Evaluation of the optic nerve head (optic disc) is important in the diagnosis of various eye diseases, including glaucoma. The influence of genetics on the shape of the optic disc is not well understood because shape is difficult to measure. Using a novel method of shape analysis, this study will examine optic disc shape in populations of Australian twins and individuals with optic nerve disease. It will contribute to the genetic understanding of the optic nerve head and related disorders.
Childhood Retinal Characteristics: Optical Coherence Tomography And Clinical Comparisons
Funder
National Health and Medical Research Council
Funding Amount
$64,631.00
Summary
Optical Coherence Tomography (OCT) of the optic disc and retina has been introduced rapidly into clinical practice, yet there is a paucity of data on its normal distribution or its comparisons with clinical appearances as seen in photographic images. Using the extensive database of OCT and optic disc photos of a population sample of 4091 schoolchildren, influences of confounders (eye size and shape, body size, refraction) will be assessed to aid clinicians in their interpretation of OCT results.