Inflammation as an early form of maternal-fetal signalling in pregnancy. The project aims to understand the role of inflammatory signalling in marsupial pregnancy. This project is expected to explain why inflammation, a processes normally confined to injury and infection, is a part of reproduction in live-bearing mammals. Outcomes of this project include robust measures of the capacity for, impact of, and evolution of, inflammatory signalling in marsupial pregnancy. The project will provide new ....Inflammation as an early form of maternal-fetal signalling in pregnancy. The project aims to understand the role of inflammatory signalling in marsupial pregnancy. This project is expected to explain why inflammation, a processes normally confined to injury and infection, is a part of reproduction in live-bearing mammals. Outcomes of this project include robust measures of the capacity for, impact of, and evolution of, inflammatory signalling in marsupial pregnancy. The project will provide new knowledge about the unique biology of Australia's marsupial fauna.This project will provide significant benefits, including enhanced capacity for reproduction research in Australia, new international collaborations between Melbourne and Yale, and a new explanation for the puzzling role of inflammation in pregnancy.Read moreRead less
Determining principles for successful episode retrieval of repeated events. This project aims to develop the first-ever set of explanatory principles for how people successfully retain and retrieve individual episode memories from repeated experiences (e.g., one occurrence of a routine social encounter or job-related activity). By deepening our understanding of how memory works, this new knowledge is expected to lay the foundation for interview guidance and ongoing research aimed at enhancing th ....Determining principles for successful episode retrieval of repeated events. This project aims to develop the first-ever set of explanatory principles for how people successfully retain and retrieve individual episode memories from repeated experiences (e.g., one occurrence of a routine social encounter or job-related activity). By deepening our understanding of how memory works, this new knowledge is expected to lay the foundation for interview guidance and ongoing research aimed at enhancing the proficiency of investigations into matters that rely on detailed and accurate accounts of specific episodes. This includes workplace or traffic accident investigations, infectious disease contact tracing, as well as prosecution of repeated sexual offences.Read moreRead less
Cultural responsiveness: measuring and evaluating social work practice. This project aims to develop tools for use by social workers that measure and evaluate culturally responsive practices with Aboriginal and Torres Strait Islander peoples. The tools have potential application across numerous sectors in social work practices with clients and families. The project will benefit social workers who can measure, evaluate and improve their culturally responsive practice, and in turn, the health and ....Cultural responsiveness: measuring and evaluating social work practice. This project aims to develop tools for use by social workers that measure and evaluate culturally responsive practices with Aboriginal and Torres Strait Islander peoples. The tools have potential application across numerous sectors in social work practices with clients and families. The project will benefit social workers who can measure, evaluate and improve their culturally responsive practice, and in turn, the health and well-being outcomes for Aboriginal and Torres Strait Islander peoples.Read moreRead less
Equitable funding for health care: integrating social outcomes. This project will develop an innovative method for decision makers to achieve more equitable allocation of scarce health care resources. Health programs and treatments affect not just health (survival & health related quality of life) but also broader aspects of well-being (e.g. dignity, autonomy, safety). Our current methods for evaluating value for money in health do not capture these aspects. The project will provide benefit by a ....Equitable funding for health care: integrating social outcomes. This project will develop an innovative method for decision makers to achieve more equitable allocation of scarce health care resources. Health programs and treatments affect not just health (survival & health related quality of life) but also broader aspects of well-being (e.g. dignity, autonomy, safety). Our current methods for evaluating value for money in health do not capture these aspects. The project will provide benefit by allowing health system decision makers to achieve fairer allocation of resources across diverse health conditions, interventions and patient populations. Expected outcomes include a new tool for assessing interventions and measuring population health incorporating both health and social outcomes. Read moreRead less
Child Dental Benefit Policies and the Health of Australian Children. This project aims to examine the early effects of two recent initiatives by the Australian government to improve children’s dental health by providing funds to cover essential dental services for children from disadvantaged families. It explores the factors affecting eligible children’s access to benefits from these initiatives and identifies the causal impacts of these changed health care financing arrangements on children’s c ....Child Dental Benefit Policies and the Health of Australian Children. This project aims to examine the early effects of two recent initiatives by the Australian government to improve children’s dental health by providing funds to cover essential dental services for children from disadvantaged families. It explores the factors affecting eligible children’s access to benefits from these initiatives and identifies the causal impacts of these changed health care financing arrangements on children’s consumption of dental services, indicators of oral health and general health, and other indicators of cognitive and non-cognitive development. Using advanced econometric techniques and panel datasets, this project is expected to contribute to the development of effective policies for promoting health and wellbeing.Read moreRead less
