery. This proposal will study and apply recently-discovered methods of strongly attaching beneficial chemicals to plant leaves, stalks, and fruit. The materials have an unusually good ability to stick to crop plants and deliver herbicide or pesticide active ingredients more efficiently than standard additives, without toxicity. Recent findings have shown significant health risks from commercial herbicide additives and their run-off into vulnerable ecosystems like the Great Barrier Reef. This project will explain the unusually effective, but simple, adhesion and delivery performance, incorporate the new additives into commercially-relevant formulations for our industrial partner, and work to deliver the materials at relevant manufacturing scales.
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    Showing 1-3 of 3 Funded Activites

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