A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic ev ....A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic evaluation, improving the quality of life and wellbeing of older Australians, and will assist in determining the relative cost effectiveness of new and existing services.
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Discovery Early Career Researcher Award - Grant ID: DE160101394
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Early developmental influences on neocortical organisation. This project seeks to identify the influence of preceding developmental stages on the correct formation of the brain. Development is a sequence of transformations where every stage depends on the outcome of previous stages. The project intends to examine how the early sensory periphery, early-born brain circuits, and intrinsic neuronal interactions affect the subsequent organisation of the cerebral cortex – a mammal-specific brain regio ....Early developmental influences on neocortical organisation. This project seeks to identify the influence of preceding developmental stages on the correct formation of the brain. Development is a sequence of transformations where every stage depends on the outcome of previous stages. The project intends to examine how the early sensory periphery, early-born brain circuits, and intrinsic neuronal interactions affect the subsequent organisation of the cerebral cortex – a mammal-specific brain region responsible for perception, motor planning and cognition. It expects to provide novel mechanistic and conceptual insights into the process of normal brain development and more general biological phenomena, such as development and evolution. It may also provide insights into several genetic and non-genetic causes of brain malformations.Read moreRead less
Defining the earliest events in lymphatic vasculature formation from veins. Vascular system development is one of the earliest events that occurs in the embryo. The entire lymphatic vascular system forms from the embryo’s early veins. This project aims to define the earliest molecular and cellular changes essential to form an entire second vessel network from just a few precursor cells in the embryo. The project aims to utilise zebrafish and mouse embryos to greatly expand knowledge in the forma ....Defining the earliest events in lymphatic vasculature formation from veins. Vascular system development is one of the earliest events that occurs in the embryo. The entire lymphatic vascular system forms from the embryo’s early veins. This project aims to define the earliest molecular and cellular changes essential to form an entire second vessel network from just a few precursor cells in the embryo. The project aims to utilise zebrafish and mouse embryos to greatly expand knowledge in the formation of this essential vertebrate tissue. Ultimately, this is expected to provide new knowledge in stem and precursor cell differentiation, the evolution of complex organ systems and tissue formation. Outcomes may impact on future biotechnology in the areas of tissues engineering, stem cell differentiation and regeneration.Read moreRead less
ARACY/ARC/NHMRC Research Network: Future Generation. Research across a range of disciplines is urgently needed to understand the complexity of pathways contributing to the healthy development of children and young people in modern societies like Australia and to develop effective strategies to improve them. Given our economic prosperity and the level of knowledge about human development, it is profoundly disappointing that many child and youth problems are increasing, creating a crisis in servi ....ARACY/ARC/NHMRC Research Network: Future Generation. Research across a range of disciplines is urgently needed to understand the complexity of pathways contributing to the healthy development of children and young people in modern societies like Australia and to develop effective strategies to improve them. Given our economic prosperity and the level of knowledge about human development, it is profoundly disappointing that many child and youth problems are increasing, creating a crisis in services. This application brings together a highly talented network of researchers to work collaboratively and innovatively with policy makers and those providing services, to enable both new knowledge and implementation of what we already know, to enhance children's futures.Read moreRead less
Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in ....Implementing guidelines to prevent chronic disease in the community. The burden of chronic disease in Australia has resulted in prevention of chronic disease being an important priority for the Australian health system. High quality evidence for preventing chronic disease exists; however the practice falls short of the evidence. Finding ways to implement the evidence for preventing chronic disease is an urgent national need. This study aims to apply the evidence for preventing chronic disease in practice. It will generate data and validate a model on how to effectively improve the uptake of guidelines by both practitioners and consumers. This project is of national and community benefit because it will enable the potential of preventing chronic disease to be realised.Read moreRead less
Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health servic ....Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health services for Indigenous adolescents, Key benefits are 1) A locally-responsive adolescent mental health screening instrument; 2) Comprehensive evidence-informed service model in adolescent mental healthcare; 3) Best practice protocol for developing and managing adolescent mental health as a service delivery stream. Read moreRead less