The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Open(ing up) goals in physical activity: What works, when, and for whom? This project aims to advance knowledge of open goals as a new goal-setting approach to optimise the adoption and maintenance of physical activity among insufficiently active individuals. This project expects to generate substantive insights into the mechanisms that explain why, when, and for whom open goals are particularly beneficial in this population. Expected outcomes include a theory of open goals that will inform phys ....Open(ing up) goals in physical activity: What works, when, and for whom? This project aims to advance knowledge of open goals as a new goal-setting approach to optimise the adoption and maintenance of physical activity among insufficiently active individuals. This project expects to generate substantive insights into the mechanisms that explain why, when, and for whom open goals are particularly beneficial in this population. Expected outcomes include a theory of open goals that will inform physical activity promotion efforts, with the potential for broad population-level dissemination and scale-up. Significant benefits include the ability to set physical activity goals that are enjoyable and intrinsically motivating to pursue, while also avoiding detrimental effects of current practice (eg high failure rates).Read moreRead less
Reducing Cyberbullying: Turning Bystanders into Constructive Defenders. This project aims to develop a theoretically driven internet-based training program to reduce cyberbullying among adolescents. It expects to discover how to turn passive bystanders (onlookers) into active constructive defenders who help to stop cyberbullying and assist those being cyberbullied. Expected outcomes include developing the first theoretical model of bystanders in the cyberbullying context and practical evidenced ....Reducing Cyberbullying: Turning Bystanders into Constructive Defenders. This project aims to develop a theoretically driven internet-based training program to reduce cyberbullying among adolescents. It expects to discover how to turn passive bystanders (onlookers) into active constructive defenders who help to stop cyberbullying and assist those being cyberbullied. Expected outcomes include developing the first theoretical model of bystanders in the cyberbullying context and practical evidenced-based methods to increase constructive bystanding. The provision of an accessible training program for use in schools will produce significant benefits for the well-being of Australian youth by reducing cyberbullying and increasing the civility of Australian youth.
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Gaining control of the future: The cognitive development of foresight. Because humans can anticipate their limitations, they can act in the present to shape their future for the better.
This project aims to chart four key developmental processes by which children gain this control over their future
outcomes. It will use novel experimental paradigms to map children’s growing ability to compensate for their limits
with strategic planning, and to improve their future capacities by acquiring new kno ....Gaining control of the future: The cognitive development of foresight. Because humans can anticipate their limitations, they can act in the present to shape their future for the better.
This project aims to chart four key developmental processes by which children gain this control over their future
outcomes. It will use novel experimental paradigms to map children’s growing ability to compensate for their limits
with strategic planning, and to improve their future capacities by acquiring new knowledge and innovating
technical solutions. The cognitive underpinnings of these critical behaviours are still poorly understood. This
project will therefore provide the essential empirical foundation for fostering the development of wiser, more
skilled, and more innovative young people.Read moreRead less
Assessing the national productivity impacts of chronic ill health. The project aims to address one of the biggest gaps in health and productivity research by designing a novel composite national metric that will rank lost productivity due to chronic illness The project brings together tax/transfer modelling, health modelling and epidemiological modelling specialists to develop a highly innovative microsimulation model: Health&WorkMOD to then quantify the costs of health-related productivity loss ....Assessing the national productivity impacts of chronic ill health. The project aims to address one of the biggest gaps in health and productivity research by designing a novel composite national metric that will rank lost productivity due to chronic illness The project brings together tax/transfer modelling, health modelling and epidemiological modelling specialists to develop a highly innovative microsimulation model: Health&WorkMOD to then quantify the costs of health-related productivity loss. The proposed model, an international first, will be a powerful tool to comprehensively model the cost impacts of illness and simulate policy options related to health and productivity. This will provide answers to critical policy questions for government with potential significant economic benefits.Read moreRead less