Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and ....Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and a better understanding of long-run health and inequality. These should provide economic and social benefits by informing policy aimed at contemporary social and health challenges, enhancing our understanding of Australian history, and developing public resources.Read moreRead less
Ready, steady, go: Infant motor development and cognition. This project aims to examine the changes in and relationships between cognition and motoric abilities during infancy. The project will utilise well-established and innovative measures of memory flexibility and motor development to generate new knowledge about the complex relationship between action, perception, and cognition. The expected outcomes will provide significant benefits such as increased scientific and public knowledge on earl ....Ready, steady, go: Infant motor development and cognition. This project aims to examine the changes in and relationships between cognition and motoric abilities during infancy. The project will utilise well-established and innovative measures of memory flexibility and motor development to generate new knowledge about the complex relationship between action, perception, and cognition. The expected outcomes will provide significant benefits such as increased scientific and public knowledge on early development and an evidence base on the normal stages of infant development, relevant for health policy.Read moreRead less
Intergenerational Transmission of Inequality. There is a growing interest in the ways in which biological and socioeconomic heritage can shape vulnerabilities to disease. Once viewed as primarily a product of recent conditions such as lifestyle choices, it is now evident that health outcomes can also be shaped by intergenerational mechanisms. Analysis of these in current populations is impractical given the considerable time it would take for a prospective study to unfold. The analysis of histor ....Intergenerational Transmission of Inequality. There is a growing interest in the ways in which biological and socioeconomic heritage can shape vulnerabilities to disease. Once viewed as primarily a product of recent conditions such as lifestyle choices, it is now evident that health outcomes can also be shaped by intergenerational mechanisms. Analysis of these in current populations is impractical given the considerable time it would take for a prospective study to unfold. The analysis of historical populations, however, presents an opportunity to circumvent this obstacle. Using data for male and female convicts and their descendants, this project seeks to determine the extent to which disadvantage experienced by one generation impacted on the life expectancy of those that followed.Read moreRead less
Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptuali ....Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptualisation of absences including those triggered by schools or the care context; and an evidence-informed, child-centred framework to enable attendance and, thereby, improved educational outcomes. This should provide significant social and economic benefits both for children in care and for the community. Read moreRead less