The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your
interaction with the ARDC and use of our national research infrastructure and services. The survey will take
approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure
services including Reasearch Link Australia.
We will use the information you provide to improve the national research infrastructure and services we
deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research
Infrastructure Strategy (NCRIS) program.
Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
The Therapeutic Potential Of Neuroepithelial Cells In The Injured Rat Spinal Cord.
Funder
National Health and Medical Research Council
Funding Amount
$69,684.00
Summary
At present, human spinal cord injury is a permanent disease, as damaged cells (neurons) within the spinal cord are unable to regrow. Early in development, some species have the ability to regrow neurons across a damaged area. The cells that support this regrowth are unknown. These supportive cells could be an effective means of stimulating regrowth in the adult spinal cord. Our aim is to investigate the growth potential of rat embryonic spinal cord cells, for adult spinal cord cell regrowth.
Nfi Genes Regulate The Switch Between Neurogenesis And Gliogenesis During Cortical Development
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Cells within the brain fall into two categories; neurons or glia. Importantly, both derive from a common progenitor population, the radial glia, during development. Early in development radial glia produce neurons, while later they generate glia. The genes which control the switch from neuron production to glia production remain poorly defined. I propose to investigate how this switch is controlled in radial glia, focussing on a family of proteins known to regulate gene transcription.
The Role Of BMP4 Signalling In Oligodendrogenesis Following Central Demyelination
Funder
National Health and Medical Research Council
Funding Amount
$360,202.00
Summary
Multiple Sclerosis (MS) is the most common neurodegenerative disease affecting young adults. It is a disease that kills myelin cells, which are necessary support cells for neurons and are critical for their function. This research investigates the role that BMPs play in myelin cell production and repair. Our aim is to identify regenerative therapeutics for MS.
Identifying Genetic Pathways Underlying The Development Of Distinct Neuronal Subtypes Among Midbrain Dopamine Neurons.
Funder
National Health and Medical Research Council
Funding Amount
$462,709.00
Summary
There is an urgent need in the field of Parkinson's disease (PD) research to develop new strategies aimed at halting progression of the disease (neuroprotection) and alleviaing the symptoms (restorative therapy). This project employs a novel and innovative design to identify genes expressed specifically by the cell type most effected in PD and therefore provide new genetic targets for neuroprotective and resorative therapy.
Creating Stem Cell Niches To Repair The Nigrostriatal System
Funder
National Health and Medical Research Council
Funding Amount
$837,033.00
Summary
It has been difficult to treat Parkinson's with stem cells because transplants make to few new cells and form tumors. In other organs, specialized locations called niches regulate the division and maturation of stem cells. By making a niche in the brains of animals with experimental parkinsonism we induced the brain to make new nerve cells and repair the parkinsonism. This is important because it shows how to use cell based therapies to treat neurodegenerative disorders. .
Molecular Definition Of Neural Pathways In The Embryo And Adult Mouse
Funder
National Health and Medical Research Council
Funding Amount
$401,000.00
Summary
It is our objective to gain insight into the role of the Stem Cell leukaemia (SCL) gene in the central nervous system (CNS). SCL is known to play a crucial role in blood cell development and if aberrantly expressed can lead to T-cell leukemia. Although we do know that SCL is expressed in the brain, its role in the CNS has not been addressed so far and it is of great interest to us to study its potential function in neural development. We have designed a series of experiment in mice to elucidate ....It is our objective to gain insight into the role of the Stem Cell leukaemia (SCL) gene in the central nervous system (CNS). SCL is known to play a crucial role in blood cell development and if aberrantly expressed can lead to T-cell leukemia. Although we do know that SCL is expressed in the brain, its role in the CNS has not been addressed so far and it is of great interest to us to study its potential function in neural development. We have designed a series of experiment in mice to elucidate the expression pattern of SCL in the CNS, to identify the phenotype of neural cells that express SCL in different regions of the mouse brain, and to ablate the SCL gene at different time points during life (during embryonic development, just after birth and during adulthood). These experiments will be performed in conditional transgenic mice that have unique and precisely defined genetic alteration and are generated by us specifically for our research on the SCL-gene. This genetic approach is used to define the neuroanatomical and molecular bases of SCL-function in the brain.Read moreRead less