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Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Rethinking and revitalising herbicides to counter resistance. Weeds and increasingly herbicide resistant weeds are the major yield penalty for agriculture. This project aims to develop innovative ways to overcome resistance. This project expects to (i) make herbicides work more efficiently, (ii) reveal a new mode of action for an under-used herbicide and (iii) assign breakdown pathways to herbicides. Expected outcomes of this project are to (i) to find rare, but truly synergistic herbicide combi ....Rethinking and revitalising herbicides to counter resistance. Weeds and increasingly herbicide resistant weeds are the major yield penalty for agriculture. This project aims to develop innovative ways to overcome resistance. This project expects to (i) make herbicides work more efficiently, (ii) reveal a new mode of action for an under-used herbicide and (iii) assign breakdown pathways to herbicides. Expected outcomes of this project are to (i) to find rare, but truly synergistic herbicide combinations; (ii) reveal a herbicide against which weeds outside of Japan have not evolved resistance to; and (iii) establish how best to make breakdown blockers. A benefit of using existing herbicides is the approaches are close to market, so with partner Nexgen Plants, its outcomes can be commercialised.Read moreRead less
Novel biological and genetic disease control tools for the barley industry. This project places Australian barley breeders at the forefront of disease resistance by providing them with novel tools to develop varieties with enhanced protection against fungal diseases. The aims are to produce fungal strains with multiple virulence genes for fast and cost-effective testing of barley lines, untangle the fungal/host gene interaction for resistance breeding and identify new sources of resistance. The ....Novel biological and genetic disease control tools for the barley industry. This project places Australian barley breeders at the forefront of disease resistance by providing them with novel tools to develop varieties with enhanced protection against fungal diseases. The aims are to produce fungal strains with multiple virulence genes for fast and cost-effective testing of barley lines, untangle the fungal/host gene interaction for resistance breeding and identify new sources of resistance. The outcomes will lead to the commercialisation by Australian breeding companies of barley varieties with durable fungal resistance. This will benefit the Australian economy by providing sustainability and protection for barley breeding thereby significantly reducing crop losses for this important global agricultural commodity.Read moreRead less
Mid-Career Industry Fellowships - Grant ID: IM230100025
Funder
Australian Research Council
Funding Amount
$747,126.00
Summary
Using the blackleg fungus as a model for maximising fungicide efficacy. Resistance to chemicals impacts the ability to control many diseases across many crops. This project aims to identify key epidemiological factors contributing to fungicide resistance in an emerging model system, blackleg disease of canola, using innovative approaches. The outcomes of this research will be management strategies for minimising the risk of evolution of fungicide resistance, a key industry need. This will also e ....Using the blackleg fungus as a model for maximising fungicide efficacy. Resistance to chemicals impacts the ability to control many diseases across many crops. This project aims to identify key epidemiological factors contributing to fungicide resistance in an emerging model system, blackleg disease of canola, using innovative approaches. The outcomes of this research will be management strategies for minimising the risk of evolution of fungicide resistance, a key industry need. This will also enhance interdisciplinary collaborations through combining field and molecular research. These management strategies will provide significant economic benefits by ensuring increased canola yields, whilst providing health and environmental benefits through minimisation of unnecessary use of fungicides.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100282
Funder
Australian Research Council
Funding Amount
$475,181.00
Summary
Delivering breeding-oriented genetic tools for cereal disease resistance. This project will focus specifically on delivering the genetic tools to the industry partner to assist its wheat and barley breeders to increase the accuracy and efficiency of incorporating the durable wheat stripe rust disease and barley leaf rust disease resistance into their core germplasm collections, respectively. The expected outcomes will also contribute to filling our knowledge gap in understanding the cereal rust ....Delivering breeding-oriented genetic tools for cereal disease resistance. This project will focus specifically on delivering the genetic tools to the industry partner to assist its wheat and barley breeders to increase the accuracy and efficiency of incorporating the durable wheat stripe rust disease and barley leaf rust disease resistance into their core germplasm collections, respectively. The expected outcomes will also contribute to filling our knowledge gap in understanding the cereal rust innate immune system and benefit other cereal fungal pathosystems. The wide application of the expected outcomes from the proposed project will reduce the utilisation of fungicides and subsequently will subsequently contribute to the resilience of cereal crops and sustainable global food security.Read moreRead less
