How Are Periodontal Disease And Rheumatoid Arthritis Inter-related?
Funder
National Health and Medical Research Council
Funding Amount
$563,262.00
Summary
Periodontal (gum) disease and rheumatoid arthritis are two of the most common chronic inflammatory diseases affecting humans. These two diseases have remarkably similar patterns of tissue destruction. It is possible that chronic periodontitis may prime or predispose susceptible individuals to developing rheumatoid arthritis. Treatment of periodontal disease may help reduce the severity of rheumatoid arthritis.
Comparison Of Periodontal Ligament Stem Cells And Induced Pluripotent Periodontal Ligament Stem Cells For Periodontal Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$831,955.00
Summary
In the first part of this study we will determine whether induced pluripotent stem cells or adult stem cells from the periodontal ligament are better candidates for periodontal regeneration. Secondly, using CAD/CAM technology we will make tissue engineering scaffolds tailored to fit periodontal defects and seeded with stem cells to improve on current techniques used to regenerate damaged tissues around teeth affected by periodontal disease.