Early diagnosis of melanoma remains extremely challenging. Currently there are no validated blood-based biomarkers for early diagnosis. Therefore, a reliable screening test is an unmet medical need. Autoantibodies are emerging as promising biomarkers for early cancer detection. In a proof of principle experiment we identified five autoantibodies that provide 95% sensitivity / specificity. Now we will confirm and validate our findings and develop a clinical test for melanoma diagnosis.
Discovery Early Career Researcher Award - Grant ID: DE120101331
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Fundamental electromagnetic modelling of light-biological tissue interactions: a platform for future medical microscopy. Methods for modelling the fundamental electromagnetic interaction of light with biological tissue will be developed. This will allow a range of biomedical optical images to be properly interpreted ultimately leading to the holy grail of quick and minimally invasive methods for detecting cancer.