Does plasma membrane perception of 2,4-D influence auxin resistance? This project aims to investigate the role of the cell membrane in synthetic auxin herbicide resistance by analysing the functions and interaction partners of candidate resistance proteins. It is expected that this project will generate new knowledge about the very early response of plants to auxin and the difference between susceptible and resistant weeds in perceiving auxin herbicides. Expected outcomes of this project include ....Does plasma membrane perception of 2,4-D influence auxin resistance? This project aims to investigate the role of the cell membrane in synthetic auxin herbicide resistance by analysing the functions and interaction partners of candidate resistance proteins. It is expected that this project will generate new knowledge about the very early response of plants to auxin and the difference between susceptible and resistant weeds in perceiving auxin herbicides. Expected outcomes of this project include the identification of potential herbicide synergists and a greater understanding of how weeds develop resistance to auxin herbicides. This should benefit Australian grain growers by providing more effective weed control options and lessening the amount of unnecessarily-applied herbicide in the environment.Read moreRead less
Investigating a novel genetic strategy for insect resistance in crops. Plants are in a constant battle with insect pests and there is an increasing reliance on chemical inputs for control. However there are incoming bans on some pesticides, and new approaches are required for pest management. The aim of this project is to develop a new strategy which exploits the dependence of herbivorous insects on phytosterols. Here, we will apply the latest genomics technologies in plants to produce non-utili ....Investigating a novel genetic strategy for insect resistance in crops. Plants are in a constant battle with insect pests and there is an increasing reliance on chemical inputs for control. However there are incoming bans on some pesticides, and new approaches are required for pest management. The aim of this project is to develop a new strategy which exploits the dependence of herbivorous insects on phytosterols. Here, we will apply the latest genomics technologies in plants to produce non-utilizable sterols which will not support insect growth and reproduction, but will still allow the plant to function normally. We will demonstrate this in the important crop canola. Translation of this knowledge will support breeding for crop resilience, leading to durable resistance and more sustainable crop production.Read moreRead less
Eco-friendly pesticides for crop protection. The aims of the project are to develop robust methods for measuring bioactive pesticidal molecules in butterfly pea cultivars, characterise their modes of action, determine the exposure and persistence of these molecules in field runoff and waterways and, in the longer term, develop butterfly pea cultivars with optimised bioactivity and safety. The major outcome of the project is the generation of new knowledge that will contribute to the development ....Eco-friendly pesticides for crop protection. The aims of the project are to develop robust methods for measuring bioactive pesticidal molecules in butterfly pea cultivars, characterise their modes of action, determine the exposure and persistence of these molecules in field runoff and waterways and, in the longer term, develop butterfly pea cultivars with optimised bioactivity and safety. The major outcome of the project is the generation of new knowledge that will contribute to the development of novel antifungal and insecticidal agents. This outcome is significant as there is a huge need for new pesticidal agents that exhibit wide safety margins, reduce problems associated with resistance to existing treatments, and that are safe for the environment.Read moreRead less
A peptide platform to fight pests threatening global food security. This project aims to develop a platform technology for the efficient design of new crop protection agents based on peptides to protect Australia’s food security. It will be first applied against the highly destructive fall armyworm, currently spreading alarmingly in Australia. The project is significant because insect pests cause huge economic and environmental impacts. Peptides are a new generation of crop protection agents tha ....A peptide platform to fight pests threatening global food security. This project aims to develop a platform technology for the efficient design of new crop protection agents based on peptides to protect Australia’s food security. It will be first applied against the highly destructive fall armyworm, currently spreading alarmingly in Australia. The project is significant because insect pests cause huge economic and environmental impacts. Peptides are a new generation of crop protection agents that are potentially more effective and sustainable than chemical pesticides. Expected outcomes are a new rapid response technology and associated lead molecules to protect against current and emerging pests. Major benefits are increased food security, improved crop yields and a more sustainable agriculture industry. Read moreRead less
Extracellular vesicles in the pathogenesis of fungal plant disease. Extracellular vesicles (EVs) are small membrane bound sacs that carry information between cells in essentially all organisms. EVs are also produced by bacterial and fungal pathogens and have a crucial role in infection in mammals . We propose that fungal EVs are key players in the establishment of fungal diseases in plants. We have isolated EVs from the cereal pathogen Fusarium graminearum which decreases yield and quality of gr ....Extracellular vesicles in the pathogenesis of fungal plant disease. Extracellular vesicles (EVs) are small membrane bound sacs that carry information between cells in essentially all organisms. EVs are also produced by bacterial and fungal pathogens and have a crucial role in infection in mammals . We propose that fungal EVs are key players in the establishment of fungal diseases in plants. We have isolated EVs from the cereal pathogen Fusarium graminearum which decreases yield and quality of grain in major food crops such as wheat, barley and corn. This project will focus on the cargo that EVs transport through the fungal cell wall and into the plant host and will establish the role of this cargo in disease progression. Ultimately, this knowledge will be used to design new strategies for disease control.Read moreRead less