Understanding the evolution of the alternation of generations in the land plant life cycle. This project will investigate the genetic basis and evolution of the land plant life cycle, in which both haploid and diploid phases consist of complex multicellular bodies. The project's findings, which will be made using two model laboratory plants, will be applicable to all plants and will help understand important processes such as pollen and seed production.
A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic ev ....A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic evaluation, improving the quality of life and wellbeing of older Australians, and will assist in determining the relative cost effectiveness of new and existing services.
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Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide ....Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide information on the types of treatment that are needed for these children and what support is needed for their families. The outcomes of this study have the potential to promote the best possible start in life and long term mental health of this group of at risk and disadvantaged young Australians.Read moreRead less
Economic Modelling of the Nurses' Labour Market in Australia. Nurses play an important role in the health system and help to ensure individuals lead healthier, happier and more productive lives. Devising cost-effective policies to ensure an adequate supply of motivated and productive nurses is crucial in achieving efficiency and equity in the health care system. The results will be used by government to help set optimal pay and conditions for nurses, and to ensure that these are competitive with ....Economic Modelling of the Nurses' Labour Market in Australia. Nurses play an important role in the health system and help to ensure individuals lead healthier, happier and more productive lives. Devising cost-effective policies to ensure an adequate supply of motivated and productive nurses is crucial in achieving efficiency and equity in the health care system. The results will be used by government to help set optimal pay and conditions for nurses, and to ensure that these are competitive with other nurse employers. This will provide a firm evidence-base to reduce nurse shortages and therefore increase the quality of patient care in Australia.Read moreRead less
The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessmen ....Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessment of the distributional impact of a wide range of possible reforms, including how the outcomes of any policy change will affect disadvantaged sections of our society, whether different generations will be fairly treated, and the impact by gender.Read moreRead less
Measuring Hospital Performance: Outputs, Quality of Care, Competition and Efficiency. Hospitals are a critical component of the health infrastructure. An understanding of the performance of hospitals is important in shaping an overall health care strategy. Unfortunately, assessing hospital performance has been fraught with difficulties. A major obstacle is in defining and measuring the outputs and quality of hospitals. Collaborating with the Victorian Department of Human Services, and using t ....Measuring Hospital Performance: Outputs, Quality of Care, Competition and Efficiency. Hospitals are a critical component of the health infrastructure. An understanding of the performance of hospitals is important in shaping an overall health care strategy. Unfortunately, assessing hospital performance has been fraught with difficulties. A major obstacle is in defining and measuring the outputs and quality of hospitals. Collaborating with the Victorian Department of Human Services, and using the Department's VAED datasets, we aim to develop a framework within which unobservable quality dimensions can be estimated, so that hospital output and quality can be accounted for. The framework will be useful for addressing pertinent health policy issues, including hospital funding, specialisation, and competition issues.Read moreRead less
Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in thei ....Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in their mental health and significant cost savings to the community.Read moreRead less
Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health ....Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health of adults with ID that has been undertaken internationally to date. The population will cover the age span of late adolescence (16 years) through the transition to adult life then through to the elderly. The research will establish the prevalence and nature of mental illness and potential risk factors in a large representative population of adults with ID.Read moreRead less
The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced pol ....The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced policy infrastructure using new methods and interdisciplinary approaches. Significant benefits include improvements to: (1) policy management by government departments; (2) the health and wellbeing of the Australians they serve; (3) our Partners' capacity to consult governments on how technology can assist policy management. Read moreRead less